Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carla Umansky"'
Autor:
Carla Umansky, Agustín E. Morellato, Matthias Rieckher, Marco A. Scheidegger, Manuela R. Martinefski, Gabriela A. Fernández, Oleg Pak, Ksenia Kolesnikova, Hernán Reingruber, Mariela Bollini, Gerry P. Crossan, Natascha Sommer, María Eugenia Monge, Björn Schumacher, Lucas B. Pontel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Formaldehyde (FA) is known to exert cytotoxicity through DNA damage. Here, the authors show that FA also triggers cellular redox imbalance by reacting with glutathione (GSH), and that FA cytotoxicity is prevented by GSH synthesis and by ADH5, an enzy
Externí odkaz:
https://doaj.org/article/653aae910d4d4b0192f151bf36477da9
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
Writing in Nature communications, Zhu and collaborators reported the development of a genetically encoded sensor for the detection of formaldehyde in cells and tissues. This tool has great potential to transform formaldehyde research; illuminating a
Externí odkaz:
https://doaj.org/article/5de92fa968884150b00586326a7c9df2
Publikováno v:
Redox Biology, Vol 40, Iss , Pp 101850- (2021)
One-carbon metabolism is a central metabolic hub that provides one-carbon units for essential biosynthetic reactions and for writing epigenetics marks. The leading role in this hub is performed by the one-carbon carrier tetrahydrofolate (THF), which
Externí odkaz:
https://doaj.org/article/95672038f5a54da585defa3bddc563e2
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
Nature Communications
Nature Communications
Formaldehyde (FA) has long been considered as a toxin and carcinogen due to its damaging effects to biological macromolecules, but its beneficial roles have been increasingly appreciated lately. Real-time monitoring of this reactive molecule in livin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0053226e8e47cc40a73eff05940340
https://doaj.org/article/5de92fa968884150b00586326a7c9df2
https://doaj.org/article/5de92fa968884150b00586326a7c9df2
Publikováno v:
Redox Biology, Vol 40, Iss, Pp 101850-(2021)
Redox Biology
Redox Biology
One-carbon metabolism is a central metabolic hub that provides one-carbon units for essential biosynthetic reactions and for writing epigenetics marks. The leading role in this hub is performed by the one-carbon carrier tetrahydrofolate (THF), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef752ee6140eef606b6736d6e97368dd
http://www.sciencedirect.com/science/article/pii/S2213231720310557
http://www.sciencedirect.com/science/article/pii/S2213231720310557
Autor:
Gabriela Araceli Fernandez, Yan Wei, Manuela Romina Martinefski, Bj oumlrn Schumacher, Lucas B. Pontel, Mariela Bollini, Matthias Rieckher, Ismene Karakasilioti, Ksenia Kolesnikova, Carla Umansky, Agust iacuten Morellato, Rongqiao He, Hern aacuten Reingruber, Anna Juliane Vesting, Marco Scheidegger, Mar iacutea Eugenia Monge
Formaldehyde (FA) is a ubiquitous endogenous and environmental metabolite that is thought to exert cytotoxicity through DNA and DNA-protein crosslinking. We show here that FA can cause cellular damage beyond genotoxicity by triggering oxidative stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceecfff427a46708bce9587a4b393ec7
https://doi.org/10.1101/2020.05.14.090738
https://doi.org/10.1101/2020.05.14.090738
