Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carla M. P. Ribeiro"'
Autor:
Deborah M. Cholon, Matthew A. Greenwald, Matthew G. Higgs, Nancy L. Quinney, Susan E. Boyles, Suzanne L. Meinig, John T. Minges, Ashlesha Chaubal, Robert Tarran, Carla M. P. Ribeiro, Matthew C. Wolfgang, Martina Gentzsch
Publikováno v:
Cells, Vol 12, Iss 22, p 2618 (2023)
People with cystic fibrosis (pwCF) suffer from chronic and recurring bacterial lung infections that begin very early in life and contribute to progressive lung failure. CF is caused by mutations in the CF transmembrane conductance regulator (CFTR) ge
Externí odkaz:
https://doaj.org/article/ec9881276a44454fb50ae20ca5572f51
Autor:
Carla M. P. Ribeiro, Matthew G. Higgs, Marianne S. Muhlebach, Matthew C. Wolfgang, Monica Borgatti, Ilaria Lampronti, Giulio Cabrini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 5010 (2023)
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators, a new series of therapeutics that correct and potentiate some classes of mutations of the CFTR, have provided a great therapeutic advantage to people with cystic fibrosis (pwCF).
Externí odkaz:
https://doaj.org/article/f25ecd54218644a7ab1f099fc2b46c81
Autor:
Martina Gentzsch, Deborah M. Cholon, Nancy L. Quinney, Mary E. B. Martino, John T. Minges, Susan E. Boyles, Tara N. Guhr Lee, Charles R. Esther, Carla M. P. Ribeiro
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. The m
Externí odkaz:
https://doaj.org/article/0684a12ec8d9405d9a3000c14aebce39
Autor:
Carla M. P. Ribeiro, Martina Gentzsch
Publikováno v:
Cells, Vol 10, Iss 11, p 3260 (2021)
Defective CFTR biogenesis and activity in cystic fibrosis airways leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. Most cystic fibrosis patients have at least one copy of the F508
Externí odkaz:
https://doaj.org/article/f9f44a2056ee478cb0717cd119c96584
Autor:
Emily A. Hull-Ryde, John T. Minges, Mary E. B. Martino, Takafumi Kato, Jacqueline L. Norris-Drouin, Carla M. P. Ribeiro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3063 (2021)
New anti-inflammatory treatments are needed for CF airway disease. Studies have implicated the endoplasmic reticulum stress transducer inositol requiring enzyme 1α (IRE1α) in CF airway inflammation. The activation of IRE1α promotes activation of i
Externí odkaz:
https://doaj.org/article/59841918a8584e6e93f5b58c54f752f4
Autor:
Renée R. C. E. Schreurs, Athanasios Koulis, Thijs Booiman, Brigitte Boeser-Nunnink, Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Neeltje A. Kootstra, Carla M. S. Ribeiro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell function. Here, we demonstrate a protective role for autophagy in HIV-1 disease p
Externí odkaz:
https://doaj.org/article/3c90dc6926bc447289817ab4859f4bfc
Autor:
Carla M. P. Ribeiro, Bob A. Lubamba
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 118 (2017)
Cystic fibrosis (CF) pulmonary disease is characterized by chronic airway infection and inflammation. The infectious and inflamed CF airway environment impacts on the innate defense of airway epithelia and airway macrophages. The CF airway milieu ind
Externí odkaz:
https://doaj.org/article/028e6d9cb8584529bfcdb24544c6a5c4
Autor:
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Tracy-Jane T. H. D. Eisden, Sterre van Piggelen, Renée R. C. E. Schreurs, Carla M. S. Ribeiro
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dengue virus (DENV), transmitted by infected mosquitoes, is a major public health concern, with approximately half the world’s population at risk for infection. Recent decades have increasing incidence of dengue-associated disease alongside growing
Externí odkaz:
https://doaj.org/article/fbf2b04da0c241539e9d494b0648c9d1
Autor:
Martina, Gentzsch, Deborah M, Cholon, Nancy L, Quinney, Mary E B, Martino, John T, Minges, Susan E, Boyles, Tara N, Guhr Lee, Charles R, Esther, Carla M P, Ribeiro
Publikováno v:
Frontiers in Pharmacology
In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4484d7c6e0c1b38cc6c4db66a9d8a44c
https://pubmed.ncbi.nlm.nih.gov/33859562
https://pubmed.ncbi.nlm.nih.gov/33859562
Autor:
Carla M P, Ribeiro
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 742
The airways are continuously challenged by a variety of stimuli including bacteria, viruses, allergens, and inflammatory factors that act as agonists for G protein-coupled receptors (GPCR). Intracellular calcium (Ca(2+) (i)) mobilization in airway ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ede8bab590a6b5a991240835062e99df
https://pubmed.ncbi.nlm.nih.gov/21547729
https://pubmed.ncbi.nlm.nih.gov/21547729