Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Carlo, Mustazza"'
Autor:
Alessia Panusa, Roberto Cirilli, Francesca Romana Gallo, Carlo Mustazza, Giuseppina Multari, Giovanna Palazzino
Publikováno v:
Journal of Food Composition and Analysis. 92:103515
Iberin (IBR) is an isothiocyanate (ITC) with chemopreventive properties on different types of cancer. The need of quantifying IBR either in natural products or in food supplements makes the availability of suitable and stable analytical standards nec
Publikováno v:
Annali dell'Istituto superiore di sanita. 54(4)
Publikováno v:
Current medicinal chemistry. 27(33)
Prion pathologies are fatal neurodegenerative diseases caused by the misfolding of the physiological Prion Protein (PrPC) into a β-structure-rich isoform called PrPSc. To date, there is no available cure for prion diseases and just a few clinical tr
Publikováno v:
Current medicinal chemistry. 25(20)
Nociceptin /Orphanin FQ Peptide” receptor (NOPr) is a G-protein-coupled receptor with the nociceptin/orphanin FQ peptide (N/OFQ) as endogenous agonist. It is expressed in the nervous system as well as in some non-neural tissues. Its activation has
Autor:
Andrea Rodomonte, Carlo Mustazza, Luisa Valvo, Piera Di Martino, Isabella Sestili, Anna Borioni, Maria Cristina Gaudiano, Eliana Costantini, Monica Bartolomei, Eleonora Antoniella
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 96:170-186
Novel synthetic analogs of Sildenafil are constantly detected as adulterants in counterfeit drugs and dietary supplements. Their intake constitutes a serious health hazard as side effects are unknown. In this paper an investigation is carried out on
Publikováno v:
Med. Chem. Commun.. 3:357-361
The research into selective ligands of misfolded protein plaques in Alzheimer's disease and in transmissible spongiform encephalopathies led to compound 3, based on the Congo Red framework and bearing two trifluoromethoxy groups. Histochemical experi
Autor:
Carlo Mustazza, Maria Sbraccia, Maria Rosaria Del Giudice, Anna Borioni, Giuditta Bastanzio, Isabella Sestili
Publikováno v:
European Journal of Medicinal Chemistry. 46:1207-1221
Bivalent ligands constituted by two identical pharmacophores structurally related to the Nociceptin Opioid Receptor (NOPr) antagonist JTC-801 were synthesized and their binding affinities for NOPr were evaluated. The novel ligands are formed by two m
Autor:
Giuditta Bastanzio, Carlo Mustazza
Publikováno v:
Medicinal Research Reviews. 31:605-648
The nociceptin opioid (NOP) receptor is the most recently discovered member of the family of the opioid receptors; its endogenous agonist is the peptide nociceptin. Due to the subsequent elucidation of its physiological role in both central and perip
Autor:
Andrea Rodomonte, Isabella Sestili, Maria Rosaria Del Giudice, Carlo Mustazza, Maria Sbraccia, Anna Borioni
Publikováno v:
Journal of Medicinal Chemistry. 51:1058-1062
Some synthesized 1,2-dihydrospiro[isoquinoline-4(3 H),4'-piperidin]-3-ones were evaluated as ligands for nociceptin receptor (NOP receptor). Their affinity was established by binding studies, and efficacy was investigated by GTP binding experiments.
Autor:
Luca Regazzoni, Giampaolo Incarnato, Carlo Mustazza, Raffaele Lecce, Alessia Panusa, R. Porrà
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 125
Commission regulation (EU) No 358/2014 amending the new regulation (EC) No 1223/2009 on cosmetics has prohibited the use of isopropyl-, isobutyl-, phenyl-, benzyl- and pentylparaben. Furthermore, Commission regulation (EU) No 1004/2014 has lowered th