Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Carles, Gaig"'
Autor:
Amaia Muñoz-Lopetegi, Simone Baiardi, Mircea Balasa, Angela Mammana, Gerard Mayà, Marcello Rossi, Mónica Serradell, Corrado Zenesini, Alice Ticca, Joan Santamaria, Sofia Dellavalle, Carles Gaig, Alex Iranzo, Piero Parchi
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract We investigated the biomarker profile of neurodegeneration, Alzheimer’s and Lewy body pathology in the CSF of 148 polysomnography-confirmed patients with isolated REM sleep behavior disorder (IRBD), a condition that precedes Parkinson’s
Externí odkaz:
https://doaj.org/article/3c0ceb9607fd4beba2c1ec141a17292b
Autor:
Inga Koneczny, Stefan Macher, Markus Hutterer, Thomas Seifert-Held, Evelyn Berger-Sieczkowski, Morten Blaabjerg, Markus Breu, Jens Dreyhaupt, Livia Almeida Dutra, Marcus Erdler, Ingrid Fae, Gottfried Fischer, Florian Frommlet, Anna Heidbreder, Birgit Högl, Veronika Klose, Sigrid Klotz, Herburg Liendl, Mette S. Nissen, Jasmin Rahimi, Raphael Reinecke, Gerda Ricken, Ambra Stefani, Marie Süße, Helio A. G. Teive, Serge Weis, Thomas Berger, Lidia Sabater, Carles Gaig, Jan Lewerenz, Romana Höftberger
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAnti-IgLON5 disease is a rare chronic autoimmune disorder characterized by IgLON5 autoantibodies predominantly of the IgG4 subclass. Distinct pathogenic effects were described for anti-IgLON5 IgG1 and IgG4, however, with uncertain clinical
Externí odkaz:
https://doaj.org/article/4973fe045006435cbdd85643ef22108a
Autor:
Margalida Puigròs, Anna Calderon, Daniel Martín-Ruiz, Mònica Serradell, Manel Fernández, Amaia Muñoz-Lopetegi, Gerard Mayà, Joan Santamaria, Carles Gaig, Anna Colell, Eduard Tolosa, Alex Iranzo, Ramon Trullas
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105065- (2024)
Summary: Background: Idiopathic rapid eye movement (REM) sleep behaviour disorder (IRBD) represents the prodromal stage of Lewy body disorders (Parkinson's disease (PD) and dementia with Lewy bodies (DLB)) which are linked to variations in circulatin
Externí odkaz:
https://doaj.org/article/ffffee7d37fc4a8c8da4cca684795f85
Autor:
Jon Landa, Ana Beatriz Serafim, Carles Gaig, Albert Saiz, Inga Koneczny, Romana Hoftberger, Joan Santamaria, Josep Dalmau, Francesc Graus, Lidia Sabater
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/daddfd7062254d899bfa4399989e1fb0
Autor:
Jon Landa, Ana Beatriz Serafim, Carles Gaig, Albert Saiz, Inga Koneczny, Romana Hoftberger, Joan Santamaria, Josep Dalmau, Francesc Graus, Lidia Sabater
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAnti-IgLON5 disease is a rare neurological disorder characterized by autoantibodies against IgLON5, and pathological evidence of neurodegeneration. IgLON5 is a cell adhesion molecule but its physiological function is unknown. Our aim was to
Externí odkaz:
https://doaj.org/article/0b92697c34fa474aa6fdc1a91b8b2a22
Autor:
Ariadna Laguna, Helena Xicoy, Eduardo Tolosa, Mònica Serradell, Dolores Vilas, Carles Gaig, Manel Fernández, Oscar Yanes, Joan Santamaria, Núria Amigó, Alex Iranzo, Miquel Vila
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal stage of Lewy-type synucleinopathies (LTS), which can present either with an initial predominant parkinsonism (Parkinson’s disease (PD)) or dementia (dementia
Externí odkaz:
https://doaj.org/article/bec3a6f30fef41dabe057654c4d8d8bc
Autor:
Jordi Sarto, Berta Caballol, Joan Berenguer, Iban Aldecoa, Álvaro Carbayo, Daniel Santana, Ivan Archilla, Carles Gaig, Francesc Graus, Julián Panés, Albert Saiz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 15 (2022)
Ustekinumab, a monoclonal antibody against interleukin (IL)-12 and IL-23 approved for the treatment of Crohn’s disease, has shown to be an effective therapy with a favourable safety profile. Clinical trials and real-world studies have reported very
Externí odkaz:
https://doaj.org/article/a10147c4113145eb9dbe8d4be37e0a00
Autor:
Alejandra Collía, Alex Iranzo, Mónica Serradell, Amaia Muñoz-Lopetegi, Gerard Mayà, Joan Santamaría, Raquel Sánchez-Valle, Carles Gaig
Publikováno v:
Journal of Neurology. 270:3234-3242
Autor:
Alex Iranzo, Angela Mammana, Amaia Muñoz-Lopetegi, Sofia Dellavalle, Gerard Mayà, Marcello Rossi, Monica Serradell, Simone Baiardi, Aurora Arqueros, Corinne Quadalti, Andres Perissinotti, Edoardo Ruggeri, Joan Santamaria Cano, Carles Gaig, Piero Parchi
Publikováno v:
Neurology. 100:e1944-e1954
Background and ObjectivesReal-time quaking-induced conversion (RT-QuIC) assay detects misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies Parkinson disease and dementia with Lewy bodies. Isolated REM sleep behavior
Autor:
Morten Gersel Stokholm, Alex Iranzo, Karen Østergaard, Mónica Serradell, Marit Otto, Kristina Bacher Svendsen, Alicia Garrido, Dolores Vilas, Peter Parbo, Per Borghammer, Joan Santamaria, Arne Møller, Carles Gaig, David J. Brooks, Eduardo Tolosa, Nicola Pavese
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 9-16 (2018)
Background: The majority of patients diagnosed with idiopathic rapid eye movement sleep behaviour disorder (iRBD) progress over time to a Lewy-type α-synucleinopathy such as Parkinson's disease or dementia with Lewy bodies. This in vivo molecular im
Externí odkaz:
https://doaj.org/article/fe8be94c085543cf8701d69a6a62cecd