Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Carles Barceló"'
Autor:
Juan González-Moreno, Álvaro Gragera-Martínez, Adrián Rodríguez, Cristina Borrachero-Garro, Sandra García-Garrido, Carles Barceló, Ana Manovel-Sánchez, Maria Antonia Ribot-Sansó, Lesly Ibargüen-González, Rosa Gomila, Francisco Muñoz-Beamud, Inés Losada-López, Eugenia Cisneros-Barroso
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Early identification of ATTRv amyloidosis disease onset is still often delayed due to the lack of validated biomarkers of this disease. Light chain neurofilament (NfL) have shown promising results in early diagnosis in this disease, but data
Externí odkaz:
https://doaj.org/article/f491e56deaff4e268c5c6c466f3a8c66
Autor:
Aadil Javed, Gianluca Malagraba, Mahdieh Yarmohammadi, Catalina M. Perelló-Reus, Carles Barceló, Teresa Rubio-Tomás
Publikováno v:
Future Pharmacology, Vol 2, Iss 3, Pp 214-237 (2022)
Mitosis entails mechanistic changes required for maintaining the genomic integrity in all dividing cells. The process is intricate and temporally and spatially regulated by the ordered series of activation and de-activation of protein kinases. The mi
Externí odkaz:
https://doaj.org/article/ba5f4ba4ac7e4352be60509ebf8cb0c6
Autor:
Catalina M. Perelló-Reus, Teresa Rubio-Tomás, Eugenia Cisneros-Barroso, Lesly Ibargüen-González, Juan José Segura-Sampedro, Rafael Morales-Soriano, Carles Barceló
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic cancer adenocarcinoma (PDAC) is a lethal disease, with the lowest 5-years survival rate of all cancers due to late diagnosis. Despite the advance and success of precision oncology in gastrointestinal cancers, the frequency of molecular-inf
Externí odkaz:
https://doaj.org/article/fa7bac7a314c4edc860a71341638e243
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 462 (2022)
Epigenetic mechanisms are known to play a key role in cancer progression. Specifically, histone methylation involves reversible post-translational modification of histones that govern chromatin structure remodelling, genomic imprinting, gene expressi
Externí odkaz:
https://doaj.org/article/f504e329129946048cb43bafc9e2f0b1
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely related individuals is to plot allele sharing statistics, based on identity-by-state or identit
Externí odkaz:
https://doaj.org/article/1010fb8732ca431faa6996ce99352ff1
Publikováno v:
Bio-Protocol, Vol 5, Iss 6 (2015)
KRAS is the oncogene most frequently mutated in human solid tumors especially in pancreas, colon, small intestine, biliary tract and lung. We have recently demonstrated that oncogenic KRAS needs S181 phosphorylation to fully display its oncogenic fea
Externí odkaz:
https://doaj.org/article/d61cfd6e960840b09e43d3b90650388a
Autor:
Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló
PDF file - 25K, Fig. S5. GTP loading of endogenous Ras isoforms in the DLD1 KRAS wt/- cells expressing oncogenic KRAS phosphomutants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130d52bf567089089bea8ebc322fc96c
https://doi.org/10.1158/0008-5472.22401315
https://doi.org/10.1158/0008-5472.22401315
Autor:
Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló
PDF file - 51K, Fig. S1. Tumor volume of mice grafts from NIH3T3 cells expressing HA-KRAS-G12V phosphomutants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729758c6a014c3a0fec422c8a5dfd7cc
https://doi.org/10.1158/0008-5472.22401327
https://doi.org/10.1158/0008-5472.22401327
Autor:
Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló
PDF file - 646K, Fig. S3. Histological pattern of mice grafts derived from NIH3T3 expressing phosphomutants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af334184e9c5f1d2435d579eb505f4e4
https://doi.org/10.1158/0008-5472.22401321
https://doi.org/10.1158/0008-5472.22401321
Autor:
Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló
PDF file - 31K, Fig. S4. Treatment with PKC inhibitor Edelfosine inhibits tumor growth of HAKRASG12V in a Ser181 KRAS phosphorylation-dependent fashion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b806351c398f464adc2ff839887c50c1
https://doi.org/10.1158/0008-5472.22401318
https://doi.org/10.1158/0008-5472.22401318