An Aedes aegypti seryl-tRNA synthetase paralog controls bacteroidetes growth in the midgut

Autor: Gilbert de O. Silveira, Octávio A. C. Talyuli, Ana Beatriz Walter-Nuno, Ana Crnković, Ana C. P. Gandara, Alessandro Gaviraghi, Vanessa Bottino-Rojas, Dieter Söll, Carla Polycarpo

Insect gut microbiota plays important roles in host physiology, such as nutrition, digestion, development, fertility, and immunity. We have found that in the intestine of Aedes aegypti, SLIMP (seryl-tRNA synthetase like insect mitochondrial protein)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f87baa3b2e294b173cd77893b76fba5c
https://doi.org/10.1101/2022.08.25.505225

The essential function of the Trypanosoma brucei Trl1 homolog in procyclic cells is maturation of the intron-containing tRNATyr

Autor: Alan C. Kessler, Carla Polycarpo, Juan D. Alfonzo, Raphael R.S. Lopes, Gilbert de O. Silveira, Scott Hinger, Roberta Eitler, Raphael Silveira Vidal, Zdeněk Paris

Publikováno v: RNA. 22:1190-1199

Trypanosoma brucei, the etiologic agent of sleeping sickness, encodes a single intron-containing tRNA, tRNATyr, and splicing is essential for its viability. In Archaea and Eukarya, tRNA splicing requires a series of enzymatic steps that begin with in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245f84338556f007a305ad847eba82cd
https://doi.org/10.1261/rna.056242.116

Recognition of pyrrolysine tRNA by the Desulfitobacterium hafniense pyrrolysyl-tRNA synthetase

Autor: Carla Polycarpo, Dieter Söll, Stephanie Herring, Alexandre Ambrogelly

Publikováno v: Nucleic Acids Research

Pyrrolysine (Pyl), the 22nd co-translationally inserted amino acid, is incorporated in response to a UAG amber stop codon. Pyrrolysyl-tRNA synthetase (PylRS) attaches Pyl to its cognate tRNA, the special amber suppressor tRNA(Pyl). The genes for tRNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f39424cf8f0e92f1a9ff98c14a098db
http://europepmc.org/articles/PMC1851642

Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection

Autor: Carla Polycarpo, Magda D. Lugon, Emmanuelle Jacquin-Joly, Francisco Prosdocimi, Katia C. Gondim, Daniel Lawson, Raquel J. Vionette-Amaral, Karyn Megy, Andrew Pike, Fernando A. Monteiro, David Majerowicz, Marco Mariotti, Gloria I. Giraldo-Calderón, Fernando G. Noriega, Ana Beatriz Walter-Nuno, M. Patricia Juárez, Leonardo Koerich, A. Bernardo Carvalho, Marcos Sterkel, Fernando Abad-Franch, Catrina Fronick, Samara G. da Costa, Eloy S. Seabra-Junior, Márcio G. Pavan, Pedro L. Oliveira, Willy Jablonka, Myriam Harry, Ana C.A. Melo, Rita D. Fernandez-Medina, George Dimopoulos, Igor Rodrigues da Costa, Cristiano Lazoski, Alessandra A. Guarneri, Paula L. Marcet, Lucinda Fulton, Gena G. Lawrence, Patrícia Azambuja, Gabriela O. Paiva-Silva, Adriana Granzotto, Francisco Panzera, Marcelo G. Lorenzo, Didac Santesmasses, Raquel L.L. Oliveira, Ricardo Nascimento Araújo, Hugh M. Robertson, Renata Schama, Matheus Souza-Gomes, Didier Salmon, Iron F. De-Paula, José M. C. Ribeiro, Roderic Guigó, Derek Wilson, Ana Caroline P. Gandara, Rolando Rivera-Pomar, André Q. Torres, Raul Ursic-Bedoya, Andrés Lavore, Scott J. Emrich, Marcio Fontenele, Laurence Rodrigues do Amaral, Felipe A. Dias, Mário A.C. Silva-Neto, Claudia M. A. Carareto, John Spieth, Nicolás Pedrini, Erwin Huebner, Claudio R. Lazzari, Rafael D. Mesquita, Helena Araujo, Ian Orchard, Fernando A. Genta, Daniel S.T. Hughes, Zhijian Jake Tu, Carl Lowenberger, Paula R. Bittencourt-Cunha, Marcos Henrique Ferreira Sorgine, Michael J. Montague, Rodrigo Nunes da Fonseca, Gustavo M. Calderón-Fernández, Alexandre A. Peixoto, Marcela Nouzova, Angela B. Lange, Gilbert Oliveira-Silveira, Eloi S. Garcia, L. Aravind, Ellen M. Dotson, Hatisaburo Masuda, Glória R.C. Braz, Bruno Gomes, Natalia Esponda-Behrens, Raphael R.S. Lopes, Marilvia Dansa, Sheila Ons, Patrícia Fampa, Rodrigo Dutra Nunes, Mikkel B. Christensen, Ana Paula Salerno, Mabel L. Taracena, Marta Tojo, Georgia C. Atella, Jose Manuel Latorre-Estivalis, Marcos H. Pereira, Agustina Pascual, Michele Alves-Bezerra, Robert M. Waterhouse, Theo Mota, Rodrigo Ribeiro-Rodrigues, Thiago M. Venancio, Lucia Pagola, Fanis Missirlis, Carlos R. O. Daumas-Filho, Jose M. C. Tubio, Lívia Silva-Cardoso, Wesley C. Warren, Richard K. Wilson, Patrick Minx, Mateus Berni

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 48 (112), 14936-14941. (2015)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (48), pp.14936-14941. ⟨10.1073/pnas.1506226112⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Proceedings of the National Academy of Sciences, Vol. 112, No 48 (2015) pp. 14936-14941
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d307d1cca8b34fea1fc7b2801389221
http://prodinra.inra.fr/record/343628

Cutting, dicing, healing and sealing: the molecular surgery of tRNA

Autor: Raphael R S, Lopes, Alan C, Kessler, Carla, Polycarpo, Juan D, Alfonzo

Publikováno v: Wiley interdisciplinary reviews. RNA. 6(3)

All organisms encode transfer RNAs (tRNAs) that are synthesized as precursor molecules bearing extra sequences at their 5′ and 3′ ends; some tRNAs also contain introns, which are removed by splicing. Despite commonality in what the ultimate goal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e6ef2302496df302d8c6e44f91ce401
https://pubmed.ncbi.nlm.nih.gov/25755220