Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Carla, Cicala"'
Autor:
Caterina Giraulo, Lavinia Orlando, Elva Morretta, Antonia Voli, Paola Plaitano, Carla Cicala, Eugen Potaptschuk, Christa E. Müller, Alessandra Tosco, Maria Chiara Monti, Silvana Morello
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117033- (2024)
Melanoma cells express high levels of CD73 that produce extracellular immunosuppressive adenosine. Changes in the CD73 expression occur in response to tumor environmental factors, contributing to tumor phenotype plasticity and therapeutic resistance.
Externí odkaz:
https://doaj.org/article/10068ff471c8423bb64dd250e802a916
Autor:
Barbara Kutryb-Zając, Ada Kawecka, Khrystyna Nasadiuk, Alicja Braczko, Klaudia Stawarska, Elisabetta Caiazzo, Patrycja Koszałka, Carla Cicala
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115184- (2023)
Adenosine is an endogenous nucleoside that regulates many physiological and pathological processes. It is derived from either the intracellular or extracellular dephosphorylation of adenosine triphosphate and interacts with cell-surface G-protein-cou
Externí odkaz:
https://doaj.org/article/738b3dd0f90a46bbad51ed4bdf06bbc4
Autor:
Carla Cicala, Silvana Morello
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11055 (2023)
Tissue inflammation is a dynamic process that develops step by step, in response to an injury, to preserve tissue integrity [...]
Externí odkaz:
https://doaj.org/article/d4f9340291574b388ffbdd1e1222e61b
Autor:
Ida Cerqua, Konstantin Neukirch, Michela Terlizzi, Elisabetta Granato, Elisabetta Caiazzo, Carla Cicala, Armando Ialenti, Raffaele Capasso, Oliver Werz, Rosalinda Sorrentino, Denis Seraphin, Jean-Jacques Helesbeux, Giuseppe Cirino, Andreas Koeberle, Fiorentina Roviezzo, Antonietta Rossi
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106250- (2022)
Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously formed metabolites (long-chain metabolites, LCM). Here, we have evaluated the role of LCM in relieving asthma features. To
Externí odkaz:
https://doaj.org/article/cde91b43354b4b5a972cc24aaddca0c7
Autor:
Elisabetta Caiazzo, Ida Cerqua, Roberta Turiello, Maria Antonietta Riemma, Giacomo De Palma, Armando Ialenti, Fiorentina Roviezzo, Silvana Morello, Carla Cicala
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 697 (2022)
Ecto-5′-nucleotidase (CD73), the ectoenzyme that together with CD39 is responsible for extracellular ATP hydrolysis and adenosine accumulation, regulates immune/inflammatory processes by controlling innate and acquired immunity cell functions. We p
Externí odkaz:
https://doaj.org/article/9c7f1405352345f4a50e8388e5517f73
Autor:
Elisabetta Caiazzo, Ida Cerqua, Maria Antonietta Riemma, Roberta Turiello, Armando Ialenti, Jurgen Schrader, Giuseppe Fiume, Carmen Caiazza, Fiorentina Roviezzo, Silvana Morello, Carla Cicala
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual response to allergens are dependent upon environmental and host factors. Early studies perfor
Externí odkaz:
https://doaj.org/article/2da775285fde4da3ba03c8b1da7b5268
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
There is evidence that an imbalance of extracellular purine levels may be associated with increased cardiovascular risk. Platelets play a pivotal role in vascular homeostasis and thrombosis and are important source of purine nucleotides and nucleosid
Externí odkaz:
https://doaj.org/article/a2e5c0ef81734f24b04848082269776f
Publikováno v:
Cells, Vol 10, Iss 9, p 2223 (2021)
There is increasing evidence for a link between inflammation and thrombosis. Following tissue injury, vascular endothelium becomes activated, losing its antithrombotic properties whereas inflammatory mediators build up a prothrombotic environment. Pl
Externí odkaz:
https://doaj.org/article/453faab2782d49af83e33f5f036e5d09
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The ecto-5’-nucleotidase (ecto-5’NT/CD73) represents a crucial enzyme for endogenous adenosine generation. Several findings have shown that CD73 plays an important role in regulating vascular permeability and immune cell function. Adenosine 5’-
Externí odkaz:
https://doaj.org/article/82385707d5ad455ebbf75bd7a54f8616
Autor:
Fiorentina Roviezzo, Antonietta Rossi, Elisabetta Caiazzo, Pierangelo Orlando, Maria A. Riemma, Valentina M. Iacono, Andrea Guarino, Armando Ialenti, Carla Cicala, Alessio Peritore, Raffaele Capasso, Vincenzo Di Marzo, Angelo A. Izzo
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
One important risk factor for the development of asthma is allergen sensitization. Recent increasing evidence suggests a prominent role of mast cells in asthma pathophysiology. Since Palmitoylethanolamide (PEA), an endogenous lipid mediator chemicall
Externí odkaz:
https://doaj.org/article/84d8cb0cc2214f2a86ffc0e1706eff38