Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carla M P Ribeiro"'
Autor:
Renée R. C. E. Schreurs, Athanasios Koulis, Thijs Booiman, Brigitte Boeser-Nunnink, Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Neeltje A. Kootstra, Carla M. S. Ribeiro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell function. Here, we demonstrate a protective role for autophagy in HIV-1 disease p
Externí odkaz:
https://doaj.org/article/3c90dc6926bc447289817ab4859f4bfc
Autor:
Yunxiang Zhu, Lubna H Abdullah, Sean P Doyle, Kristine Nguyen, Carla M P Ribeiro, Paula A Vasquez, M Gregory Forest, Michael I Lethem, Burton F Dickey, C William Davis
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127267 (2015)
Airway mucin secretion studies have focused on goblet cell responses to exogenous agonists almost to the exclusion of baseline mucin secretion (BLMS). In human bronchial epithelial cell cultures (HBECCs), maximal agonist-stimulated secretion exceeds
Externí odkaz:
https://doaj.org/article/23c76bc6f5944e9f97db43bcc1a2d973
Autor:
Jarrod S Johnson, Martina Gentzsch, Liqun Zhang, Carla M P Ribeiro, Boris Kantor, Tal Kafri, Raymond J Pickles, R Jude Samulski
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002053 (2011)
Barriers to infection act at multiple levels to prevent viruses, bacteria, and parasites from commandeering host cells for their own purposes. An intriguing hypothesis is that if a cell experiences stress, such as that elicited by inflammation, endop
Externí odkaz:
https://doaj.org/article/2b7946ef397d4a6e8d1c9ac73552aa52
Autor:
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Tracy-Jane T. H. D. Eisden, Sterre van Piggelen, Renée R. C. E. Schreurs, Carla M. S. Ribeiro
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dengue virus (DENV), transmitted by infected mosquitoes, is a major public health concern, with approximately half the world’s population at risk for infection. Recent decades have increasing incidence of dengue-associated disease alongside growing
Externí odkaz:
https://doaj.org/article/fbf2b04da0c241539e9d494b0648c9d1
Autor:
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean, Carla M. S. Ribeiro
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTSARS-CoV-2, the causative virus of COVID-19, continues to threaten global public health. COVID-19 is a multi-organ disease, causing not only respiratory distress, but also extrapulmonary manifestations, including gastrointestinal symptoms wit
Externí odkaz:
https://doaj.org/article/20a7f625903a4849b595ebef82383493
Autor:
Nienke H. van Teijlingen, Julia Eder, Ramin Sarrami-Forooshani, Esther M. Zijlstra-Willems, Jan-Paul W. R. Roovers, Elisabeth van Leeuwen, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Vaginal inflammation increases the risk for sexual HIV-1 transmission but underlying mechanisms remain unclear. In this study we assessed the impact of immune activation on HIV-1 susceptibility of primary human vaginal Langerhans cells (LCs)
Externí odkaz:
https://doaj.org/article/a7e0a62b0e6646fa90b1a7b878945d4e
Autor:
Deborah M. Cholon, Matthew A. Greenwald, Matthew G. Higgs, Nancy L. Quinney, Susan E. Boyles, Suzanne L. Meinig, John T. Minges, Ashlesha Chaubal, Robert Tarran, Carla M. P. Ribeiro, Matthew C. Wolfgang, Martina Gentzsch
Publikováno v:
Cells, Vol 12, Iss 22, p 2618 (2023)
People with cystic fibrosis (pwCF) suffer from chronic and recurring bacterial lung infections that begin very early in life and contribute to progressive lung failure. CF is caused by mutations in the CF transmembrane conductance regulator (CFTR) ge
Externí odkaz:
https://doaj.org/article/ec9881276a44454fb50ae20ca5572f51
Autor:
Alexandra P. M. Cloherty, Nienke H. van Teijlingen, Tracy-Jane T. H. D. Eisden, John L. van Hamme, Anusca G. Rader, Teunis B. H. Geijtenbeek, Renée R. C. E. Schreurs, Carla M. S. Ribeiro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 persists in long-lived tissue-derived dendritic cells (DCs)
Externí odkaz:
https://doaj.org/article/747ad914bf0d46c9860d30f8766e3ccd
Autor:
Martina Gentzsch, Deborah M. Cholon, Nancy L. Quinney, Mary E. B. Martino, John T. Minges, Susan E. Boyles, Tara N. Guhr Lee, Charles R. Esther, Carla M. P. Ribeiro
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. The m
Externí odkaz:
https://doaj.org/article/0684a12ec8d9405d9a3000c14aebce39
Autor:
Carla M. P. Ribeiro, Martina Gentzsch
Publikováno v:
Cells, Vol 10, Iss 11, p 3260 (2021)
Defective CFTR biogenesis and activity in cystic fibrosis airways leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and inflammation. Most cystic fibrosis patients have at least one copy of the F508
Externí odkaz:
https://doaj.org/article/f9f44a2056ee478cb0717cd119c96584