Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Carla Cerami Hand"'
1
Akademický článek
Ketamine does not produce relief of neuropathic pain in mice lacking the β-common receptor (CD131).
Autor: Maarten Swartjes, Marieke Niesters, Lara Heij, Ann Dunne, Leon Aarts, Carla Cerami Hand, Hyung-Suk Kim, Michael Brines, Anthony Cerami, Albert Dahan
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71326 (2013)
Neuropathic pain (NP) is a debilitating condition associated with traumatic, metabolic, autoimmune and neurological etiologies. Although the triggers for NP are diverse, there are common underlying pathways, including activation of immune cells in th
Externí odkaz: https://doaj.org/article/b8a27470a0bf4b78b726c06cdbaeb306
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2
Akademický článek
Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model.
Autor: Patricia Ferrer, Abhai K Tripathi, Martha A Clark, Carla Cerami Hand, Hugh Young Rienhoff, David J Sullivan
Publikováno v: PLoS ONE, Vol 7, Iss 5, p e37171 (2012)
Iron chelators for the treatment of malaria have proven therapeutic activity in vitro and in vivo in both humans and mice, but their clinical use is limited by the unsuitable absorption and pharmacokinetic properties of the few available iron chelato
Externí odkaz: https://doaj.org/article/14d823b1c85a424fb5a84c073bf0d37d
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3
Treatment of Mild Traumatic Brain Injury with an Erythropoietin-Mimetic Peptide
Autor: Carla Cerami Hand, Raymond J. Grill, Samson Sujit Kumar Gaddam, H. Julia Hannay, Claudia S. Robertson, Tian Siva Tian, Robert Garcia
Publikováno v: Journal of Neurotrauma. 30:765-774
Mild traumatic brain injury (mTBI) results in an estimated 75–90% of the 1.7 million TBI-related emergency room visits each year. Post-concussion symptoms, which can include impaired memory problems, may persist for prolonged periods of time in a f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6004f55c37e648df7d9949475539d790
https://doi.org/10.1089/neu.2012.2431
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4
Parasite maturation and host serum iron influence the labile iron pool of erythrocyte stagePlasmodium falciparum
Autor: Martha A. Clark, Nancy C. Fisher, Carla Cerami Hand, Raj S. Kasthuri
Publikováno v: British Journal of Haematology. 161:262-269
Iron is a critical and tightly regulated nutrient for both the malaria parasite and its human host. The importance of the relationship between host iron and the parasite has been underscored recently by studies showing that host iron supplementation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f42fb567756027f9870708203e0b7f
https://doi.org/10.1111/bjh.12234
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5
Neuroprotection with an Erythropoietin Mimetic Peptide (pHBSP) in a Model of Mild Traumatic Brain Injury Complicated by Hemorrhagic Shock
Autor: Claudia S. Robertson, Raymond J. Grill, Tian Siva Tian, Leela Cherian, H. Julia Hannay, Mahek Shah, Carla Cerami Hand, Jovany Cruz Navarro, Robert Garcia
Publikováno v: Journal of Neurotrauma. 29:1156-1166
Pyroglutamate helix B surface peptide (pHBSP) is an 11 amino acid peptide, designed to interact with a novel cell surface receptor, composed of the classical erythropoietin (EPO) receptor disulfide linked to the beta common receptor. pHBSP has the cy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd75b5b863e1c7032ee4e299e7a3521b
https://doi.org/10.1089/neu.2011.1827
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6
Quantification of the Burden and Consequences of Pregnancy-Associated Malaria in the Democratic Republic of the Congo
Autor: Jane P. Messina, Kashamuka Mwandagalirwa, Jérémie Muwonga, Steven R. Meshnick, Benjamin Atua, Michael Emch, Carla Cerami Hand, Antoinette K. Tshefu, Steve M. Taylor, Anna Maria van Eijk, Feiko O. ter Kuile
Publikováno v: Journal of infectious diseases, 204(11), 1762-1771. Oxford University Press
Background. Pregnancy-associated malaria (PAM) produces poor birth outcomes, but its prevalence is commonly estimated in convenience samples. Methods. We assessed the prevalence of malaria using real-time polymerase chain reaction (PCR) and estimated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5579a1e2c72267029bb7927ec89aec9e
https://doi.org/10.1093/infdis/jir625
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9
Promises and Pitfalls in Erythopoietin-Mediated Tissue Protection: Are Nonerythropoietic Derivatives a Way Forward?
Autor: Michael Brines, Carla Cerami Hand
The essential biological role of erythropoietin (EPO) in maintaining erythrocyte mass has been well understood for many years. Although EPO is required for the maturation of red cells, it also has strong procoagulant effects on the vascular endotheli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5c29dc04ba572c3629b8c24ff63ef0
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