Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Carla Osiowy"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionChronic hepatitis D virus (HDV) is associated with rapid progression to severe liver disease. Co-infection with HDV and hepatitis B virus is likely underdiagnosed due to challenges in diagnostic test availability and standardization. With
Externí odkaz:
https://doaj.org/article/d4df36fafdc7450f949152b36252bc7d
Autor:
Sarah J. Robinson, Jamie Borlang, Chelsea G. Himsworth, David L. Pearl, J. Scott Weese, Antonia Dibernardo, Carla Osiowy, Neda Nasheri, Claire M. Jardine
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 9, Pp 1890-1894 (2023)
We tested liver samples from 372 Norway rats (Rattus norvegicus) from southern Ontario, Canada, during 2018–2021 to investigate presence of hepatitis E virus infection. Overall, 21 (5.6%) rats tested positive for the virus. Sequence analysis demons
Externí odkaz:
https://doaj.org/article/3eb564bc9bb946438d5e813556076ca3
Autor:
Shivali S. Joshi, Matthew Sadler, Nishi H. Patel, Carla Osiowy, Kevin Fonseca, Carla S. Coffin
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundHepatitis B virus (HBV)/Hepatitis D Virus (HDV) co-infection increases the risk of severe liver disease compared to HBV mono-infection. Adaptive immune responses to HDV are weakly detectable, and the involvement of innate immunity in the pr
Externí odkaz:
https://doaj.org/article/6833bff9034a45778be0ab23f5d35ef9
Autor:
Alicia Vachon, Grace E. Seo, Nishi H. Patel, Carla S. Coffin, Eric Marinier, Eduardo Eyras, Carla Osiowy
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionSerum hepatitis B virus (HBV) RNA is a promising new biomarker to manage and predict clinical outcomes of chronic hepatitis B (CHB) infection. However, the HBV serum transcriptome within encapsidated particles, which is the biomarker anal
Externí odkaz:
https://doaj.org/article/5dc8392f76ea48b19e398a4bde44ae4f
Autor:
Sheila F O'Brien, Steven J Drews, Antoine Lewin, Carla Osiowy, Michael A Drebot, Christian Renaud
Publikováno v:
Canada Communicable Disease Report, Vol 48, Iss 4, Pp 140-146 (2022)
La pandémie de coronavirus du syndrome respiratoire aigu sévère 2 (SRAS-CoV-2) a galvanisé les études de séroprévalence des donneurs de sang, qui continuent d’éclairer les politiques de santé publique. Nous proposons que les deux fournisse
Externí odkaz:
https://doaj.org/article/94cfabd8dc9d4ebbb11b2f3322e210ce
Autor:
Benard Kibet Langat, Kevin Omondi Ochwedo, Jamie Borlang, Carla Osiowy, Alex Mutai, Fredrick Okoth, Edward Muge, Anton Andonov, Elijah Songok Maritim
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0291378 (2023)
BackgroundThe rapid spread of HBV has resulted in the emergence of new variants. These viral genotypes and variants, in addition to carcinogenic risk, can be key predictors of therapy response and outcomes. As a result, a better knowledge of these em
Externí odkaz:
https://doaj.org/article/ec2cdc15c2334af68c9e787bca8a1344
Autor:
Alicia Vachon, Elizabeth Giles, Nishi Patel, Alexandra Presbitero, Muhammad Atif Zahoor, Carla S. Coffin, Jordan J Feld, Curtis L. Cooper, Carla Osiowy
Publikováno v:
Journal of Clinical Virology Plus, Vol 2, Iss 4, Pp 100126- (2022)
Background: Over 296 million people worldwide are living with chronic Hepatitis B (CHB) infection who require monitoring of viral activity and disease progression. Serum HBV RNA is a promising new biomarker in CHB management. No standardized method f
Externí odkaz:
https://doaj.org/article/37ed952c865c4611bf60dd6b2ba1a9c5
Autor:
François Cholette, Rissa Fabia, Angela Harris, Hannah Ellis, Karla Cachero, Lukas Schroeder, Christine Mesa, Philip Lacap, Corey Arnold, Yannick Galipeau, Marc-André Langlois, Karen Colwill, Anne-Claude Gingras, Allison McGeer, Elizabeth Giles, Jacqueline Day, Carla Osiowy, Yves Durocher, Catherine Hankins, Bruce Mazer, Michael Drebot, John Kim
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10270- (2022)
The extent of the COVID-19 pandemic will be better understood through serosurveys and SARS-CoV-2 antibody testing. Dried blood spot (DBS) samples will play a central role in large scale serosurveillance by simplifying biological specimen collection a
Externí odkaz:
https://doaj.org/article/653e19f1cf87488f961483ffbca13561
Autor:
Carmen Charlton, Jamil Kanji, Vanessa Tran, Julianne Kus, Jonathan Gubbay, Carla Osiowy, Jason Robinson, Inna Sekirov, Michael Drebot, Todd Hatchette, Derek Stein, Nadia El-Gabalawy, Amanda Lang, Lei Jiao, Paul Levett, Heidi Wood, Christian Therrien, L Robbin Lindsay, Muhammad Morshed, Jessica Forbes, Antonia Dibernardo
Publikováno v:
Canada Communicable Disease Report, Vol 47, Iss 4, Pp 171-183 (2021)
The landscape of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic testing is rapidly evolving. While serology testing has limited diagnostic capacity for acute infection, its role in providing population-based information on
Externí odkaz:
https://doaj.org/article/e43ae1b010cc405db886e97ce6d57a3e
Autor:
Carla Osiowy, Ken Swidinsky, Sarah Haylock-Jacobs, Matthew D. Sadler, Scott Fung, David Wong, Gerald Y. Minuk, Karen E. Doucette, Philip Wong, Edward Tam, Curtis Cooper, Alnoor Ramji, Mang Ma, Carmine Nudo, Keith Tsoi, Carla S. Coffin
Publikováno v:
JHEP Reports, Vol 4, Iss 5, Pp 100461- (2022)
Background & Aims: HDV affects 4.5–13% of chronic hepatitis B (CHB) patients globally, yet the prevalence of HDV infection in Canada is unknown. To investigate the prevalence, genotype, demographics, and clinical characteristics of HDV in Canada, w
Externí odkaz:
https://doaj.org/article/e4a36049acb24cf3af2682fa1393c66b