Use of Self-Collected Saliva Samples for the Detection of SARS-CoV-2

Autor: Kehinde Sogbesan, Taiwo Sogbesan, D Jane Hata, Edward L White, Wyeth Daniel, Samuel L Gasson, Dylan S Jones, Brittany R Vicari, Carleen P Van Siclen, Carla Palmucci, Christopher P Marquez, Mark A Parkulo, Kent R Thielen, Aziza Nassar

Publikováno v: Laboratory Medicine. 53:580-584

Objective Using a US Food and Drug Administration (FDA) emergency use authorization (EUA) reverse transcription polymerase chain reaction (RT-PCR) method, we examined the analytic performance accuracy of saliva specimens as compared to nasopharyngeal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fce00bf40f76ffb12dfab304f00905
https://doi.org/10.1093/labmed/lmac051

Performance Accuracy of a Laboratory-Developed Real-Time RT-PCR Method for Detection of SARS-CoV-2 in Self-Collected Saliva Specimens

Autor: D Jane, Hata, Edward L, White, Michaela M, Bridgeman, Samuel L, Gasson, Dylan S, Jones, Brittany R, Vicari, Carleen P, Van Siclen, Carla, Palmucci, Christopher P, Marquez, Mark A, Parkulo, Kent R, Thielen, Aziza, Nassar

Publikováno v: Annals of clinical and laboratory science. 51(6)

The ongoing COVID-19 pandemic caused by SARS-CoV-2 has challenged diagnostic laboratories to re-examine traditional methods for collecting specimens and sample types used in molecular testing. Our goal was to demonstrate that saliva can be used for d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64d172ea3878cc35a6783aea038bb584
https://pubmed.ncbi.nlm.nih.gov/34921026

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

Autor: Timothy M. Miller, Jon B. Toledo, Jennifer Farren, Jeffrey D. Rothstein, John Q. Trojanowski, Luc Pregent, Michael G. Heckman, Alessandro Prelle, Aliesha D. O’Raw, Beth K. Rush, Bryan J. Traynor, Laura Braun, Matthew D. Disney, Yari Carlomagno, Veronique V. Belzil, Antonia Ratti, Lilia J. Tabassian, Monica Castanedes-Casey, Dennis W. Dickson, Michael Tierney, John C. van Swieten, Adam L. Boxer, Jeannie Chew, Lauren Elman, Murray Grossman, Emilie A. Perkerson, Mercedes Prudencio, Ana M. Caputo, Frank Rigo, Lillian M. Daughrity, Casey Cook, Otto Pedraza, James D. Berry, David Lacomis, Christina Fournier, Jennifer Jockel-Balsarotti, Leonard Petrucelli, Giovanna Antognetti, Marka van Blitterswijk, Lindsey R. Hayes, Robert H. Brown, Joanne Wuu, Kevin B. Boylan, Jimei Tong, Edythe Wiggs, Amelia Robertson, Linda Rousseau, Karen Jansen-West, Mary Kay Floeter, Yuping Song, John D. Fryer, Tania D Gendron, Robert Bowser, Barbara Poletti, Jennifer D. McBride, Shafeeq Ladha, Federica Solca, Alexander McCampbell, Leo McCluskey, Bruce L. Miller, Weixing Yang, Rosa Rademakers, Virginia Phillips, Chris W. Lee, Mei Yue, Denitza Raitcheva, Carla Palmucci, Jonathan D. Glass, Nancy N. Diehl, Vincenzo Silani, Jeannette N. Stankowski, Pamela Desaro, Cinzia Tiloca, Claudia Morelli, Abhishek Datta, William T. Hu, Yong Jie Zhang, Michael Benatar, Christine Ambrose

Publikováno v: Science Translational Medicine, 9(383):eaai7866. American Association for the Advancement of Science
Science translational medicine, vol 9, iss 383
Science translational medicine

There is no effective treatment for amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease. However, discovery of a G(4)C(2) repeat expansion in the C9ORF72 gene as the most common genetic cause of ALS has opened up new avenues for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476c09df1772869d16b8d12d922e0b01
https://doi.org/10.1126/scitranslmed.aai7866