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pro vyhledávání: '"Carleen Klummp-Thomas"'
Autor:
Juan Juan Yin, Michael L. Beshiri, John B. Tucker, R. Mark Simpson, Carleen Klummp-Thomas, Holly M. Nguyen, Caitlin M. Tice, Shelley E Hoover, Lei Fang, Supreet Agarwal, Paul G. Hynes, Ross Lake, Caitlyn Fuller, Eva Corey, Rajarshi Guha, Yasmine C. Abbey, Craig J. Thomas, Keith H. Jansson, Jacob Cawley, Aian Neil Alilin, John K. Simmons, Xiaohu Zhang, Lauren E. Stahl, David A. Proia, Crystal McKnight, Kathleen Kelly
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
The development of new treatments for castrate resistant prostate cancer (CRPC) must address such challenges as intrinsic tumor heterogeneity and phenotypic plasticity. Combined PTEN/TP53 alterations represent a major genotype of CRPC (25–30%) and