Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells.

Autor: Gerdes P; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Lim SM; Department of Anatomy & Developmental Biology, Monash University, Melbourne, VIC, 3800, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, VIC, 3800, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, 3800, Australia., Ewing AD; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Larcombe MR; Department of Anatomy & Developmental Biology, Monash University, Melbourne, VIC, 3800, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, VIC, 3800, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, 3800, Australia., Chan D; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Sanchez-Luque FJ; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia.; GENYO. Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research, PTS, Granada, 18016, Spain., Walker L; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Carleton AL; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., James C; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Knaupp AS; Department of Anatomy & Developmental Biology, Monash University, Melbourne, VIC, 3800, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, VIC, 3800, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, 3800, Australia., Carreira PE; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia., Nefzger CM; Department of Anatomy & Developmental Biology, Monash University, Melbourne, VIC, 3800, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, VIC, 3800, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, 3800, Australia., Lister R; Australian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, WA, 6009, Australia.; Harry Perkins Institute of Medical Research, Perth, WA, 6009, Australia., Richardson SR; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia. sandra.richardson@mater.uq.edu.au., Polo JM; Department of Anatomy & Developmental Biology, Monash University, Melbourne, VIC, 3800, Australia. jose.polo@monash.edu.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, VIC, 3800, Australia. jose.polo@monash.edu.; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, 3800, Australia. jose.polo@monash.edu.; Adelaide Centre for Epigenetics and The South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia. jose.polo@monash.edu., Faulkner GJ; Mater Research Institute - University of Queensland, TRI Building, Woolloongabba, QLD, 4102, Australia. faulknergj@gmail.com.; Queensland Brain Institute, University of Queensland, Brisbane, QLD, 4072, Australia. faulknergj@gmail.com.

Publikováno v: Nature communications [Nat Commun] 2022 Dec 03; Vol. 13 (1), pp. 7470. Date of Electronic Publication: 2022 Dec 03.