Zobrazeno 1 - 10
of 568
pro vyhledávání: '"Carlisle R"'
Autor:
Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo, Ashley B. Cavnar, Lauren M. Babb, Nora Francini, Eva F. Gbur, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook, Craig L. Duvall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The high potential of siRNAs to silence oncogenic drivers remains largely untapped due to the challenges of tumor cell delivery. Here, divalent lipid-conjugated siRNAs are optimized for in situ binding to albumin to improve pharmacokinetics
Externí odkaz:
https://doaj.org/article/a8ad79f8d57c45aeac75fe1a848bd947
Autor:
Sarah Naguib, Carlisle R. DeJulius, Jon R. Backstrom, Ameer A. Haider, John M. Ang, Andrew M. Boal, David J. Calkins, Craig L. Duvall, Tonia S. Rex
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 556 (2023)
Erythropoietin (EPO) is neuroprotective in multiple models of neurodegenerative diseases, including glaucoma. EPO-R76E retains the neuroprotective effects of EPO but diminishes the effects on hematocrit. Treatment with EPO-R76E in a glaucoma model in
Externí odkaz:
https://doaj.org/article/f425def142764bd78d4e216706b866ad
Autor:
Myers R, Grundy M, Rowe C, Coviello CM, Bau L, Erbs P, Foloppe J, Balloul JM, Story C, Coussios CC, Carlisle R
Publikováno v:
International Journal of Nanomedicine, Vol Volume 13, Pp 337-349 (2018)
Rachel Myers,1 Megan Grundy,2 Cliff Rowe,1 Christian M Coviello,1 Luca Bau,2 Philippe Erbs,3 Johann Foloppe,3 Jean-Marc Balloul,3 Colin Story,1 Constantin C Coussios,2 Robert Carlisle2 1OxSonics Ltd, The Magdalen Centre, 2BUBBL, IBME, Department of E
Externí odkaz:
https://doaj.org/article/c577637403ca43e89c1b3be55c5fe0f8
Autor:
Patel, Shrusti S., Hoogenboezem, Ella N., Yu, Fang, DeJulius, Carlisle R., Fletcher, R. Brock, Sorets, Alex G., Cherry, Fiona K., Lo, Justin H., Bezold, Mariah G., Francini, Nora, d’Arcy, Richard, Brasuell, Jordan E., Cook, Rebecca S., Duvall, Craig L.
Publikováno v:
In Biomaterials June 2023 297
Autor:
SeaQuest Collaboration, Aidala, C. A., Arrington, J. R., Ayuso, C., Bowen, B. M., Bowen, M. L., Bowling, K. L., Brown, A. W., Brown, C. N., Byrd, R., Carlisle, R. E., Chang, T., Chang, W. -C., Chen, A., Chen, J. -Y., Christian, D. C., Chu, X., Dannowitz, B. P., Daugherity, M., Diefenthaler, M., Dove, J., Durandet, C., Fassi, L. El, Erdos, E., Fox, D. M., Geesaman, D. F., Gilman, R., Goto, Y., Guo, L., Guo, R., Hague, T., Hicks, C. R., Holt, R. J., Isenhower, D., Jiang, X., Katich, J. M., Kerns, B. M., Kinney, E. R., Kitts, N. D., Klein, A., Kleinjan, D., Kras, J., Kudo, Y., Lin, P. -J., Liu, D., Liu, K., Liu, M. X., Lorenzon, W., Makins, N. C. R., Martinez, J. D., McClellan, R. E., McDonald, B., McGaughey, P. L., McNease, S. E., Medeiros, M. M., Miller, B., Miller, A. J., Miyasaka, S., Miyachi, Y., Mooney, I. A., Morton, D. H., Nadim, B., Nagai, K., Nakahara, K., Nakano, K., Nara, S., Obata, S., Peng, J. C., Prasad, S., Puckett, A. J. R., Ramson, B. J., Raymond, R. S., Reimer, P. E., Rubin, J. G., Salinas, R., Sanftl, F., Sawada, S., Sawada, T., Scott, M. B. C., Selensky, L. E., Shibata, T. -A., Shiu, S., Su, D., Tadepalli, A. S., Teo, M., Tice, B. G., Towell, C. L., Towell, R. S., Uemura, S., Wang, S. G., Watson, S., White, N., Wickes, A. B., Wood, M. R., Wu, J., Xi, Z., Ye, Z., Yin, Y.
The SeaQuest spectrometer at Fermilab was designed to detect oppositely-charged pairs of muons (dimuons) produced by interactions between a 120 GeV proton beam and liquid hydrogen, liquid deuterium and solid nuclear targets. The primary physics progr
Externí odkaz:
http://arxiv.org/abs/1706.09990
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Autor:
Richard d’Arcy, Farah El Mohtadi, Nora Francini, Carlisle R. DeJulius, Hyunmoon Back, Arianna Gennari, Mike Geven, Maria Lopez-Cavestany, Zulfiye Yesim Turhan, Fang Yu, Jong Bong Lee, Michael R. King, Leonid Kagan, Craig L. Duvall, Nicola Tirelli
Publikováno v:
D'Arcy, R, El Mohtadi, F, Francini, N, Dejulius, C R, Back, H, Gennari, A, Geven, M, Lopez-Cavestany, M, Turhan, Z Y, Yu, F, Lee, J B, King, M R, Kagan, L, Duvall, C L & Tirelli, N 2022, ' A Reactive Oxygen Species-Scavenging Stealth' Polymer, Poly(thioglycidyl glycerol), Outperforms Poly(ethylene glycol) in Protein Conjugates and Nanocarriers and Enhances Protein Stability to Environmental and Biological Stressors ', Journal of the American Chemical Society, vol. 144, no. 46, pp. 21304-21317 . https://doi.org/10.1021/jacs.2c09232
This study addresses well-known shortcomings of poly(ethylene glycol) (PEG)-based conjugates. PEGylation is by far the most common method employed to overcome immunogenicity and suboptimal pharmacokinetics of, for example, therapeutic proteins but ha
Akademický článek
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Autor:
Ella N. Hoogenboezem, Shrusti S. Patel, Ashley B. Cavnar, Justin H. Lo, Lauren M. Babb, Nora Francini, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook, Craig L. Duvall
Publikováno v:
bioRxiv
The high potential for therapeutic application of siRNAs to silence traditionally undruggable oncogenic drivers remains largely untapped due to the challenges of tumor cell delivery. Here, siRNAs were optimized forin situbinding to albumin through C1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed437d3b4e1884a99c1762f14a4e284b
https://doi.org/10.1101/2023.02.14.528574
https://doi.org/10.1101/2023.02.14.528574