Výsledky vyhledávání - "Carla Domuro"

Akademický článek

Blockade of novel immune checkpoints and new therapeutic combinations to boost antitumor immunity

Autor: Adrià Archilla-Ortega, Carla Domuro, Juan Martin-Liberal, Purificación Muñoz

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)

Abstract Immunotherapy has emerged as a promising strategy for boosting antitumoral immunity. Blockade of immune checkpoints (ICs), which regulate the activity of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells has proven clinical benefi

Externí odkaz: https://doaj.org/article/7d32ca9e6ba94ab49d287602e5776a86

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CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein

Autor: Edurne Gallastegui, Josep Saura, Carla Domuro, Oriol Bachs, Mario Ezquerra, Carme Solà, María-José Martí, Leonardo Márquez-Kisinousky, Tony Valente, Guido Dentesano, Marco Straccia, Jonatan Martinez-Martin, Yaroslau Compta, Rubén Fernández-Santiago

Publikováno v: Cell Death Differ
Digital.CSIC. Repositorio Institucional del CSIC
instname

α-Synuclein is the main component of Lewy bodies, the intracellular protein aggregates representing the histological hallmark of Parkinson’s disease. Elevated α-synuclein levels and mutations in SNCA gene are associated with increased risk for Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e35ec0608114cdf37c13430040085fe
http://hdl.handle.net/10261/206151

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p27Kip1 regulates alpha-synuclein expression

Autor: Serena Orlando, Carla Domuro, Isabel Fariñas, Oriol Bachs, Edurne Gallastegui, Laura Sin, Maria Jesús Pujol, Rosa Aligué, Joan Serratosa, Arnaud Besson, Alejandra Larrieux, Jonatan Martinez, José Manuel Morante-Redolat

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Oncotarget
Oncotarget, Impact journals, 2018, 9 (23), pp.16368-16379. ⟨10.18632/oncotarget.24687⟩
Dipòsit Digital de la UB
Universidad de Barcelona

Alpha-synuclein (α-SYN) is the main component of anomalous protein aggregates (Lewy bodies) that play a crucial role in several neurodegenerative diseases (synucleinopathies) like Parkinson’s disease and multiple system atrophy. However, the mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ee65911b9c2f60fd93ba698f8ae3f4
http://hdl.handle.net/10261/177158

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