Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Carla M. Startin"'
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Down syndrome (DS) is the most common genetic cause of intellectual disability (ID) worldwide. Understanding electrophysiological characteristics associated with DS provides potential mechanistic insights into ID, helping inform b
Externí odkaz:
https://doaj.org/article/828ed90e57f8468a8b2d423adf7bdfd1
Autor:
Carla M. Startin, Hana D’Souza, George Ball, Sarah Hamburg, Rosalyn Hithersay, Kate M. O. Hughes, Esha Massand, Annette Karmiloff-Smith, Michael S. C. Thomas, LonDownS Consortium, Andre Strydom
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-13 (2020)
Abstract Background Down syndrome (DS) is associated with variable intellectual disability and multiple health and psychiatric comorbidities. The impact of such comorbidities on cognitive outcomes is unknown. We aimed to describe patterns of physical
Externí odkaz:
https://doaj.org/article/42fed659ef964bd0b3f9ad50702035ff
Autor:
Carla M. Startin, Nicholas J. Ashton, Sarah Hamburg, Rosalyn Hithersay, Frances K. Wiseman, Kin Y. Mok, John Hardy, Alberto Lleó, Simon Lovestone, Lucilla Parnetti, Henrik Zetterberg, Abdul Hye, LonDownS Consortium, André Strydom
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019)
Abstract Background Down syndrome (DS), caused by chromosome 21 trisomy, is associated with an ultra-high risk of dementia due to Alzheimer’s disease (AD), driven by amyloid precursor protein (APP) gene triplication. Understanding relevant molecula
Externí odkaz:
https://doaj.org/article/8822797bba184f3e9f91696674c7dfa9
Autor:
Andre Strydom, Amanda Heslegrave, Carla M. Startin, Kin Y. Mok, John Hardy, Jurgen Groet, Dean Nizetic, Henrik Zetterberg, The LonDownS Consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-5 (2018)
Abstract Background Down syndrome (DS) may be considered a genetic form of Alzheimer’s disease (AD) due to universal development of AD neuropathology, but diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. A potenti
Externí odkaz:
https://doaj.org/article/7f6f6b90ae554b1b950bfb127b77dd79
Autor:
Carla M. Startin, Bryony Lowe, Sarah Hamburg, Rosalyn Hithersay, Andre Strydom, LonDownS Consortium, Elizabeth Fisher, Dean Nizetic, John Hardy, Victor Tybulewicz, Annette Karmiloff-Smith
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Down syndrome (DS) is associated with intellectual disability and an ultra-high risk of developing dementia. Informant ratings are invaluable to assess abilities and related changes in adults with DS, particularly for those with more severe intellect
Externí odkaz:
https://doaj.org/article/0df03a1e409e4ad29d4236f3f13e6da8
Publikováno v:
Frontiers in Psychology, Vol 9 (2019)
Down syndrome (DS) is the most common genetic cause of intellectual disability. There is, however, considerable variation in cognitive abilities between those with DS, with some individuals scoring at floor on some tests, particularly for age-standar
Externí odkaz:
https://doaj.org/article/61093575c9e040bd8eb8ee823a4c1167
Autor:
Carla M. Startin, Sarah Hamburg, Rosalyn Hithersay, Amy Davies, Erin Rodger, Nidhi Aggarwal, Tamara Al-Janabi, André Strydom
Publikováno v:
Wellcome Open Research, Vol 1 (2016)
Background: Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with an ultra-high risk of developing Alzheimer’s disease. However, there is individual variability in the onset of clinical dementia and in bas
Externí odkaz:
https://doaj.org/article/9302829b8cd944928416901c5a7d333a
Autor:
Farah Mgaieth, R. Asaad Baksh, Carla M. Startin, Sarah Hamburg, Rosalyn Hithersay, Sarah Pape, Henrik Zetterberg, Nicholas J. Ashton, Miren Tamayo‐Elizalde, Fedal Saini, Mina Idris, The LonDownS Consortium, Andre Strydom
Publikováno v:
Alzheimer's & Dementia.
Publikováno v:
Journal of Neurodevelopmental Disorders
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-11 (2021)
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-11 (2021)
Background Down syndrome (DS) is the most common genetic cause of intellectual disability (ID) worldwide. Understanding electrophysiological characteristics associated with DS provides potential mechanistic insights into ID, helping inform biomarkers
Publikováno v:
University of Roehampton-PURE
Adults with Down syndrome show premature aging with a high risk of developing dementia, specifically Alzheimer’s disease. Dementia in people with Down syndrome develops in addition to pre-existing intellectual disability, which poses difficulties i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189bffcaa504cbe8a2c25c1db28da4db
https://doi.org/10.1093/oxfordhb/9780190645441.013.27
https://doi.org/10.1093/oxfordhb/9780190645441.013.27