Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carla Jennewein"'
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2173-2181 (2009)
Macrophages ingesting apoptotic cells attenuate inflammatory responses, such as reactive oxygen species (ROS) generation. In atherosclerosis, ongoing inflammation and accumulation of apoptotic/necrotic material are observed, suggesting defects of pha
Externí odkaz:
https://doaj.org/article/7a96e0c22cdf454a84429a0270de211c
Autor:
Anja Urbschat, Kai Zacharowski, Nicholas Obermüller, Katrin Rupprecht, Daniela Penzkofer, Carla Jennewein, Nguyen Tran, Bertram Scheller, Stefanie Dimmeler, Patrick Paulus
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84432 (2014)
Disruption of the renal endothelial integrity is pivotal for the development of a vascular leak, tissue edema and consequently acute kidney injury. Kidney ischemia amplifies endothelial activation and up-regulation of pro-inflammatory mechanisms. Aft
Externí odkaz:
https://doaj.org/article/9b9c95015f8b4b5b84c3849bcd0bd1ae
Autor:
Klemens König, David Köhler, Tiago Granja, Carla Jennewein, Nguyen Tran, Valbona Mirakaj, Friedemann Kröhnert, Peter Rosenberger
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41085 (2012)
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of
Externí odkaz:
https://doaj.org/article/84677716c31c4a648354c9ab5923008d
Autor:
Dania Fischer, Christian F Weber, Markus Müller, Carla Jennewein, Kai Zacharowski, Anja Urbschat, Julian Büssow, Patrick Meybohm
Publikováno v:
Transfusion. 57:2701-2711
BACKGROUND The pathomechanisms of morbidity due to blood transfusions are not yet entirely understood. Elevated levels of red blood cell-derived microparticles (RMPs) are found in coagulation-related pathologies and also in stored blood. Previous res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60ef81a536eb0b9cb6e84b3f7c1083a2
https://doi.org/10.1111/trf.14268
https://doi.org/10.1111/trf.14268
Autor:
Waldemar Kanczkowski, Bertram Scheller, Lars Heerdegen, Stefan R. Bornstein, Nguyen Tran, Ajith Kantharajah, Kai Zacharowski, Stefan Dröse, Carla Jennewein
Publikováno v:
Critical Care Medicine. 44:e190-e199
OBJECTIVES Sepsis and septic shock are commonly present in the ICU and accompanied by significant morbidity, mortality, and cost. The frequency of secondary adrenal insufficiency in sepsis remains open to debate and a challenge to identify and treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1908bcd547d0b018595a46d4a1acd8ce
https://doi.org/10.1097/ccm.0000000000001373
https://doi.org/10.1097/ccm.0000000000001373
Publikováno v:
Transfusion. 56:146-152
BACKGROUND Basic research on the pathomechanisms of transfusion-related adverse events depends on murine transfusion models, in which leukoreduction (LR) is a prevalent standard. The commonly used neonatal LR filter (LRF) is associated with considera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017b5459aba60a7e062c71051e9b2eba
https://doi.org/10.1111/trf.13335
https://doi.org/10.1111/trf.13335
Autor:
Peter Rosenberger, Klemens König, Mariella Schneider, Vasudharani Devanathan, Tiago Granja, Linda Marth, Carla Jennewein, Alexander Zarbock, Jan Roissant, David Köhler
Publikováno v:
European Journal of Immunology. 44:2648-2658
Acute inflammation is the pathophysiological basis of important clinical conditions associated with organ failure. The initial inflammatory response is controlled by the chemokine system, yet recent data have indicated that the neuronal guidance cues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f817a515eecbd6729ffd87f51535944
https://doi.org/10.1002/eji.201343968
https://doi.org/10.1002/eji.201343968
Publikováno v:
Biomarkers. 16:S11-S21
The endothelial integrity, as mechanical barrier against microorganisms and as natural "anticoagulant", is crucial for physiologic organ function. Systemic activation of the endothelium upon inflammation, sepsis, and septic shock is always ending in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd303e5ae8b8c699418cdd9d9408180d
https://doi.org/10.3109/1354750x.2011.587893
https://doi.org/10.3109/1354750x.2011.587893
Publikováno v:
Journal of Cell Science. 123:192-201
PPARgamma exerts significant anti-inflammatory signaling properties in monocytes and macrophages, which are affected by its intracellular localization. Based on our previous report, which showed that cytosolic localization of PPARgamma attenuates PKC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9488d5a3a117a37cc8bcbe6d75b41447
https://doi.org/10.1242/jcs.055475
https://doi.org/10.1242/jcs.055475
Publikováno v:
Biological Chemistry. 390:379-390
The efficient execution of apoptotic cell death with the clearance of apoptotic debris by phagocytes is a key regulatory mechanism ensuring tissue homeostasis. Failure in this execution program contributes to the pathogenesis of many human diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a1948b398bb485f472c7aac7c312e0
https://doi.org/10.1515/bc.2009.048
https://doi.org/10.1515/bc.2009.048