Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carlisle R. DeJulius"'
Autor:
Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo, Ashley B. Cavnar, Lauren M. Babb, Nora Francini, Eva F. Gbur, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook, Craig L. Duvall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The high potential of siRNAs to silence oncogenic drivers remains largely untapped due to the challenges of tumor cell delivery. Here, divalent lipid-conjugated siRNAs are optimized for in situ binding to albumin to improve pharmacokinetics
Externí odkaz:
https://doaj.org/article/a8ad79f8d57c45aeac75fe1a848bd947
Autor:
Sarah Naguib, Carlisle R. DeJulius, Jon R. Backstrom, Ameer A. Haider, John M. Ang, Andrew M. Boal, David J. Calkins, Craig L. Duvall, Tonia S. Rex
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 556 (2023)
Erythropoietin (EPO) is neuroprotective in multiple models of neurodegenerative diseases, including glaucoma. EPO-R76E retains the neuroprotective effects of EPO but diminishes the effects on hematocrit. Treatment with EPO-R76E in a glaucoma model in
Externí odkaz:
https://doaj.org/article/f425def142764bd78d4e216706b866ad
Autor:
Richard d’Arcy, Farah El Mohtadi, Nora Francini, Carlisle R. DeJulius, Hyunmoon Back, Arianna Gennari, Mike Geven, Maria Lopez-Cavestany, Zulfiye Yesim Turhan, Fang Yu, Jong Bong Lee, Michael R. King, Leonid Kagan, Craig L. Duvall, Nicola Tirelli
Publikováno v:
D'Arcy, R, El Mohtadi, F, Francini, N, Dejulius, C R, Back, H, Gennari, A, Geven, M, Lopez-Cavestany, M, Turhan, Z Y, Yu, F, Lee, J B, King, M R, Kagan, L, Duvall, C L & Tirelli, N 2022, ' A Reactive Oxygen Species-Scavenging Stealth' Polymer, Poly(thioglycidyl glycerol), Outperforms Poly(ethylene glycol) in Protein Conjugates and Nanocarriers and Enhances Protein Stability to Environmental and Biological Stressors ', Journal of the American Chemical Society, vol. 144, no. 46, pp. 21304-21317 . https://doi.org/10.1021/jacs.2c09232
This study addresses well-known shortcomings of poly(ethylene glycol) (PEG)-based conjugates. PEGylation is by far the most common method employed to overcome immunogenicity and suboptimal pharmacokinetics of, for example, therapeutic proteins but ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d084ca9f80077be1bc82ced68025a47
https://doi.org/10.1021/jacs.2c09232
https://doi.org/10.1021/jacs.2c09232
Autor:
Ella N. Hoogenboezem, Shrusti S. Patel, Ashley B. Cavnar, Justin H. Lo, Lauren M. Babb, Nora Francini, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook, Craig L. Duvall
Publikováno v:
bioRxiv
The high potential for therapeutic application of siRNAs to silence traditionally undruggable oncogenic drivers remains largely untapped due to the challenges of tumor cell delivery. Here, siRNAs were optimized forin situbinding to albumin through C1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed437d3b4e1884a99c1762f14a4e284b
https://doi.org/10.1101/2023.02.14.528574
https://doi.org/10.1101/2023.02.14.528574
Autor:
Shrusti S. Patel, Ella N. Hoogenboezem, Fang Yu, Carlisle R. DeJulius, R. Brock Fletcher, Alex G. Sorets, Fiona K. Cherry, Justin H. Lo, Mariah G. Bezold, Nora Francini, Richard d’Arcy, Jordan E. Brasuell, Rebecca S. Cook, Craig L. Duvall
Publikováno v:
Biomaterials. 297:122098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1276b7e1e8ea830351a1a71c1114dbd
https://doi.org/10.1016/j.biomaterials.2023.122098
https://doi.org/10.1016/j.biomaterials.2023.122098
Autor:
Prarthana Patil, Katherine A. Russo, Joshua T. McCune, Alonda C. Pollins, Matthew A. Cottam, Bryan R. Dollinger, Carlisle R. DeJulius, Mukesh K. Gupta, Richard D’Arcy, Juan M. Colazo, Fang Yu, Mariah G. Bezold, John R. Martin, Nancy L. Cardwell, Jeffrey M. Davidson, Callie M. Thompson, Adrian Barbul, Alyssa H. Hasty, Scott A. Guelcher, Craig L. Duvall
Publikováno v:
Sci Transl Med
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic biomaterials are less expensive to manufacture than biologic dressings and can achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986208244b0eeacb3190538537161e03
https://doi.org/10.1126/scitranslmed.abm6586
https://doi.org/10.1126/scitranslmed.abm6586