Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Carla Oseroff"'
Autor:
April Frazier, Veronique Schulten, Denise Hinz, Carla Oseroff, John Sidney, Bjoern Peters, Alessandro Sette
Publikováno v:
World Allergy Organization Journal, Vol 7, Iss , Pp - (2014)
We recently identified T cell epitopes associated with human allergic responses. In a majority of cases, responses focused on a few immunodominant epitopes which can be predicted on the basis of MHC binding characteristics. Several observations from
Externí odkaz:
https://doaj.org/article/5e791b642d404421aad5d00a03b16911
Autor:
Maya F Kotturi, Jason Botten, John Sidney, Huynh-Hoa Bui, Lori Giancola, Matt Maybeno, Josie Babin, Carla Oseroff, Valerie Pasquetto, Jason A Greenbaum, Bjoern Peters, Joey Ting, Danh Do, Lo Vang, Jeff Alexander, Howard Grey, Michael J Buchmeier, Alessandro Sette
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000695 (2009)
Arenaviruses are the causative pathogens of severe hemorrhagic fever and aseptic meningitis in humans, for which no licensed vaccines are currently available. Pathogen heterogeneity within the Arenaviridae family poses a significant challenge for vac
Externí odkaz:
https://doaj.org/article/2ceba7f5af924f4aa9e835f3244489bb
Autor:
Francesca Garretti, John Pham, Xiaobo Mao, Julian Agin-Liebes, Ted M. Dawson, Simon Mallal, Curtis McMurtrey, Chelsea Carpenter, Ellen Kanter, April Frazier, John Sidney, Myles B.C. Dillon, Elizabeth J. Phillips, Bjoern Peters, Alessandro Sette, Christopher Liong, Lucien J. Cote, Roy N. Alcalay, Daniela Weiskopf, Carla Oseroff, Cecilia S. Lindestam Arlehamn, William H. Hildebrand, David Sulzer, Valina L. Dawson
Publikováno v:
Nature. 546:656-661
Genetic studies have shown the association of Parkinson's disease with alleles of the major histocompatibility complex. Here we show that a defined set of peptides that are derived from α-synuclein, a protein aggregated in Parkinson's disease, act a
Autor:
John Pham, Sinu Paul, Simon Mallal, Elizabeth J. Phillips, Jason A. Greenbaum, John Sidney, Randi Vita, Alessandro Sette, Carla Oseroff, Bjoern Peters, Denise Hinz
Publikováno v:
Clinical & Experimental Allergy. 46:1194-1205
Background Ragweed is a major cause of seasonal allergy, affecting millions of people worldwide. Several allergens have been defined based on IgE reactivity, but their relative immunogenicity in terms of T cell responses has not been studied. Objecti
Autor:
Rebecca M. Harman, John Sidney, Tobias Bergmann, Jeffrey Shabanowitz, Rebecca L. Tallmadge, Amanda Wriston, Nikolaus Osterrieder, Donald F. Hunt, Alessandro Sette, Carrie Moore, Bjoern Peters, Donald Miller, Carla Oseroff, Douglas F. Antczak
Publikováno v:
Immunogenetics. 67:675-689
Here we describe a detailed quantitative peptide-binding motif for the common equine leukocyte antigen (ELA) class I allele Eqca-1*00101, present in roughly 25 % of Thoroughbred horses. We determined a preliminary binding motif by sequencing endogeno
Publikováno v:
Clinical & Experimental Allergy. 45:1601-1612
House dust mites belong to the most frequent indoor allergen sources worldwide and are potent inducers of perennial asthma and rhinitis [1-3]. Major allergens in house dust are associated with mites of the genus Dermatophagoides [4]. To date, 17 grou
Autor:
Véronique, Schulten, Jason A, Greenbaum, Michael, Hauser, Denise M, McKinney, John, Sidney, Ravi, Kolla, Cecilia S, Lindestam Arlehamn, Carla, Oseroff, Rapheul, Alam, David H, Broide, Fatima, Ferreira, Fatima, Ferreira-Briza, Howard M, Grey, Alessandro, Sette, Bjoern, Peters
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3459-3464
T cells play an important role in the pathogenesis of allergic diseases. However, the proteins considered as potential immunogens of allergenic T-cell responses have traditionally been limited to those that induce IgE responses. Timothy grass (TG) po
Autor:
Thomas J. Scriba, David H. Broide, Randy Taplitz, Alessandro Sette, Denise Hinz, Carla Oseroff, Robert J. Wood, Cecilia S. Lindestam Arlehamn, Veronique Schulten, Denise M. McKinney, Scott Southwood, Bjoern Peters, Willem A. Hanekom, John Sidney, Rafeul Alam
Publikováno v:
Immunogenetics. 65:357-370
Classic ways to determine MHC restriction involve inhibition with locus-specific antibodies and antigen presentation assays with panels of cell lines matched or mismatched at the various loci of interest. However, these determinations are often compl
Autor:
Pandurangan Vijayanand, Eddie A. James, Jason A. Greenbaum, Amin Moghaddas Gholami, Veronique Schulten, Brandie White, Alessandro Sette, Erik Wambre, David H. Broide, Jerome Lane, William W. Kwok, Grégory Seumois, Carla Oseroff, John Sidney, Denise Hinz, Bjoern Peters, Pearl Bakhru
Background Timothy grass (TG) pollen is a common seasonal airborne allergen associated with symptoms ranging from mild rhinitis to severe asthma. Objective The aim of this study was to characterize changes in TG-specific T cell responses as a functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4536e9653db15f4f30694d07a94e224
https://europepmc.org/articles/PMC4846575/
https://europepmc.org/articles/PMC4846575/
Autor:
Randi Vita, David H. Broide, Jason A. Greenbaum, Howard M. Grey, Tess M. Brodie, Victoria Tripple, Bjoern Peters, Scott Southwood, Rafeul Alam, John Sidney, Federica Sallusto, Carla Oseroff, Ravi Kolla, Denise M. McKinney, Alessandro Sette
Publikováno v:
The Journal of Immunology. 189:1800-1811
A panel of 133 allergens derived from 28 different sources, including fungi, trees, grasses, weeds, and indoor allergens, was surveyed utilizing prediction of HLA class II-binding peptides and ELISPOT assays with PBMC from allergic donors, resulting