Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Carlo, Brugnara"'
Autor:
Serge Cedrick Toya Mbiandjeu, Angela Siciliano, Alessandro Mattè, Enrica Federti, Massimiliano Perduca, Davide Melisi, Immacolata Andolfo, Angela Amoresano, Achille Iolascon, Maria Teresa Valenti, Francesco Turrini, Michele Bovi, Arianna Pisani, Antonio Recchiuti, Domenico Mattoscio, Veronica Riccardi, Luca Dalle Carbonare, Carlo Brugnara, Narla Mohandas, Lucia De Franceschi
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 454 (2024)
Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here, we s
Externí odkaz:
https://doaj.org/article/6113bcf2028948f886726cd52fe80fab
Autor:
Alessandro Mattè, Enrica Federti, Antonio Recchiuti, Moayed Hamza, Giulia Ferri, Veronica Riccardi, Jacopo Ceolan, Alice Passarini, Filippo Mazzi, Angela Siciliano, Deepak L Bhatt, David Coughlan, John Climax, Elisa Gremese, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
Inflammatory vasculopathy is critical in sickle cell disease (SCD)-associated organ damage. An imbalance between pro-inflammatory and pro-resolving mechanisms in response to different triggers such as hypoxia/reoxygenation or infections has been prop
Externí odkaz:
https://doaj.org/article/4fbd0b212afd45d98532086bb0bd5574
Autor:
Alessandro Matte, Anand B. Wilson, Federica Gevi, Enrica Federti, Antonio Recchiuti, Giulia Ferri, Anna Maria Brunati, Mario Angelo Pagano, Roberta Russo, Christophe Leboeuf, Anne Janin, Anna Maria Timperio, Achille Iolascon, Elisa Gremese, Lenny Dang, Narla Mohandas, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Hereditary spherocytosis (HS) is the most common, nonimmune, hereditary, chronic hemolytic anemia after hemoglobinopathies. The genetic defects in membrane function causing HS lead to perturbation of the RBC metabolome, with altered glycolysis. In mi
Externí odkaz:
https://doaj.org/article/dca369d1197d4e2db25239462d156007
Autor:
Alessandro Matte’, Richard Pozzetto Huot, Andrea Mattarei, Alberto Ongaro, Alice Passarini, Angela Siciliano, Roberta Russo, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
HemaSphere, Vol 7, p e20723c9 (2023)
Externí odkaz:
https://doaj.org/article/4d77a2aa99d84928ab88063f1d87014a
Autor:
Enrica Federti, Alessandro Matte, Antonio Recchiuti, Francesca Garello, Alessandra Ghigo, Wassim El Nemer, Enzo Terreno, Angela Amoresano, Domenico Mattoscio, Franco Turrini, Christophe Lebouef, Anne Janin, Antonella Pantaleo, Roberta Russo, Mickael Marin, Iana Iatcencko, Veronica Riccardi, Angela Siciliano, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
HemaSphere, Vol 7, Iss 3, p e848 (2023)
Drug repurposing is a valuable strategy for rare diseases. Sickle cell disease (SCD) is a rare hereditary hemolytic anemia accompanied by acute and chronic painful episodes, most often in the context of vaso-occlusive crisis (VOC). Although progress
Externí odkaz:
https://doaj.org/article/c8c05eebb53a44d484b867d2b88dc0d7
Autor:
Alessandro Mattè, Penelope A. Kosinski, Enrica Federti, Lenny Dang, Antonio Recchiuti, Roberta Russo, Angela Siciliano, Veronica Riccardi, Anne Janin, Matteo Mucci, Christophe Leboeuf, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi
Publikováno v:
Haematologica, Vol 108, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/29ab57f703ca467ca865adac1fdc12ac
Autor:
Thomas Pincez, Ken Sin Lo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Melanie E. Garrett, Carlo Brugnara, Allison E. Ashley-Koch, Marilyn J. Telen, Frederic Galacteros, Philippe Joly, Pablo Bartolucci, Guillaume Lettre
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Several of the complications observed in sickle cell disease (SCD) are influenced by variation in hematologic traits (HT), such as fetal hemoglobin (HbF) level and neutrophil count. Previous large-scale genome-wide association studies carried out in
Externí odkaz:
https://doaj.org/article/166842d6076144de914c1868e81d6859
Autor:
Martha A. Clark, Usheer Kanjee, Gabriel W. Rangel, Laura Chery, Anjali Mascarenhas, Edwin Gomes, Pradipsinh K. Rathod, Carlo Brugnara, Marcelo U. Ferreira, Manoj T. Duraisingh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
During Plasmodium intra-erythrocytic developmental, parasites compromise the structural integrity of host red-blood cells. Here, Clark et al. develop a flow cytometric osmotic stability assay to show that P. vivax infection destabilizes host reticulo
Externí odkaz:
https://doaj.org/article/048bfeac5af7438dad7b6d45ad8104b5
Autor:
Boris E. Shmukler, Alicia Rivera, Katherine Nishimura, Ann Hsu, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Carlo Brugnara, Seth L. Alper
Publikováno v:
Physiological Reports, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract Investigation of erythrocytes from spontaneous or engineered germ‐line mutant mice has been instrumental in characterizing the physiological functions of components of the red cell cytoskeleton and membrane. However, the red blood cell exp
Externí odkaz:
https://doaj.org/article/d667a7d9ab254affa515e66dbfbdc6b5
Autor:
David H. Vandorpe, Boris E. Shmukler, Yann Ilboudo, Swati Bhasin, Beena Thomas, Alicia Rivera, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Colin Sieff, Manoj Bhasin, Guillaume Lettre, Carlo Brugnara, Seth L. Alper
Publikováno v:
Haematologica, Vol 106, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/4117e97a78454c9ca4a2e952330e49e9