Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carley Fowler"'
Autor:
Justin A. Guerrero, Dorota D. Klysz, Yiyun Chen, Meena Malipatlolla, Jameel Lone, Carley Fowler, Lucille Stuani, Audre May, Malek Bashti, Peng Xu, Jing Huang, Basil Michael, Kévin Contrepois, Shaurya Dhingra, Chris Fisher, Katrin J. Svensson, Kara L. Davis, Maya Kasowski, Steven A. Feldman, Elena Sotillo, Crystal L. Mackall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The intensive nutrient requirements needed to sustain T cell activation and proliferation, combined with competition for nutrients within the tumor microenvironment, raise the prospect that glucose availability may limit CAR-T cell function.
Externí odkaz:
https://doaj.org/article/83e1ea5811734dc0b264ba4b71908511
Autor:
Hyatt Balke-Want, Vimal Keerthi, Nikolaos Gkitsas, Andrew G. Mancini, Gavin L. Kurgan, Carley Fowler, Peng Xu, Xikun Liu, Kyle Asano, Sunny Patel, Christopher J. Fisher, Annie K. Brown, Ramya H. Tunuguntla, Shabnum Patel, Elena Sotillo, Crystal L. Mackall, Steven A. Feldman
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Chimeric Antigen Receptor (CAR) T cells are now standard of care (SOC) for some patients with B cell and plasma cell malignancies and could disrupt the therapeutic landscape of solid tumors. However, access to CAR-T cells is not a
Externí odkaz:
https://doaj.org/article/30c152e41bad4daaa1a6be153fb3bf6c
Autor:
Katalin Sandor, Peng Xu, Jing Huang, Steven A Feldman, Nikolaos Gkitsas, Crystal L Mackall, Bence Daniel, Dorota Klysz, Malek Bashti, Elena Sotillo, Ansuman T Satpathy, Carley Fowler, Meena Malipatlolla, Lucille Stuani, Katherine A Freitas, Stefanie Meier, Louai Labanieh, Amaury Leruste, Janette Mata-Alcazar, Vimal Keerthi, Justin A Guerrero, Chris Fisher, Sunny Patel, Kyle Asano, Shabnum Patel, Kara L Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ac586e86c0cd4992806758a3b9aa88b7
Abstract 1158: Inosine endows CAR T cells with features of increased stemness and anti-tumor potency
Autor:
Dorota Klysz, Katie Freitas, Meena Malipatlolla, Stefanie Maier, Carley Fowler, Louai Labanieh, Lucille Stuani, Bence Daniel, Katalin Sandor, Peng Xu, Jing Huang, Amaury Leruste, Vimal Keerthi, Nikolaos Gkitsas, Shabnum Patel, Justin Arredondo-Guerrero, Chris Fisher, Kyle Asano, Sunny Patel, Ansuman Satpathy, Kara Davis, Elena Sotillo, Steven Feldman, Crystal Mackall
Publikováno v:
Cancer Research. 83:1158-1158
Chimeric antigen receptors (CARs) are synthetic receptors that link an extracellular tumor specific domain to intracellular signaling domains. Despite of remarkable results against refractory B cell malignancies, intense effort is underway to augment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a991d4648001aeaef8e313501541603
https://doi.org/10.1158/1538-7445.am2023-1158
https://doi.org/10.1158/1538-7445.am2023-1158