Výsledky vyhledávání - "Carla, Cicala"

Akademický článek

Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge

Autor: Elisabetta Caiazzo, Ida Cerqua, Roberta Turiello, Maria Antonietta Riemma, Giacomo De Palma, Armando Ialenti, Fiorentina Roviezzo, Silvana Morello, Carla Cicala

Publikováno v: Biomolecules, Vol 12, Iss 5, p 697 (2022)

Ecto-5′-nucleotidase (CD73), the ectoenzyme that together with CD39 is responsible for extracellular ATP hydrolysis and adenosine accumulation, regulates immune/inflammatory processes by controlling innate and acquired immunity cell functions. We p

Externí odkaz: https://doaj.org/article/9c7f1405352345f4a50e8388e5517f73

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Akademický článek

Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)

Autor: Elisabetta Caiazzo, Ida Cerqua, Maria Antonietta Riemma, Roberta Turiello, Armando Ialenti, Jurgen Schrader, Giuseppe Fiume, Carmen Caiazza, Fiorentina Roviezzo, Silvana Morello, Carla Cicala

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual response to allergens are dependent upon environmental and host factors. Early studies perfor

Externí odkaz: https://doaj.org/article/2da775285fde4da3ba03c8b1da7b5268

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Akademický článek

Thrombo-Inflammation: A Focus on NTPDase1/CD39

Autor: Silvana Morello, Elisabetta Caiazzo, Roberta Turiello, Carla Cicala

Publikováno v: Cells, Vol 10, Iss 9, p 2223 (2021)

There is increasing evidence for a link between inflammation and thrombosis. Following tissue injury, vascular endothelium becomes activated, losing its antithrombotic properties whereas inflammatory mediators build up a prothrombotic environment. Pl

Externí odkaz: https://doaj.org/article/453faab2782d49af83e33f5f036e5d09

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Akademický článek

Ectonucleoside Triphosphate Diphosphohydrolase-1/CD39 Affects the Response to ADP of Female Rat Platelets

Autor: Elisabetta Caiazzo, Rossella Bilancia, Antonietta Rossi, Armando Ialenti, Carla Cicala

Publikováno v: Frontiers in Pharmacology, Vol 10 (2020)

There is evidence that an imbalance of extracellular purine levels may be associated with increased cardiovascular risk. Platelets play a pivotal role in vascular homeostasis and thrombosis and are important source of purine nucleotides and nucleosid

Externí odkaz: https://doaj.org/article/a2e5c0ef81734f24b04848082269776f

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Akademický článek

The Ecto-5’-Nucleotidase/CD73 Inhibitor, α,β-Methylene Adenosine 5’-Diphosphate, Exacerbates Carrageenan-Induced Pleurisy in Rat

Autor: Elisabetta Caiazzo, Silvana Morello, Rosa Carnuccio, Armando Ialenti, Carla Cicala

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

The ecto-5’-nucleotidase (ecto-5’NT/CD73) represents a crucial enzyme for endogenous adenosine generation. Several findings have shown that CD73 plays an important role in regulating vascular permeability and immune cell function. Adenosine 5’-

Externí odkaz: https://doaj.org/article/82385707d5ad455ebbf75bd7a54f8616

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Akademický článek

Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse

Autor: Fiorentina Roviezzo, Antonietta Rossi, Elisabetta Caiazzo, Pierangelo Orlando, Maria A. Riemma, Valentina M. Iacono, Andrea Guarino, Armando Ialenti, Carla Cicala, Alessio Peritore, Raffaele Capasso, Vincenzo Di Marzo, Angelo A. Izzo

Publikováno v: Frontiers in Pharmacology, Vol 8 (2017)

One important risk factor for the development of asthma is allergen sensitization. Recent increasing evidence suggests a prominent role of mast cells in asthma pathophysiology. Since Palmitoylethanolamide (PEA), an endogenous lipid mediator chemicall

Externí odkaz: https://doaj.org/article/84d8cb0cc2214f2a86ffc0e1706eff38

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