Metformin improves ovarian follicle dynamics by reducing theca cell proliferation and CYP-17 expression in an androgenized rat model

Autor: Roberta Rassi Mahamed, Carla Cristina Maganhin, Gisela Rodrigues Silva Sasso, Manuel de Jesus Simões, Maria Candida Pinheiro Baracat, Edmund Chada Baracat, José Maria Soares

Publikováno v: Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-10 (2018)

Abstract Background Metformin influences insulin receptor signaling, which might interfere with the proliferation of ovarian follicular structures and steroidogenesis. We hypothesize that reductions in glucose and insulin levels might interfere with

Externí odkaz: https://doaj.org/article/e2536930dd7a4a909ad059db8beb773e

Evidence that Melatonin Increases Inhibin Beta-A and Follistatin Gene Expression in Ovaries of Pinealectomized Rats

Autor: Camilla Maganhin Luquetti, José Cipolla-Neto, Maria Cândida Pinheiro Baracat, Katia C. Carvalho, Adriana Aparecida Ferraz Carbonel, Edmund Chada Baracat, Manuel Simões, Isadora Braga Seganfredo, Carla Cristina Maganhin, Ricardo Simoes, José Maria Soares-Jr, Manoel João Batista Castello Girão

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Melatonin plays an important role in the regulation of ovarian function including oocyte maturation in different mammalian species. Many studies indicate that melatonin has an impact on the ovarian function of a variety of ovarian cells. However, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c43cd02df9ee80735885fdbc9798f57
https://doi.org/10.1007/s43032-020-00162-1

Assessing the benefits of rosiglitazone in women with polycystic ovary syndrome through its effects on insulin-like growth factor 1, insulin-like growth factor-binding protein-3 and insulin resistance: a pilot study

Autor: José Gomes Batista, José Maria Soares-Jr, Carla Cristina Maganhin, Ricardo Santos Simões, Geraldez Tomaz, Edmund Chada Baracat

Publikováno v: Clinics, Vol 67, Iss 3, Pp 283-287 (2012)

Externí odkaz: https://doaj.org/article/38cc6ec2ffd448b0ab13e6453b3c490a

Rat pinealectomy: a modified direct visual approach Pinealectomia em ratos: técnica modificada com visualização direta

Autor: Carla Cristina Maganhin, Ricardo Santos Simões, Luiz Fernando Portugal Fuchs, Ricardo Martins Oliveira-Filho, Manuel de Jesus Simões, Joaquim Evêncio Neto, Edmund Chada Baracat, José Maria Soares Júnior

Publikováno v: Acta Cirúrgica Brasileira, Vol 24, Iss 4, Pp 321-324 (2009)

PURPOSE: To report a new, direct visual approach for rat pinealectomy. METHODS: Eighty adult female rats (Rattus norvegicus albinus EPM-1 strain) were weighted and anesthetized intraperitoneally with 15 mg/kg xylazine and 30 mg/kg ketamine. The anima

Externí odkaz: https://doaj.org/article/4ce2f90b810f442f92a2c300e6d54f12

Melatonin effects on ovarian follicular cells: a systematic review

Autor: Eduardo Carvalho de Arruda Veiga, Maria Cândida Pinheiro Baracat, Camila de Oliveira Nuñes, Carla Cristina Maganhin, Edmund Chada Baracat, José Cipolla Neto, Isabela Pasqualini Minguini, José Maria Soares Júnior, Camila Maganhin Luquetti, Ricardo Simoes

Publikováno v: Revista da Associação Médica Brasileira v.65 n.8 2019
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Volume: 65, Issue: 8, Pages: 1122-1127, Published: 12 SEP 2019
Revista da Associação Médica Brasileira, Vol 65, Iss 8, Pp 1122-1127

SUMMARY Melatonin is known for its effects on both the sleep and reproductive system of mammals. The latter has melatonin receptors type 1 and 2, which act to regulate, among other things, cyclic AMP. Notwithstanding all the literature data, there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455d02a0dd1e454b63a3b00d7a19d778
https://doi.org/10.1590/1806-9282.65.8.1122