Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carles Canto"'
Autor:
Angelique Cercillieux, Joanna Ratajczak, Magali Joffraud, José Luis Sanchez-Garcia, Guillaume Jacot, Alix Zollinger, Sylviane Métairon, Judith Giroud-Gerbetant, Marie Rumpler, Eleonora Ciarlo, Miriam Valera-Alberni, Audrey Sambeat, Carles Canto
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101605- (2022)
Objective: Disturbances in NAD+ metabolism have been described as a hallmark for multiple metabolic and age-related diseases, including type 2 diabetes. While alterations in pancreatic β-cell function are critical determinants of whole-body glucose
Externí odkaz:
https://doaj.org/article/945b64715a904374bce76583c128706e
Autor:
Judith Giroud-Gerbetant, Magali Joffraud, Maria Pilar Giner, Angelique Cercillieux, Simona Bartova, Mikhail V. Makarov, Rubén Zapata-Pérez, José L. Sánchez-García, Riekelt H. Houtkooper, Marie E. Migaud, Sofia Moco, Carles Canto
Publikováno v:
Molecular Metabolism, Vol 30, Iss , Pp 192-202 (2019)
Objective: A decay in intracellular NAD+ levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD+ precursors can prevent, alleviate, or even reverse multiple metabolic complica
Externí odkaz:
https://doaj.org/article/6c4c170dedb84391bff1d462c0934a35
Autor:
Audrey Sambeat, Joanna Ratajczak, Magali Joffraud, José L. Sanchez-Garcia, Maria P. Giner, Armand Valsesia, Judith Giroud-Gerbetant, Miriam Valera-Alberni, Angelique Cercillieux, Marie Boutant, Sameer S. Kulkarni, Sofia Moco, Carles Canto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nicotinamide adenine dinucleotide (NAD+) sustains cellular energy metabolism, functions as a substrate of Sirt and PARP enzymes, and its supplementation is explored therapeutically in aging and other contexts. Here the authors provide insight into th
Externí odkaz:
https://doaj.org/article/d868646ab078447ea44fb258c12312d5
Autor:
Carles Canto
Publikováno v:
Metabolites, Vol 12, Iss 7, p 630 (2022)
The last decade has seen a strong proliferation of therapeutic strategies for the treatment of metabolic and age-related diseases based on increasing cellular NAD+ bioavailability. Among them, the dietary supplementation with NAD+ precursors—classi
Externí odkaz:
https://doaj.org/article/8e1493d9dc7e427687b6de663c874bcf
Autor:
Miriam Valera-Alberni, Carles Canto
Publikováno v:
Cell Stress, Vol 2, Iss 10, Pp 253-274 (2018)
Mitochondria undergo continuous challenges in the course of their life, from their generation to their degradation. These challenges include the management of reactive oxygen species, the proper assembly of mitochondrial respiratory complexes and the
Externí odkaz:
https://doaj.org/article/379be351de33454093b94721fa0ba7a5
Autor:
Maria Pilar Giner, Stefan Christen, Simona Bartova, Mikhail V. Makarov, Marie E. Migaud, Carles Canto, Sofia Moco
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10598 (2021)
Nicotinamide adenine dinucleotide (NAD+) and its reduced form (NADH) are coenzymes employed in hundreds of metabolic reactions. NAD+ also serves as a substrate for enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs) and ADP-ribosyl cyclase
Externí odkaz:
https://doaj.org/article/0820e414ecc345bd87701d172f06110c
Autor:
Rachel S. Fletcher, Joanna Ratajczak, Craig L. Doig, Lucy A. Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S. Elhassan, Philip Redpath, Marie E. Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G. Lavery
Publikováno v:
Molecular Metabolism, Vol 6, Iss 8, Pp 819-832 (2017)
Objective: Augmenting nicotinamide adenine dinucleotide (NAD+) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) ap
Externí odkaz:
https://doaj.org/article/31c59e382804472ca4d15f33085dd592
Autor:
Radiana Ferrero, Pernille Yde Rainer, Julie Russeil, Magda Zachara, Joern Pezoldt, Guido van Mierlo, Vincent Gardeux, Wouter Saelens, Daniel Alpern, Lucie Favre, Styliani Mantziari, Tobias Zingg, Nelly Pitteloud, Michel Suter, Maurice Matter, Carles Canto, Bart Deplancke
Adipose tissue plasticity is orchestrated by molecularly and functionally diverse cells within the stromal vascular fraction (SVF). While several mouse and human adipose SVF cellular subpopulations have now been identified, we still lack an understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf98498e859e835f2fb45b565215bc24
https://doi.org/10.1101/2023.05.01.538871
https://doi.org/10.1101/2023.05.01.538871
Autor:
Carles, Canto
Publikováno v:
Metabolites. 12(7)
The last decade has seen a strong proliferation of therapeutic strategies for the treatment of metabolic and age-related diseases based on increasing cellular NAD
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(8)
Alterations in cellular nicotinamide adenine dinucleotide (NAD