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pro vyhledávání: '"Carla M. Lema Tomé"'
Autor:
Elodie Angot, Jennifer A Steiner, Carla M Lema Tomé, Peter Ekström, Bengt Mattsson, Anders Björklund, Patrik Brundin
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39465 (2012)
Several people with Parkinson's disease have been treated with intrastriatal grafts of fetal dopaminergic neurons. Following autopsy, 10-22 years after surgery, some of the grafted neurons contained Lewy bodies similar to those observed in the host b
Externí odkaz:
https://doaj.org/article/5c4ac7f09ca84bdf8002a98c409faba1
Publikováno v:
Oncotarget
// Sara Ferluga 1 , Carla Maria Lema Tome 2 , Denise Mazess Herpai 1 , Ralph D’Agostino 3 , Waldemar Debinski 1 1 Department of Cancer Biology, Radiation Oncology and Neurosurgery, Brain Tumor Center of Excellence, Comprehensive Cancer Center of Wa
Autor:
Trevor A. Tyson, Carla M. Lema Tomé, Patrik Brundin, Stefan Grathwohl, Markus Britschgi, Nolwen L. Rey
Publikováno v:
Molecular Neurobiology
Parkinson's disease patients exhibit progressive spreading of aggregated α-synuclein in the nervous system. This slow process follows a specific pattern in an inflamed tissue environment. Recent research suggests that prion-like mechanisms contribut
Autor:
Charles U. Nottingham, Parkson W. Leung, Chelsey Smith, Christopher P. Turner, Amanda S. Beauchamp, Carla M. Lema Tomé
Publikováno v:
NeuroReport. 17:779-783
Schizophrenia, a progressive disorder displaying widespread pathological changes, is associated with the loss of glutamatergic function and selective loss of cytoskeletal proteins, such as MAP2, in regions severely affected by this disease. As schizo
Autor:
Jill Wykosky, W. Todd Lowther, Waldemar Debinski, Roy R. Hantgan, Carla M. Lema Tomé, Sara Ferluga, Enzo Palma
Publikováno v:
The Journal of biological chemistry. 287(17)
The EphA2 receptor is overexpressed in glioblastoma multiforme and has been to shown to contribute to cell transformation, tumor initiation, progression, and maintenance. EphrinA1 (eA1) is a preferred ligand for the receptor. Treatment with monomeric
Autor:
Carla M. Lema Tomé, Kaitlin Blackstone, Chelsey Smith, Clayton T. Bauer, Christopher P. Turner, Adam Leigh, Jamie Busch, Ryan Miller
Publikováno v:
Developmental psychobiology. 50(7)
MK801-induced activation of caspase-3 is developmentally regulated, peaking at postnatal day (P) 7 and decreasing with increasing postnatal age thereafter. Further, at P7, cells displaying activation of caspase-3 lack expression of calcium binding pr
Autor:
Kaitlin Blackstone, Rachael Bryan, Christopher P. Turner, Megan Brady, Clayton T. Bauer, Charles U. Nottingham, Carla M. Lema Tomé, Ryan Miller, Lauren Brown, Adam Leigh, Jamie Busch, Chelsey Smith
Publikováno v:
Developmental psychobiology. 49(6)
Age-dependent, MK801-induced, activated caspase-3 expression in the postnatal brain is generally not observed in neurons expressing calcium-binding proteins (CaBPs), suggesting that apoptosis and calcium buffering are inversely related. In regions su
Publikováno v:
Cancer Research. 70:5465-5465
Glioblastoma multiforme (GBM), a high-grade astrocytoma, is the most common primary brain tumor in adults. GBM is a highly lethal cancer associated with neurological morbidity, and median survival of GBM patients is between 12 to 15 months. Previous