Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Carlie L Cullen"'
Autor:
Natasha Stevens, Chigozie Ezegbe, Valery Fuh-Ngwa, Kalina Makowiecki, Amin Zarghami, Phuong Tram Nguyen, Julie Sansom, Kate Smith, Laura L. Laslett, Meg Denham, Carlie L. Cullen, Michael H. Barnett, Mark R. Hinder, Monique Breslin, Kaylene M. Young, Bruce V. Taylor
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background Multiple sclerosis (MS) is a chronic neurological condition and the leading cause of non-traumatic disability in young adults. MS pathogenesis leads to the death of oligodendrocytes, demyelination, and progressive central nervous
Externí odkaz:
https://doaj.org/article/f63bb6c9caf244c59917e3eca9caacc5
Autor:
Carlie L Cullen, Kaylene M Young
Publikováno v:
Frontiers in Neural Circuits, Vol 10 (2016)
Transcranial magnetic stimulation (TMS) is widely used in the clinic, and while it has a direct effect on neuronal excitability, the beneficial effects experienced by patients are likely to include the indirect activation of other cell types. Researc
Externí odkaz:
https://doaj.org/article/860f6779aed747868601ea46b95414b9
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0155878 (2016)
The low density lipoprotein-receptor related protein 1 (LRP1) is a large endocytic cell surface receptor that is known to interact with a variety of ligands, intracellular adaptor proteins and other cell surface receptors to regulate cellular behavio
Externí odkaz:
https://doaj.org/article/c67dbd796ab5469bbb294f1096ee53b1
Autor:
Megan O'Rourke, Carlie L Cullen, Loic Auderset, Kimberley A Pitman, Daniela Achatz, Robert Gasperini, Kaylene M Young
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162858 (2016)
In the central nervous system (CNS) platelet derived growth factor receptor alpha (PDGFRα) is expressed exclusively by oligodendrocyte progenitor cells (OPCs), making the Pdgfrα promoter an ideal tool for directing transgene expression in this cell
Externí odkaz:
https://doaj.org/article/15dcc914951e404485ffac793f62a0ac
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101482 (2014)
Consumption of alcohol during pregnancy can have detrimental impacts on the developing hippocampus, which can lead to deficits in learning and memory function. Although high levels of alcohol exposure can lead to severe deficits, there is a lack of r
Externí odkaz:
https://doaj.org/article/97f7766ffdb24abab1ec52db08458669
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54924 (2013)
Prenatal exposure to high levels of alcohol is strongly associated with poor cognitive outcomes particularly in relation to learning and memory. It is also becoming more evident that anxiety disorders and anxiety-like behaviour can be associated with
Externí odkaz:
https://doaj.org/article/f1e53a7484534aa8a7b349b6b8c6d2f4
Autor:
Kalina Makowiecki, Natasha Stevens, Carlie L. Cullen, Amin Zarghami, Phuong Tram Nguyen, Lewis Johnson, Jennifer Rodger, Mark R. Hinder, Michael Barnett, Kaylene M. Young, Bruce V. Taylor
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease, characterised by oligodendrocyte death and demyelination. Oligodendrocyte progenitor cells can differentiate into new replacement oligodendrocytes; however,
Externí odkaz:
https://doaj.org/article/cc7b2f51d6e840e7a9025424537ce232
Autor:
Yilan Zhen, Carlie L. Cullen, Raphael Ricci, Benjamin S. Summers, Sakina Rehman, Zubair M. Ahmed, Antoinette Y. Foster, Ben Emery, Robert Gasperini, Kaylene M. Young
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-21 (2022)
Protocadherin 15 promotes lamellipodial and filopodial dynamics in oligodendrocyte progenitor cells by regulating Cdc42-Arp2/3 activity, but also suppresses ERK1/2 phosphorylation to reduce proliferation.
Externí odkaz:
https://doaj.org/article/5c6fb3dbd66a477395c3c0828c084902
Publikováno v:
Seminars in Cell & Developmental Biology. 118:14-23
During cortical development and throughout adulthood, oligodendrocytes add myelin internodes to glutamatergic projection neurons and GABAergic inhibitory neurons. In addition to directing node of Ranvier formation, to enable saltatory conduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adab0d839a8a4e7c47fe51e46f8747b
https://doi.org/10.1016/j.semcdb.2021.03.017
https://doi.org/10.1016/j.semcdb.2021.03.017
Autor:
Renee E Pepper, Megan O'Rourke, Carlie L. Cullen, Loic Auderset, Shannon J Beasley, Kaylene M. Young, Robert Gasperini, Yilan Zhen
Publikováno v:
Glia
Primary cilia are small microtubule‐based organelles capable of transducing signals from growth factor receptors embedded in the cilia membrane. Developmentally, oligodendrocyte progenitor cells (OPCs) express genes associated with primary cilia as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d36fe7c87b3b28f73640dca5d1f57af
https://doi.org/10.1002/glia.23957
https://doi.org/10.1002/glia.23957