Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carla Rodriguez Mogeda"'
Autor:
Carla Rodriguez-Mogeda, Melissa MJ van Gool, Richard van der Mast, Rutger Nijland, Zoë Keasberry, Lisanne van de Bovekamp, Myrthe AM van Delft, Carmen Picon, Richard Reynolds, Joep Killestein, Charlotte E Teunissen, Helga E de Vries, Marjolein van Egmond, Maarten E Witte
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Intrathecal synthesis of immunoglobulins (Igs) is a key hallmark of multiple sclerosis (MS). B cells are known to accumulate in the leptomeninges of MS patients and associate with pathology in the underlying cortex and a more severe disease
Externí odkaz:
https://doaj.org/article/d0785083e3a8472d80607cfbb25ef070
Autor:
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodriguez, Inge M. W. Verberk, Sanne G. S. Verberk, Danielle W. R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff, Dorine Wouters, Jan Van den Bossche, Juan J. Garcia-Vallejo, Afina W. Lemstra, Maarten E. Witte, Wiesje M. van der Flier, Charlotte E. Teunissen, Helga E. de Vries
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Alzheimer’s disease (AD) is the most frequent cause of dementia. Recent evidence suggests the involvement of peripheral immune cells in the disease, but the underlying mechanisms remain unclear. Methods We comprehensively mapped
Externí odkaz:
https://doaj.org/article/bbeaac8f21914591a0b29202e34aed6d
Inflammation-induced TRPV4 channels exacerbate blood–brain barrier dysfunction in multiple sclerosis
Autor:
Cathrin E. Hansen, Alwin Kamermans, Kevin Mol, Kristina Berve, Carla Rodriguez-Mogeda, Wing Ka Fung, Bert van het Hof, Ruud D. Fontijn, Susanne M. A. van der Pol, Laura Michalick, Wolfgang M. Kuebler, Boyd Kenkhuis, Willeke van Roon-Mom, Wolfgang Liedtke, Britta Engelhardt, Gijs Kooij, Maarten E. Witte, Helga E. de Vries
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Blood–brain barrier (BBB) dysfunction and immune cell migration into the central nervous system (CNS) are pathogenic drivers of multiple sclerosis (MS). Ways to reinstate BBB function and subsequently limit neuroinflammation pre
Externí odkaz:
https://doaj.org/article/20142c75d08c47bfb64eb7ea8bb2e9c3
Autor:
Carla Rodriguez-Mogeda, Chaja M. J. van Ansenwoude, Lennart van der Molen, Eva M. M. Strijbis, Reina E. Mebius, Helga E. de Vries
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Emerging evidence suggests a potential role for natural killer (NK) cells in neurodegenerative diseases, such as multiple sclerosis, Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. However, the precise functio
Externí odkaz:
https://doaj.org/article/b6d11106cbef4106b204fb6008bd1836
Autor:
Carla Rodriguez-Mogeda, Zoë Y. G. J. van Lierop, Susanne M. A. van der Pol, Loet Coenen, Laura Hogenboom, Alwin Kamermans, Ernesto Rodriguez, Jack van Horssen, Zoé L. E. van Kempen, Bernard M. J. Uitdehaag, Charlotte E. Teunissen, Maarten E. Witte, Joep Killestein, Helga E. de Vries
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Recent studies suggest that extended interval dosing of ocrelizumab, an anti-B cell therapy, does not affect its clinical effectiveness in most patients with multiple sclerosis (MS). However, it remains to be established whether c
Externí odkaz:
https://doaj.org/article/3f86be80f38742afbf3232690c390a1c
Autor:
Sabela Rodríguez-Lorenzo, Lynn van Olst, Carla Rodriguez-Mogeda, Alwin Kamermans, Susanne MA van der Pol, Ernesto Rodríguez, Gijs Kooij, Helga E de Vries
Publikováno v:
eLife, Vol 11 (2022)
Multiple sclerosis (MS) is a chronic demyelinating disease characterised by immune cell infiltration resulting in lesions that preferentially affect periventricular areas of the brain. Despite research efforts to define the role of various immune cel
Externí odkaz:
https://doaj.org/article/8f80dc2ed6184bb283824a31174bab7e
Autor:
Carla Rodriguez-Mogeda, Sabela Rodríguez-Lorenzo, Jiji Attia, Jack van Horssen, Maarten E. Witte, Helga E. de Vries
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 800 (2022)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) known for the manifestation of demyelinated lesions throughout the CNS, leading to neurodegeneration. To date, not all pathological mechanisms that drive disease p
Externí odkaz:
https://doaj.org/article/de593a967d3c4ae8aba5e13fc7eabf8f
Autor:
Doryssa Hermans, Carla Rodriguez-Mogeda, Hannelore Kemps, Annelies Bronckaers, Helga E. de Vries, Bieke Broux
Publikováno v:
Angiogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41055babb0dd9c33edf6f8789ccd9333
https://doi.org/10.1007/s10456-023-09879-4
https://doi.org/10.1007/s10456-023-09879-4
Autor:
Doryssa Hermans, Carla Rodriguez-Mogeda, Hannelore Kemps, Annelies Bronckaers, Helga E. de Vries, Bieke Broux
Publikováno v:
Hermans, D, Rodriguez-Mogeda, C, Kemps, H, Bronckaers, A, de Vries Helga, E & Broux, B 2023, ' Nectins and Nectin-like molecules drive vascular development and barrier function ', Angiogenesis, vol. 26, no. 3, pp. 349-362 . https://doi.org/10.1007/s10456-023-09871-y
Angiogenesis, barriergenesis, and immune cell migration are all key physiological events that are dependent on the functional characteristics of the vascular endothelium. The protein family of Nectins and Nectin-like molecules (Necls) is a group of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d764bad5aa6fd73d505c58c2e789594
https://doi.org/10.1007/s10456-023-09871-y
https://doi.org/10.1007/s10456-023-09871-y
Autor:
Carla Rodriguez-Mogeda, Sabela Rodríguez-Lorenzo, Jiji Attia, Jack van Horssen, Maarten E. Witte, Helga E. de Vries
Publikováno v:
Rodriguez-Mogeda, C, Rodríguez-Lorenzo, S, Attia, J, van Horssen, J, Witte, M E & de Vries, H E 2022, ' Breaching Brain Barriers : B Cell Migration in Multiple Sclerosis ', Biomolecules, vol. 12, no. 6, 800 . https://doi.org/10.3390/biom12060800, https://doi.org/10.3390/biom12060800
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) known for the manifestation of demyelinated lesions throughout the CNS, leading to neurodegeneration. To date, not all pathological mechanisms that drive disease p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6cc0fa222899e1590b437346dc6f4f
https://research.vumc.nl/en/publications/c846483d-a96b-450c-9294-abcf5004080a
https://research.vumc.nl/en/publications/c846483d-a96b-450c-9294-abcf5004080a
