Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carlie L. Charron"'
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 27(5)
The AgI -promoted reaction of thiolactams with N-Boc amino acids yields an N-(α-aminoacyl) lactam that can rearrange through an acyl transfer process. Boc-deprotection results in convergence to the ring-expanded adduct, thereby facilitating an overa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0620349cf1b64b3b7a3ecc167ade39
https://pubmed.ncbi.nlm.nih.gov/33289186
https://pubmed.ncbi.nlm.nih.gov/33289186
Publikováno v:
Organic & Biomolecular Chemistry. 17:598-608
The C-X-C chemokine receptor 4 (CXCR4) has been shown to be overexpressed in at least 23 types of cancer, including prostate cancer which has been shown to have a significant distinction of expression rates between cancerous compared to healthy or be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cd72ebab3dfe1be5ced6fec6e2a918
https://doi.org/10.1039/c8ob01947a
https://doi.org/10.1039/c8ob01947a
Publikováno v:
MedChemComm. 9:1761-1767
The ghrelin receptor is a member of the growth hormone secretagogue receptor (GHS-R) family and is present at low concentrations in tissues such as the brain, kidney, cardiovascular system, and prostate. The ghrelin receptor plays an important role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60ceda1165c55f9cd2e32d7be1f25cd8
https://doi.org/10.1039/c8md00210j
https://doi.org/10.1039/c8md00210j
Autor:
Michael S. Kovacs, Leonard G. Luyt, Jinqiang Hou, Mark S. McFarland, Carlie L. Charron, Savita Dhanvantari
Publikováno v:
Journal of Medicinal Chemistry. 60:7256-7266
The ghrelin receptor, also known as the growth hormone secretagogue receptor 1a (GHS-R1a), is a G-protein-coupled receptor that is differentially expressed in healthy tissue and several cancers, including prostate, testicular, and ovarian. Selectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9cf288cf9137e29c6c7592da96b468
https://doi.org/10.1021/acs.jmedchem.7b00164
https://doi.org/10.1021/acs.jmedchem.7b00164
Publikováno v:
Tetrahedron Letters. 57:4119-4127
This digest highlights recent developments in the field of molecular imaging of cancer using peptide-based targeting entities. Syntheses of novel radiolabelled prosthetic groups and new radiolabelled peptide conjugates are highlighted. This review fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f9765c7fa71616e7f3cab90d36863b
https://doi.org/10.1016/j.tetlet.2016.07.083
https://doi.org/10.1016/j.tetlet.2016.07.083
Autor:
William L, Turnbull, Lihai, Yu, Emily, Murrell, Mark, Milne, Carlie L, Charron, Leonard G, Luyt
Publikováno v:
Organicbiomolecular chemistry. 17(3)
The C-X-C chemokine receptor 4 (CXCR4) has been shown to be overexpressed in at least 23 types of cancer, including prostate cancer which has been shown to have a significant distinction of expression rates between cancerous compared to healthy or be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5be850d7d8992f8e382c03c7515332bd
https://pubmed.ncbi.nlm.nih.gov/30574973
https://pubmed.ncbi.nlm.nih.gov/30574973
Autor:
Stanley C, Xie, David L, Gillett, Natalie J, Spillman, Christopher, Tsu, Madeline R, Luth, Sabine, Ottilie, Sandra, Duffy, Alexandra E, Gould, Paul, Hales, Benjamin A, Seager, Carlie L, Charron, Frank, Bruzzese, Xiaofeng, Yang, Xiansi, Zhao, Shih-Chung, Huang, Craig A, Hutton, Jeremy N, Burrows, Elizabeth A, Winzeler, Vicky M, Avery, Lawrence R, Dick, Leann, Tilley
Publikováno v:
Journal of Medicinal Chemistry
The Plasmodium proteasome represents a potential antimalarial drug target for compounds with activity against multiple life cycle stages. We screened a library of human proteasome inhibitors (peptidyl boronic acids) and compared activities against pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baa6b25d4621602ea8b6561b2d264873
https://pubmed.ncbi.nlm.nih.gov/30373366
https://pubmed.ncbi.nlm.nih.gov/30373366
Autor:
Leonard G. Luyt, Jennifer L. Hickey, T. K. Nsiama, Carlie L. Charron, William L. Turnbull, D. R. Cruickshank
Publikováno v:
Natural Product Reports. 33:761-800
Covering: up to the end of 2015.Peptides are naturally occurring compounds that play an important role in all living systems and are responsible for a range of essential functions. Peptide receptors have been implicated in disease states such as onco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8f23d8c21aa028271d420dab914fc0
https://doi.org/10.1039/c5np00083a
https://doi.org/10.1039/c5np00083a
Autor:
Derek Wu, Alice Tan, Tyler Lalonde, Rebecca McGirr, Leonard G. Luyt, Carlie L. Charron, Shirley Hu, Subrata Chakrabarti, Savita Dhanvantari, Edith Arany, Rebecca Sullivan
Publikováno v:
Paediatrics Publications
Journal of the Endocrine Society
Journal of the Endocrine Society
Ghrelin and its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), are present in cardiac tissue. Activation of GHSR1a by ghrelin promotes cardiomyocyte contractility and survival, and changes in myocardial GHSR1a and circulating ghrelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21392331358f060f5d6a6879d5505ee
https://ir.lib.uwo.ca/context/paedpub/article/1677/viewcontent/js.2017_00433.pdf
https://ir.lib.uwo.ca/context/paedpub/article/1677/viewcontent/js.2017_00433.pdf
Publikováno v:
ChemInform. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac91cd49ca86dd9b8dd4dc2ae0561ff
https://doi.org/10.1002/chin.201642277
https://doi.org/10.1002/chin.201642277