Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Carlijn V C, Bouten"'
Autor:
Jing Nie, Sha Lou, Andreas M. A. O. Pollet, Manon vanVegchel, Carlijn V. C. Bouten, Jaap M. J. den Toonder
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Organ‐on‐a‐chip (OOC) models based on microfluidic technology are increasingly used to obtain mechanistic insight into (patho)physiological processes in humans, and they hold great promise for application in drug development and regene
Externí odkaz:
https://doaj.org/article/66969f338d874b90ae17e41e205885da
Autor:
Josephina J. H. M. Smits, Atze van der Pol, Marie José Goumans, Carlijn V. C. Bouten, Ignasi Jorba
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The dynamic nature of the extracellular matrix (ECM), particularly its stiffness, plays a pivotal role in cellular behavior, especially after myocardial infarction (MI), where cardiac fibroblasts (cFbs) are key in ECM remodeling. This study explores
Externí odkaz:
https://doaj.org/article/4bd0c4fb846e400587fcb09ea42e9ca1
Autor:
Maria J Hagelaars, Milica Nikolic, Maud Vermeulen, Sylvia Dekker, Carlijn V C Bouten, Sandra Loerakker
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1012140 (2024)
Apical-basal polarization in renal epithelial cells is crucial to renal function and an important trigger for tubule formation in kidney development. Loss of polarity can induce epithelial-to-mesenchymal transition (EMT), which can lead to kidney pat
Externí odkaz:
https://doaj.org/article/e946d945acc148e88ab77435a6fc364c
Autor:
Annemijn Vis, Bente J. de Kort, Wojciech Szymczyk, Jan Willem van Rijswijk, Sylvia Dekker, Rob Driessen, Niels Wijkstra, Paul F. Gründeman, Hans W. M. Niessen, Henk M. Janssen, Serge H. M. Söntjens, Patricia Y. W. Dankers, Anthal I. P. M. Smits, Carlijn V. C. Bouten, Jolanda Kluin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is t
Externí odkaz:
https://doaj.org/article/cd42ea311b8e4f6dbdd34aa53ab1b497
Autor:
Janine Grolleman, Nicole C. A. van Engeland, Minahil Raza, Sepinoud Azimi, Vito Conte, Cecilia M. Sahlgren, Carlijn V. C. Bouten
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Recent experimental evidence indicates a role for the intermediate filament vimentin in regulating cellular mechanical homeostasis, but its precise contribution remains to be discovered. Mechanical homeostasis requires a balanced bi-directio
Externí odkaz:
https://doaj.org/article/7cfb17417fde4104938a406127e6d002
Autor:
Cas van der Putten, Gozde Sahin, Rhiannon Grant, Mirko D’Urso, Stefan Giselbrecht, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 402 (2024)
In the event of disease or injury, restoration of the native organization of cells and extracellular matrix is crucial for regaining tissue functionality. In the cornea, a highly organized collagenous tissue, keratocytes can align along the anisotrop
Externí odkaz:
https://doaj.org/article/8b5f5e14ad0645b0908cea1b34f7b7f6
Autor:
Dylan Mostert, Janine Grolleman, Mark C. van Turnhout, Bart G. W. Groenen, Vito Conte, Cecilia M. Sahlgren, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Ventral actin stress fibers (SFs) are a subset of actin SFs that begin and terminate at focal adhesion (FA) complexes. Ventral SFs can transmit forces from and to the extracellular matrix and serve as a prominent mechanosensing and mechanotransductio
Externí odkaz:
https://doaj.org/article/5fdea6403ceb4c3795be383693e0ac1f
Autor:
Paul J. Besseling, Merle M. Krebber, Joost O. Fledderus, Martin Teraa, Krista den Ouden, Melanie van de Kaa, Petra M. de Bree, Aurelie Serrero, Carlijn V. C. Bouten, Patricia Y. W. Dankers, Martijn A. J. Cox, Marianne C. Verhaar
Publikováno v:
APL Bioengineering, Vol 7, Iss 2, Pp 026107-026107-12 (2023)
Vascular in situ tissue engineering encompasses a single-step approach with a wide adaptive potential and true off-the-shelf availability for vascular grafts. However, a synchronized balance between breakdown of the scaffold material and neo-tissue f
Externí odkaz:
https://doaj.org/article/576e9e71f08d4945ac29a81368da757c
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A method is developed to engineer cerebral tissues with intact 3D neuronal networks, mimicking neuropathological signatures such as the propagation of epileptiform discharges, using a multi-chambered tissue culture chip.
Externí odkaz:
https://doaj.org/article/aa2bd7dbb93d4296b77d0feb06c010eb
Autor:
Suzanne E. Koch, Bente J. de Kort, Noud Holshuijsen, Hannah F. M. Brouwer, Dewy C. van der Valk, Patricia Y. W. Dankers, Judith A. K. R. van Luijk, Carlijn R. Hooijmans, Rob B. M. de Vries, Carlijn V. C. Bouten, Anthal I. P. M. Smits
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Vascular in situ tissue engineering (TE) is an approach that uses bioresorbable grafts to induce endogenous regeneration of damaged blood vessels. The evaluation of newly developed in situ TE vascular grafts heavily relies on animal experime
Externí odkaz:
https://doaj.org/article/26f98a3e3a7348fca29e9a6556fa803f