Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carlie J. M. de Vries"'
Autor:
Jayron J. Habibe, Ulrika Boulund, Maria P. Clemente-Olivo, Carlie J. M. de Vries, Etto C. Eringa, Max Nieuwdorp, Bart Ferwerda, Koos Zwinderman, Bert-Jan H. van den Born, Henrike Galenkamp, Daniel H. van Raalte
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4332 (2023)
Type 2 diabetes mellitus (T2D) is a prevalent disease often accompanied by the occurrence of dyslipidemia. Four and a half LIM domains 2 (FHL2) is a scaffolding protein, whose involvement in metabolic disease has recently been demonstrated. The assoc
Externí odkaz:
https://doaj.org/article/0f4a37c545a2467dbc45b02802214713
Autor:
Lejla Medzikovic, Hylja Heese, Pieter B. van Loenen, Cindy P. A. A. van Roomen, Ingeborg B. Hooijkaas, Vincent M. Christoffels, Esther E. Creemers, Carlie J. M. de Vries, Vivian de Waard
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1600 (2021)
Fibrosis is a hallmark of adverse cardiac remodeling, which promotes heart failure, but it is also an essential repair mechanism to prevent cardiac rupture, signifying the importance of appropriate regulation of this process. In the remodeling heart,
Externí odkaz:
https://doaj.org/article/39513847d0d6451e869bd58e23897a43
Autor:
Jayron J. Habibe, Maria P. Clemente-Olivo, Torsten P. M. Scheithauer, Elena Rampanelli, Hilde Herrema, Mariska Vos, Arnout Mieremet, Max Nieuwdorp, Daniel H. van Raalte, Etto C. Eringa, Carlie J. M. de Vries
Publikováno v:
Diabetologia, 65(10):s00125-022-05750-1, 1721-1733. Springer, Cham
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Aims/hypothesis The general population is ageing, involving an enhanced incidence of chronic diseases such as type 2 diabetes. With ageing, DNA methylation of FHL2 increases, as well as expression of the four and a half LIM domains 2 (FHL2) protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1a0b6b39ebcc4c030dcc7270ac9cd3
https://doi.org/10.1007/s00125-022-05750-1
https://doi.org/10.1007/s00125-022-05750-1
Autor:
Thijs W H Pols, Teresa Puchner, H Inci Korkmaz, Mariska Vos, Maarten R Soeters, Carlie J M de Vries
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176715 (2017)
Bile acids are established signaling molecules next to their role in the intestinal emulsification and uptake of lipids. We here aimed to identify a potential interaction between bile acids and CD4+ Th cells, which are central in adaptive immune resp
Externí odkaz:
https://doaj.org/article/ea3e342f404245548b1732c20e8621b8
Autor:
Maria P, Clemente-Olivo, Miguel, Hernández-Quiles, Rinske, Sparrius, Miesje M, van der Stoel, Vera, Janssen, Jayron, Habibe, Janny, van den Burg, Aldo, Jongejan, Paula Sobrevals, Alcaraz, Robert, van Es, Harmjan, Vos, Eric, Kalkhoven, Carlie J M, de Vries
Publikováno v:
Cellular Signalling. 104:110587
The LIM-domain-only protein FHL2 is a modulator of signal transduction and has been shown to direct the differentiation of mesenchymal stem cells towards osteoblast and myocyte phenotypes. We hypothesized that FHL2 may simultaneously interfere with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f596e279469ae781694e1dc398a5e107
https://doi.org/10.1016/j.cellsig.2023.110587
https://doi.org/10.1016/j.cellsig.2023.110587
Autor:
Anouk A J Hamers, Laura van Dam, José M Teixeira Duarte, Mariska Vos, Goran Marinković, Claudia M van Tiel, Sybren L Meijer, Anne-Marieke van Stalborch, Stephan Huveneers, Anje A Te Velde, Wouter J de Jonge, Carlie J M de Vries
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133598 (2015)
Nuclear receptor Nur77, also referred to as NR4A1 or TR3, plays an important role in innate and adaptive immunity. Nur77 is crucial in regulating the T helper 1/regulatory T-cell balance, is expressed in macrophages and drives M2 macrophage polarizat
Externí odkaz:
https://doaj.org/article/4b9b9f329923409a8e16c7fe047764c6
Autor:
Aart C Strang, Menno L W Knetsch, Leo H Koole, Robbert J de Winter, Allard C van der Wal, Carlie J M de Vries, Paul P Tak, Radjesh J Bisoendial, Erik S G Stroes, Joris I Rotmans
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122836 (2015)
Since high-density lipoprotein (HDL) has pro-endothelial and anti-thrombotic effects, a HDL recruiting stent may prevent restenosis. In the present study we address the functional characteristics of an apolipoprotein A-I (ApoA-I) antibody coating in
Externí odkaz:
https://doaj.org/article/354191a2f30a4e808cd1418e43f51f8b
Autor:
Matthijs S Ruiter, Claudia M van Tiel, Albert Doornbos, Goran Marinković, Aart C Strang, Nico J M Attevelt, Vivian de Waard, Robbert J de Winter, Rob Steendam, Carlie J M de Vries
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138459 (2015)
The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (
Externí odkaz:
https://doaj.org/article/03a0521f57254233ae1b676b203c4f4f
Autor:
Kondababu Kurakula, Mariska Vos, Iker Otermin Rubio, Goran Marinković, Reinhard Buettner, Lukas C Heukamp, Jan Stap, Vivian de Waard, Claudia M van Tiel, Carlie J M de Vries
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94931 (2014)
The LIM-only protein FHL2, also known as DRAL or SLIM3, has a function in fine-tuning multiple physiological processes. FHL2 is expressed in the vessel wall in smooth muscle cells (SMCs) and endothelial cells and conflicting data have been reported o
Externí odkaz:
https://doaj.org/article/26b213cef63945599aa7e3cec543a1a3
Autor:
Romy Franken, Stijntje Hibender, Alexander W den Hartog, Teodora Radonic, Carlie J M de Vries, Aeilko H Zwinderman, Maarten Groenink, Barbara J M Mulder, Vivian de Waard
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107221 (2014)
AIMS:Patients with Marfan syndrome have an increased risk of life-threatening aortic complications, mostly preceded by aortic dilatation. In the FBN1(C1039G/+) Marfan mouse model, losartan decreases aortic root dilatation. We recently confirmed this
Externí odkaz:
https://doaj.org/article/291beb41452c49dbb62569b3b81539e6