Network integration and modelling of dynamic drug responses at multi-omics levels

Autor: Witold Wolski, Irina Agarkova, Hans Gmuender, Stefano Gotta, Ugis Sarkans, Ralf Herwig, Adrian Roth, Johannes Schuchhardt, Henrik Cordes, Patrick Guye, Bernd Timmermann, Steven A. Niederer, Jos C. S. Kleinjans, Marcha Verheijen, Jasmine Minguet, Sally J. Deeb, Carla Pluess, Vanessa Baier, Matthias Lienhard, Ivo Bachmann, Jort J. Merken, Alexandra Zerck, Stefan Boerno, Ramona Nudischer, Anne Hersey, Christoph Thiel, Francis Atkinson, Olivia Clayton, Laura Kunz, Lars Kuepfer, Fiona M. I. Hunter, Christopher F. Bauer, Stephane Heymans, Yannick Schrooders, Gal Barel, Nathalie Selevsek, Alex Lewalle, Ralph Schlapbach, Nicolas Bosc, Florian Caiment, Timo Wittenberger, Ines Smit, Bernardo Lino de Oliveira

Publikováno v: Communications Biology
Communications Biology, 3(1):573. Nature Publishing Group
Communications biology 3, 573 (2020). doi:10.1038/s42003-020-01302-8
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)

Uncovering cellular responses from heterogeneous genomic data is crucial for molecular medicine in particular for drug safety. This can be realized by integrating the molecular activities in networks of interacting proteins. As proof-of-concept we ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813f559344f81693cd246f68ab1aa3b4
http://europepmc.org/articles/PMC7567116