Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Carla Hebert"'
Autor:
Shama R. Iyer, Carla Hebert, Joseph P. Stains, Ryan E. Tomlinson, Megan C. Moorer, Max Chason
Publikováno v:
Journal of Cell Science.
In skeletal tissue, loss or mutation of the gap junction protein connexin 43 (Cx43, also known as GJA1) in cells of the osteoblast lineage leads to a profound cortical bone phenotype and defective tissue remodeling. There is mounting evidence in bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f71453e8e6a2f1b46944682ee957c3c
https://doi.org/10.1242/jcs.197285
https://doi.org/10.1242/jcs.197285
Autor:
Joseph P. Stains, Carla Hebert
Publikováno v:
Journal of Cellular Biochemistry. 114:2542-2550
The cytoplasmic C-terminus of connexin43 (Cx43) interacts with numerous signaling complexes. We hypothesize that signal complex docking to the Cx43 C-terminus (CT) is required to propagate the molecules being shared by gap junctions. We have previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843280892dab5870a57a9970c487c8d5
https://doi.org/10.1002/jcb.24603
https://doi.org/10.1002/jcb.24603
Publikováno v:
Journal of Bone and Mineral Research. 28:1468-1477
Connexin43 (Cx43) plays a critical role in osteoblast function and bone mass accrual, yet the identity of the second messengers communicated by Cx43 gap junctions, the targets of these second messengers and how they regulate osteoblast function remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2ef767a23fba7f76ad1c79bc5575ca1
https://doi.org/10.1002/jbmr.1867
https://doi.org/10.1002/jbmr.1867
Autor:
Joseph P. Stains, Rishi R. Gupta, Carla Hebert, Atum M. Buo, Florence Lima, Corinne Niger, David Yoo
Publikováno v:
Bone. 49:683-692
The transcription factor osterix (Osx/Sp7) is required for osteogenic differentiation and bone formation in vivo. While Osx can act at canonical Sp1 DNA-binding sites and/or interact with NFATc1 to cooperatively regulate transcription in some osteobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e0e50e3dc387bdbd4d36f2e9defc2d
https://doi.org/10.1016/j.bone.2011.07.027
https://doi.org/10.1016/j.bone.2011.07.027
Publikováno v:
Biochemical and Biophysical Research Communications. 402:258-264
The purpose of this study was to characterize the molecular phenotype that occurs during the profound morphological shift of cultured osteogenic cells upon treatment with fibroblast growth factor-2 (FGF2). A time course of treatment with FGF2 was per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff63615be5dd466eacb456caaf692cc
https://doi.org/10.1016/j.bbrc.2010.10.011
https://doi.org/10.1016/j.bbrc.2010.10.011
Autor:
Robert V O'Toole, Adam H. Hsieh, Leah Gitajn, Carla Hebert, David Yoo, Rishi R. Gupta, Joseph P. Stains, Yu-Kwan Chan, Hyunchul Kim
Publikováno v:
Bone Research
The mechanical environment is known to influence fracture healing. We speculated that connexin43 (Cx43) gap junctions, which impact skeletal homeostasis, fracture healing and the osteogenic response to mechanical load, may play a role in mediating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617078292ca3dc4537c00cee530d22aa
https://doi.org/10.1038/boneres.2015.7
https://doi.org/10.1038/boneres.2015.7
Autor:
Anne W. Hamburger, Nikolaos G. Nikitakis, Carla Hebert, Hessam Siavash, Mark A. Reynolds, John J. Sauk
Publikováno v:
British Journal of Cancer
Activation of peroxisome proliferator-activated receptor gamma (PPARγ) has been linked to induction of differentiation, cell growth inhibition and apoptosis in several types of human cancer. However, the possible effects of PPARγ agonists on human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825e94651b50581d157c6f3a052a8c2d
http://europepmc.org/articles/PMC2376283
http://europepmc.org/articles/PMC2376283
Publikováno v:
Journal of Cellular Biochemistry. 78:251-263
Previously we have shown (Hebert et al. [1999] J. Cell Biochem. 73:248-258) that among many cell lines the CBP2 gene product, Hsp47, eludes its retention receptor, erd2P, resulting in the appearance of Hsp47 on the cell surface associated with the te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519dd5e1a2ed522a4c7a8850138689f7
https://doi.org/10.1002/(sici)1097-4644(20000801)78:2<251::aid-jcb8>3.0.co
https://doi.org/10.1002/(sici)1097-4644(20000801)78:2<251::aid-jcb8>3.0.co
Publikováno v:
Journal of Cellular Biochemistry. 73:248-258
Hsps expressed on the cell surface have been associated with tumor invasiveness and used as targets for molecular surveillance. The present study utilized four human oral squamous cell carcinoma cells lines, SCC-4, SCC-9, SCC-15, SCC-25, the murine e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92059e96b3117b3a4e472438d692bea
https://doi.org/10.1002/(sici)1097-4644(19990501)73:2<248::aid-jcb11>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19990501)73:2<248::aid-jcb11>3.0.co
Publikováno v:
Connective Tissue Research. 37:105-119
Hsp47 is a novel glycoprotein that binds specifically to procollagen and is retained in the ER by its COOH-terminus RDEL peptide sequence (Satoh, M. et al. Jol. Cell Biol. 1996; 133: 469-83). In this paper, we report that erd2P, the KDEL receptor, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b326a22a1aacc4fe8491bade87fe7cb
https://doi.org/10.3109/03008209809028904
https://doi.org/10.3109/03008209809028904