Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carleen K. Everett"'
Publikováno v:
Cancer Letters. 111:133-139
The growth inhibitory properties of alpha-tocopheryl hemisuccinate (vitamin E succinate) and related compounds were examined in MCF-7 human breast tumor cells and MCF-10A normal-like human breast cells since they have been suggested to be an effectiv
Autor:
Thomas H. Corbett, Carleen K. Everett, Frederick A. Valeriote, Jeffrey L. Evelhoch, Wilfried De Neve, Nicholas E. Simpson, Marie Christine Bissery
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 18:1359-1365
Flavone acetic acid (FAA) is a new anticancer agent in Phase II trials in Europe. In preclinical testing FAA showed broad activity against murine solid tumors and minimal activity against murine leukemias. Our interest in studying the combination of
Autor:
Carleen K. Everett, Efstathios Tapazoglou, Thomas H. Corbett, Anup K Khatana, Wilfried DeNeve, Frederick A. Valeriote
Publikováno v:
Investigational New Drugs. 8:17-24
We used the method of alkaline elution to compare quantitatively the DNA lesions produced by cisplatin and carboplatin in the AKR leukemia in vivo. These data were compared with cytotoxicity of each drug in the same animal model and in a solid tumor
Publikováno v:
Free radical biologymedicine. 24(2)
Flow cytometric analysis of nucleoids is useful to investigate nuclear matrix-DNA associations in cells. We have now applied this technique to examine whether differences in nucleoid structure can be detected between tumor and normal-like human breas
Publikováno v:
Free radical biologymedicine. 14(5)
DNA damage induced by oxidants includes formation of DNA strand breaks as well as oxidative damage to DNA bases. We quantified both forms of DNA damage concurrently in two model human breast epithelial cell lines treated with hydrogen peroxide to com