Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Carlie A. Delaine"'
Autor:
Shee Chee Ong, Alessia Belgi, Allanah L. Merriman, Carlie A. Delaine, Bianca van Lierop, Sofianos Andrikopoulos, Andrea J. Robinson, Briony E. Forbes
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The mechanisms by which insulin activates the insulin receptor to promote metabolic processes and cellular growth are still not clear. Significant advances have been gained from recent structural studies in understanding how insulin binds to its rece
Externí odkaz:
https://doaj.org/article/a3aaeb206dde409cae3f877af9454a36
Autor:
Yibin Xu, Geoffrey K.-W. Kong, John G. Menting, Mai B. Margetts, Carlie A. Delaine, Lauren M. Jenkin, Vladislav V. Kiselyov, Pierre De Meyts, Briony E. Forbes, Michael C. Lawrence
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The human type 1 insulin-like growth factor receptor (IGF-1R) is important for normal human growth and development. Here, the authors present the crystal structures of the IGF-1R ectodomain both in its apo form and in complex with its ligand insulin-
Externí odkaz:
https://doaj.org/article/0ffae8d861b845cfaea6faecbb96119f