Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carla S, Capobianco"'
Autor:
Luisina M. Solernó, Natasha T. Sobol, María F. Gottardo, Carla S. Capobianco, Maximiliano R. Ferrero, Liliana Vásquez, Daniel F. Alonso, Juan Garona
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Osteosarcoma is still associated with limited response to standard-of-care therapy and alarmingly elevated mortality rates, especially in low- and middle-income countries. Despite multiple efforts to repurpose β-blocker propranolol in oncol
Externí odkaz:
https://doaj.org/article/76e6670f3c4042928bf7821dcad04983
Autor:
Johanna E. Sidabra, Silvio E. Perea, Hernan G. Farina, Carla S. Capobianco, Maria F. Gottardo, Yasser Perera, Daniel F. Alonso, Juan Garona
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
CK2 is a serine/threonine kinase that is overexpressed in breast cancer and its inhibition is associated to reduced tumor growth and disease progression. CIGB-300 is an antitumor peptide with a novel mechanism of action, since it binds to protein kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f09870c4c8063f385bfc8ae26ae80e
http://link.springer.com/article/10.1038/s41598-020-71854-6
http://link.springer.com/article/10.1038/s41598-020-71854-6
Autor:
Luisina M, Solernó, Natasha T, Sobol, María F, Gottardo, Carla S, Capobianco, Maximiliano R, Ferrero, Liliana, Vásquez, Daniel F, Alonso, Juan, Garona
Publikováno v:
Scientific reports. 12(1)
Osteosarcoma is still associated with limited response to standard-of-care therapy and alarmingly elevated mortality rates, especially in low- and middle-income countries. Despite multiple efforts to repurpose β-blocker propranolol in oncology, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::460571a05e95643173577b2b456f9f01
https://pubmed.ncbi.nlm.nih.gov/36075937
https://pubmed.ncbi.nlm.nih.gov/36075937
Autor:
Liliana Vasquez, Carla S. Capobianco, Luisina M. Solernó, Giselle V. Ripoll, Juan Garona, Daniel Fernando Alonso, Natasha Tatiana Sobol
Background: Osteosarcoma is still associated with poor response to therapy and alarmingly elevated mortality rates, especially in developing countries, highlighting the urgent need of novel therapeutic strategies. Given that β-adrenergic receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75cbaaab23248d5435ce8695a5f62f8c
https://doi.org/10.21203/rs.3.rs-44912/v1
https://doi.org/10.21203/rs.3.rs-44912/v1
Autor:
Gretel M. Ferreira, Mariano R. Gabri, Selene Rojo, Valeria Inés Segatori, Héctor Adrián Cuello, Daniel A. Alonso, Cynthia A. Gulino, Carla S. Capobianco
Publikováno v:
Cancer Research. 80:6648-6648
N-glycolylneuraminic acid (NeuGc) is a sialic acid molecule present in mammalian cells as terminal constituents of membrane glycoconjugates such as gangliosides and glycoproteins. Although the role of NeuGc-containing glycoconjugates in human cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c7e44e2958749b657896cf54214072
https://doi.org/10.1158/1538-7445.am2020-6648
https://doi.org/10.1158/1538-7445.am2020-6648
Autor:
Hernan G. Farina, Carla S. Capobianco, María Florencia Gottardo, Daniel F. Alonso, Johanna E. Sidabra
Publikováno v:
Cancer Research. 80:2649-2649
Breast cancer is the first cause of death from female cancer. After treatments against the primary tumor, a few cells can prevail in a dormant state for a long period, becoming minimal residual disease. These cells can resume growth and establish as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b460ef668009c70bd83690e33ef9fa14
https://doi.org/10.1158/1538-7445.am2020-2649
https://doi.org/10.1158/1538-7445.am2020-2649
Autor:
Johanna E. Sidabra, Carla S. Capobianco, Maria F. Gottardo, Juan Garona, Daniel F. Aonso, Silvio Perea Rodriguez, Hernan G. Farina
Publikováno v:
Cancer Research. 80:6232-6232
CK2 is a serine/threonine kinase that is overexpressed in breast cancer and its inhibition is associated to reduced tumor growth and disease progression. With more than three hundred substrates, this kinase is involved in a large number of cellular f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98b085556f96af1f35790c72042a12c
https://doi.org/10.1158/1538-7445.am2020-6232
https://doi.org/10.1158/1538-7445.am2020-6232
Autor:
Hernan G. Farina, Johanna E. Sidabra, Carla S. Capobianco, Maria F. Gottardo, Julio A. Aguirre Ghiso, Daniel F. Alonso
Publikováno v:
Cancer Research. 80:5983-5983
The p38 pathway can be activated by three different MAP kinase kinases: MKK3, MKK4 and MKK6, each one activated by different stimuli, like DNA damage, oxidative stress, proinflammatory cytokines or growth factors. In consequence, the responses mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50498b839f0d3e773b6cb8060baeca3
https://doi.org/10.1158/1538-7445.am2020-5983
https://doi.org/10.1158/1538-7445.am2020-5983
Autor:
Juan Garona, Hernan G. Farina, Silvio E. Perea, Fernando Rodrigo Benavent Acero, Carla S. Capobianco, Alejandro J. Urtreger, Daniel F. Alonso, Stefano M. Cirigliano, Yasser Perera
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Objectives: Casein kinase 2 (CK2) is overexpressed in several types of cancer. It has more than 300 substrates mainly involved in DNA reparation and replication, chromatin remodeling and cellular growth. In recent years CK2 became an interesting targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ca828f75f2b68a8eca1d4185613181
https://www.sciencedirect.com/science/article/pii/S016950021630352X
https://www.sciencedirect.com/science/article/pii/S016950021630352X
Autor:
Carla S. Capobianco, Daniel F. Alonso, Johanna E. Sidabra, Julio A. Aguirre-Ghiso, Maria F. Gottardo, Hernan G. Farina
Publikováno v:
Cancer Research. 78:78-78
The mitogen activated protein kinase (MAPK) p38 is a kinase involved in the response to different external stimuli, extremely diverse such as oxidative stress or growth factors. Its activation triggers different responses which include from promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c5bc083c57ebcac584a8d044cb708a6
https://doi.org/10.1158/1538-7445.am2018-78
https://doi.org/10.1158/1538-7445.am2018-78