Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carla Y. Pumphrey"'
Autor:
Wayne A. Marasco, Carla Y. Pumphrey
Publikováno v:
BioDrugs. 9:179-185
Antibody engineering techniques permit the exploitation of the highly specific and diverse nature of the humoral immune system. Intracellular antibodies, consisting minimally of the antigen-binding domains of the parent immunoglobulin protein, may be
Autor:
Wayne L. Gray, Carla Y. Pumphrey
Publikováno v:
Journal of General Virology. 75:3219-3227
The varicella-zoster virus (VZV) glycoprotein B (gB) is a major viral antigen which elicits immunity and neutralizing antibodies. In this study, the genomic map position and DNA sequence of a simian varicella virus (SVV) homologue of the VZV gB gene
Publikováno v:
Virology. 186:562-572
Simian varicella virus (SVV) DNA was purified from viral nucleocapsids and the molecular structure of the SVV genome was determined. SVV DNA was analyzed by agarose gel electrophoresis of BamHI, BglII, EcoRI, and PstI restriction endonuclease digests
Publikováno v:
Cancer research. 62(13)
The soluble form of the syndecan-1 heparan sulfate proteoglycan acts as a tumor suppressor molecule that inhibits growth and induces apoptosis of some cancer cell lines in vitro. Analogs of syndecan-1 were produced by carbodiimide (EDAC) conjugation
Autor:
Allison Theus, Joshua Epstein, J. Kevin Langford, Wei Liu, Shmuel Yaccoby, Yang Yang, Ralph D. Sanderson, Carla Y. Pumphrey
Publikováno v:
Blood. 100(2)
Syndecan-1 (CD138) is a transmembrane heparan sulfate–bearing proteoglycan expressed by most myeloma plasma cells that regulates adhesion, migration, and growth factor activity. In patients with myeloma, shed syndecan-1 accumulates in the bone marr
Autor:
Saskia Boisot, Jeffrey H. Dove, Joyce Lavecchio, Carla Y. Pumphrey, Richard N. Weissmahr, Abner M. Mhashilkar, David Ring, Urban Ramstedt, Wayne A. Marasco, Xuguang Li, Bridget Eberhardt, Julie Porter-Brooks
Publikováno v:
Human gene therapy. 10(9)
We have previously reported that a murine anti-Tat sFv intrabody, termed sFvtat1Ck, directed against the proline-rich N-terminal activation domain of HIV-1, is a potent inhibitor of HIV-1 replication [Mhashilkar, A. M., et al. (1995). EMBO J. 14, 154
Autor:
Carla Y. Pumphrey, Wayne L. Gray
Publikováno v:
Virus research. 38(1)
The varicella zoster virus (VZV) glycoprotein H (gH) stimulates VZV-specific immune responses and may be involved in virus penetration. This study reports the genomic map position and the DNA sequence of a simian varicella virus (SVV) homologue of th
Publikováno v:
The Journal of general virology. 74
The size and genomic location of viral transcripts expressed in simian varicella virus (SVV)-infected Vero cells were determined. Total cellular RNA and polyadenylated RNA were isolated from SVV-infected and mock-infected Vero cells. Viral transcript
Autor:
Carla Y. Pumphrey, Wayne L. Gray
Publikováno v:
Virus research. 26(3)
Simian varicella virus (SVV) causes an exanthematous disease in non-human primates which is clinically similar to varicella zoster virus (VZV) infection of humans. In this study, the genetic relatedness of SVV and VZV was confirmed and the location o