Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carla Roots"'
Autor:
Zahra Sabouri, Samuel Perotti, Emily Spierings, Peter Humburg, Mehmet Yabas, Hannes Bergmann, Keisuke Horikawa, Carla Roots, Samantha Lambe, Clara Young, T. Dan Andrews, Matthew Field, Anselm Enders, Joanne H. Reed, Christopher C. Goodnow
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Self-reactive B cells that are anergic express mainly IgD, yet the function of IgD is not clear. Here the authors analyse primary B cells from mice to show that IgD signalling attenuates self-antigen induced gene expression and promotes survival of a
Externí odkaz:
https://doaj.org/article/33bf5d14b2104b7e9e5694830f9f9ee0
Autor:
Stephen R Daley, Kristen M Coakley, Daniel Y Hu, Katrina L Randall, Craig N Jenne, Andre Limnander, Darienne R Myers, Noelle K Polakos, Anselm Enders, Carla Roots, Bhavani Balakishnan, Lisa A Miosge, Geoff Sjollema, Edward M Bertram, Matthew A Field, Yunli Shao, T Daniel Andrews, Belinda Whittle, S Whitney Barnes, John R Walker, Jason G Cyster, Christopher C Goodnow, Jeroen P Roose
Publikováno v:
eLife, Vol 2 (2013)
Missense variants are a major source of human genetic variation. Here we analyze a new mouse missense variant, Rasgrp1Anaef, with an ENU-mutated EF hand in the Rasgrp1 Ras guanine nucleotide exchange factor. Rasgrp1Anaef mice exhibit anti-nuclear aut
Externí odkaz:
https://doaj.org/article/99a34eaaa5914ca98a046571e4a1f72a
Autor:
Nathan W, Zammit, Owen M, Siggs, Paul E, Gray, Keisuke, Horikawa, David B, Langley, Stacey N, Walters, Stephen R, Daley, Claudia, Loetsch, Joanna, Warren, Jin Yan, Yap, Daniele, Cultrone, Amanda, Russell, Elisabeth K, Malle, Jeanette E, Villanueva, Mark J, Cowley, Velimir, Gayevskiy, Marcel E, Dinger, Robert, Brink, David, Zahra, Geeta, Chaudhri, Gunasegaran, Karupiah, Belinda, Whittle, Carla, Roots, Edward, Bertram, Michiko, Yamada, Yogesh, Jeelall, Anselm, Enders, Benjamin E, Clifton, Peter D, Mabbitt, Colin J, Jackson, Susan R, Watson, Craig N, Jenne, Lewis L, Lanier, Tim, Wiltshire, Matthew H, Spitzer, Garry P, Nolan, Frank, Schmitz, Alan, Aderem, Benjamin T, Porebski, Ashley M, Buckle, Derek W, Abbott, John B, Ziegler, Maria E, Craig, Paul, Benitez-Aguirre, Juliana, Teo, Stuart G, Tangye, Cecile, King, Melanie, Wong, Murray P, Cox, Wilson, Phung, Jia, Tang, Wendy, Sandoval, Ingrid E, Wertz, Daniel, Christ, Christopher C, Goodnow, Shane T, Grey
Publikováno v:
Nature immunology. 20(10)
Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms controlling this balance. Here genomic analyses of anatomically modern humans, extinct Denisovan hominins and mic