Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Carles, Rentero"'
Autor:
Judith Cantó‐Santos, Laura Valls‐Roca, Ester Tobías, Francesc Josep García‐García, Mariona Guitart‐Mampel, Anna Esteve‐Codina, Beatriz Martín‐Mur, Mercedes Casado, Rafael Artuch, Estel Solsona‐Vilarrasa, José Carlos Fernandez‐Checa, Carmen García‐Ruiz, Carles Rentero, Carlos Enrich, Pedro J. Moreno‐Lozano, José César Milisenda, Francesc Cardellach, Josep M. Grau‐Junyent, Glòria Garrabou
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 964-977 (2023)
Abstract Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology. There is
Externí odkaz:
https://doaj.org/article/0f82886d569447a682acbe705f05bfcc
Autor:
Jaimy Jose, Monira Hoque, Johanna Engel, Syed S. Beevi, Mohamed Wahba, Mariya Ilieva Georgieva, Kendelle J. Murphy, William E. Hughes, Blake J. Cochran, Albert Lu, Francesc Tebar, Andrew J. Hoy, Paul Timpson, Kerry-Anne Rye, Carlos Enrich, Carles Rentero, Thomas Grewal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Cholesterol is considered indispensable for cell motility, but how physiological cholesterol pools enable cells to move forward remains to be clarified. The majority of cells obtain cholesterol from the uptake of Low-Density lipoproteins (LD
Externí odkaz:
https://doaj.org/article/d41d8cbae8614657a10cbd861eb353d6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Membrane contact sites (MCS) are specialized small areas of close apposition between two different organelles that have led researchers to reconsider the dogma of intercellular communication via vesicular trafficking. The latter is now being challeng
Externí odkaz:
https://doaj.org/article/674d47b588c44ca88affba5894f2280e
Autor:
Carlos Sanz-Garcia, Yulia A. Nevzorova, Eduardo Martínez-Naves, Francisco Javier Cubero, Alejandro Hionides-Gutierrez, Jose Ramón Sañudo, Carlos Enrich, Carles Rentero, Pau Sancho-Bru, Ricardo U. Macías-Rodriguez, Astrid Ruiz-Margain, David Kershenobich-Stalnikowitz, Nestor R. Vargas, Alberto E. Muñoz, Helder I. Nakaya
Publikováno v:
Gastroenterología y Hepatología (English Edition). 46:322-328
Unfortunately, there is a gap of understanding in the pathophysiology of chronic liver disease due to the lack of experimental models that exactly mimic the human disease. Additionally, the diagnosis of patients is very poor due to the lack of biomar
Autor:
Mai K. L. Nguyen, Jaimy Jose, Mohamed Wahba, Marc Bernaus-Esqué, Andrew J. Hoy, Carlos Enrich, Carles Rentero, Thomas Grewal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7206 (2022)
Cancer cells undergo drastic metabolic adaptions to cover increased bioenergetic needs, contributing to resistance to therapies. This includes a higher demand for cholesterol, which often coincides with elevated cholesterol uptake from low-density li
Externí odkaz:
https://doaj.org/article/c5b9e6d2703944838a467f538399fafe
Publikováno v:
Contact, Vol 2 (2019)
Delivery of low-density lipoprotein-derived cholesterol to the endoplasmic reticulum (ER) is essential for cholesterol homeostasis, yet the mechanism of this transport has largely remained elusive. Two recent reports shed some light on this process,
Externí odkaz:
https://doaj.org/article/22b1cc92bcfb41a380c6f5f916478031
Autor:
David Soriano-Castell, Albert Chavero, Carles Rentero, Marta Bosch, Maite Vidal-Quadras, Albert Pol, Carlos Enrich, Francesc Tebar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Clathrin-dependent and -independent pathways contribute for β1-integrin endocytosis. This study defines a tubular membrane clathrin-independent endocytic network, induced with the calmodulin inhibitor W13, for β1-integrin internalization.
Externí odkaz:
https://doaj.org/article/877bba9c2af54a73a6566a2461de34ae
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031215469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4fc627239e3e3535c3ce227867173d1
https://doi.org/10.1007/978-3-031-21547-6_15
https://doi.org/10.1007/978-3-031-21547-6_15
Autor:
Thomas Grewal, Carles Rentero, Carlos Enrich, Mohamed Wahba, Carsten A. Raabe, Ursula Rescher
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3439 (2021)
Routine manipulation of the mouse genome has become a landmark in biomedical research. Traits that are only associated with advanced developmental stages can now be investigated within a living organism, and the in vivo analysis of corresponding phen
Externí odkaz:
https://doaj.org/article/6ad1083472f24e878437917fd81fd237
Autor:
Elsa Meneses-Salas, Ana García-Melero, Patricia Blanco-Muñoz, Jaimy Jose, Marie-Sophie Brenner, Albert Lu, Francesc Tebar, Thomas Grewal, Carles Rentero, Carlos Enrich
Publikováno v:
Cells, Vol 9, Iss 5, p 1152 (2020)
We recently identified elevated annexin A6 (AnxA6) protein levels in Niemann–Pick-type C1 (NPC1) mutant cells. In these cells, AnxA6 depletion rescued the cholesterol accumulation associated with NPC1 deficiency. Here, we demonstrate that elevated
Externí odkaz:
https://doaj.org/article/a90d89b5e21644989dc53990c3e430b8