Limited incremental predictive value of the frailty index and other vulnerability measures from routine care data for mortality risk prediction in older patients with COVID-19 in primary care

Autor: Hannah M. la Roi-Teeuw, Kim Luijken, Marieke T. Blom, Jacobijn Gussekloo, Simon P. Mooijaart, Harmke A. Polinder-Bos, Maarten van Smeden, Geert-Jan Geersing, Carline J. van den Dries

Publikováno v: BMC Primary Care, Vol 25, Iss 1, Pp 1-11 (2024)

Abstract Background During the COVID-19 pandemic, older patients in primary care were triaged based on their frailty or assumed vulnerability for poor outcomes, while evidence on the prognostic value of vulnerability measures in COVID-19 patients in

Externí odkaz: https://doaj.org/article/89cce60660574bd49def8834aeb6ea00

Integrated care in patients with atrial fibrillation- a predictive heterogeneous treatment effect analysis of the ALL-IN trial.

Autor: Emmy M Trinks-Roerdink, Geert-Jan Geersing, Carline J van den Dries, Martin E W Hemels, Michiel Rienstra, Isabelle C van Gelder, Maarten van Smeden, David van Klaveren, David M Kent, Frans H Rutten, Sander van Doorn

Publikováno v: PLoS ONE, Vol 18, Iss 10, p e0292586 (2023)

IntroductionIntegrated care is effective in reducing all-cause mortality in patients with atrial fibrillation (AF) in primary care, though time and resource intensive. The aim of the current study was to assess whether integrated care should be direc

Externí odkaz: https://doaj.org/article/24d168f9031d4928b382d759aef18ccf

The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation

Autor: Carline J. van den Dries, Sander van Doorn, Patrick Souverein, Romin Pajouheshnia, Karel G.M. Moons, Arno W. Hoes, Geert-Jan Geersing, Hendrika A. van den Ham

Publikováno v: TH Open, Vol 04, Iss 04, Pp e417-e426 (2020)

Background The benefit of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) on major bleeding was less prominent among atrial fibrillation (AF) patients with polypharmacy in post-hoc randomized controlled trials analyses. Whether

Externí odkaz: https://doaj.org/article/3556874114304f9b9b994ff8d70b6ede

Integrated management of atrial fibrillation in primary care

Autor: Henk J. G. Bilo, Sjef J C M van de Leur, Arif Elvan, Ruud Oudega, Geert-Jan Geersing, Lisa Oude Grave, Carline J. van den Dries, Arno W. Hoes, Karel G.M. Moons, Frans H. Rutten, Sander van Doorn

Publikováno v: European Heart Journal
European Heart Journal, 41(30), 2836-2844. Oxford University Press

Aims To evaluate whether integrated care for atrial fibrillation (AF) can be safely orchestrated in primary care. Methods and results The ALL-IN trial was a cluster randomized, open-label, pragmatic non-inferiority trial performed in primary care pra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9e9e639ca37c17721fcb33e4476ef9
https://research.rug.nl/en/publications/ed83aabd-6a83-45af-bce1-433eb67ac870

Effect of long-term GH replacement therapy on cardiovascular outcomes in isolated GH deficiency compared with multiple pituitary hormone deficiencies: a sub-analysis from the Dutch National Registry of Growth Hormone Treatment in Adults

Autor: Madeleine L. Drent, Christa C. van Bunderen, Martijn W. Heymans, Carline J van den Dries, A.A.M. Franken, H. P. F. Koppeschaar, Aart Jan van der Lely

Publikováno v: European Journal of Endocrinology, 171(2), 151-160. BioScientifica Ltd.
European Journal of Endocrinology, 171(2), 151-160. Bioscientifica Ltd
van Bunderen, C C, van den Dries, C J, Heijmans, M W, Franken, A A M, Koppeschaar, H P F, van der Lely, A J & Drent, M L 2014, ' Effect of long-term GH replacement therapy on cardiovascular outcomes in isolated GH deficiency compared with multiple pituitary hormone deficiencies: a sub-analysis from the Dutch National Registry of Growth Hormone Treatment in Adults ', European Journal of Endocrinology, vol. 171, no. 2, pp. 151-160 . https://doi.org/10.1530/EJE-14-0069

ObjectiveIsolated GH deficiency (IGHD) could provide a model to investigate the influence of GH deficiency per se and the effect of GH replacement therapy without the influence from other pituitary hormone deficiencies or their treatment. The aim of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac345e2c5defee945ccc845fc4a1bfdd
https://pubmed.ncbi.nlm.nih.gov/24801587