Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Carlie L. Cullen"'
Autor:
Natasha Stevens, Chigozie Ezegbe, Valery Fuh-Ngwa, Kalina Makowiecki, Amin Zarghami, Phuong Tram Nguyen, Julie Sansom, Kate Smith, Laura L. Laslett, Meg Denham, Carlie L. Cullen, Michael H. Barnett, Mark R. Hinder, Monique Breslin, Kaylene M. Young, Bruce V. Taylor
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background Multiple sclerosis (MS) is a chronic neurological condition and the leading cause of non-traumatic disability in young adults. MS pathogenesis leads to the death of oligodendrocytes, demyelination, and progressive central nervous
Externí odkaz:
https://doaj.org/article/f63bb6c9caf244c59917e3eca9caacc5
Autor:
Kalina Makowiecki, Natasha Stevens, Carlie L. Cullen, Amin Zarghami, Phuong Tram Nguyen, Lewis Johnson, Jennifer Rodger, Mark R. Hinder, Michael Barnett, Kaylene M. Young, Bruce V. Taylor
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease, characterised by oligodendrocyte death and demyelination. Oligodendrocyte progenitor cells can differentiate into new replacement oligodendrocytes; however,
Externí odkaz:
https://doaj.org/article/cc7b2f51d6e840e7a9025424537ce232
Autor:
Yilan Zhen, Carlie L. Cullen, Raphael Ricci, Benjamin S. Summers, Sakina Rehman, Zubair M. Ahmed, Antoinette Y. Foster, Ben Emery, Robert Gasperini, Kaylene M. Young
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-21 (2022)
Protocadherin 15 promotes lamellipodial and filopodial dynamics in oligodendrocyte progenitor cells by regulating Cdc42-Arp2/3 activity, but also suppresses ERK1/2 phosphorylation to reduce proliferation.
Externí odkaz:
https://doaj.org/article/5c6fb3dbd66a477395c3c0828c084902
Autor:
Loic Auderset, Kimberley A. Pitman, Carlie L. Cullen, Renee E. Pepper, Bruce V. Taylor, Lisa Foa, Kaylene M. Young
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Low-density lipoprotein receptor-related protein 1 (LRP1) is a large, endocytic cell surface receptor that is highly expressed by oligodendrocyte progenitor cells (OPCs) and LRP1 expression is rapidly downregulated as OPCs differentiate into oligoden
Externí odkaz:
https://doaj.org/article/a80eab967aa7467ab367559a81457003
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Oligodendrocyte progenitor cells (OPCs) are immature cells in the central nervous system (CNS) that can rapidly respond to changes within their environment by modulating their proliferation, motility and differentiation. OPCs differentiate into myeli
Externí odkaz:
https://doaj.org/article/e37f509f93b64a8c8448092753590e15
Autor:
Carlie L. Cullen, Kaylene M. Young
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 15-16 (2017)
Externí odkaz:
https://doaj.org/article/c3a8e8ee7b7f44a0bf84b7a5a1b1f19a
Publikováno v:
Seminars in Cell & Developmental Biology. 118:14-23
During cortical development and throughout adulthood, oligodendrocytes add myelin internodes to glutamatergic projection neurons and GABAergic inhibitory neurons. In addition to directing node of Ranvier formation, to enable saltatory conduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adab0d839a8a4e7c47fe51e46f8747b
https://doi.org/10.1016/j.semcdb.2021.03.017
https://doi.org/10.1016/j.semcdb.2021.03.017
Autor:
Renee E Pepper, Megan O'Rourke, Carlie L. Cullen, Loic Auderset, Shannon J Beasley, Kaylene M. Young, Robert Gasperini, Yilan Zhen
Publikováno v:
Glia
Primary cilia are small microtubule‐based organelles capable of transducing signals from growth factor receptors embedded in the cilia membrane. Developmentally, oligodendrocyte progenitor cells (OPCs) express genes associated with primary cilia as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d36fe7c87b3b28f73640dca5d1f57af
https://doi.org/10.1002/glia.23957
https://doi.org/10.1002/glia.23957
Autor:
Carlie L Cullen, Kaylene M Young
Publikováno v:
Frontiers in Neural Circuits, Vol 10 (2016)
Transcranial magnetic stimulation (TMS) is widely used in the clinic, and while it has a direct effect on neuronal excitability, the beneficial effects experienced by patients are likely to include the indirect activation of other cell types. Researc
Externí odkaz:
https://doaj.org/article/860f6779aed747868601ea46b95414b9
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0155878 (2016)
The low density lipoprotein-receptor related protein 1 (LRP1) is a large endocytic cell surface receptor that is known to interact with a variety of ligands, intracellular adaptor proteins and other cell surface receptors to regulate cellular behavio
Externí odkaz:
https://doaj.org/article/c67dbd796ab5469bbb294f1096ee53b1