Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carl-g. Regårdh"'
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 2:347-364
The pharmacokinetics of3H-metoprolol, a new selective β1-receptor antagonist, have been studied in healthy volunteers by following the plasma concentrations and the urinary excretion of the unchanged compound and its total radioactive metabolites af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9420bcb59be62adbcb663256ad01f40
https://doi.org/10.1007/bf01061407
https://doi.org/10.1007/bf01061407
Publikováno v:
Journal of Cardiovascular Pharmacology. 2:715-724
The pharmacokinetics of metoprolol and propranolol in 6 healthy volunteers were compared after an intravenous dose of 10 mg of each drug. The mean t1/2, beta was 3.6 hr for both drugs, but due to a larger volume of distribution, the total body cleara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87e8ac3477b21c06c061b1e65f954a7
https://doi.org/10.1097/00005344-198011000-00002
https://doi.org/10.1097/00005344-198011000-00002
Autor:
Carl G. Regårdh
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 10:337-349
The renal excretion of drugs is mainly controlled by three factors: glomerular filtration, tubular secretion and tubular reabsorption. Only relatively polar drugs are excreted in appreciable amounts by the kidneys. Factors affecting renal excretion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cb7302b87d0007a5a74d030b4d39a5
https://doi.org/10.1111/j.1365-2710.1985.tb00932.x
https://doi.org/10.1111/j.1365-2710.1985.tb00932.x
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 7(6)
The serum and urinary concentrations of 5-FU after continuous portal and jugular infusion have been followed by means of a highly sensitive microbiological assay method. Our data indicate that more than 90% of 5-FU was eliminated in the liver after c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db7740b19334ddbe8034a9b17a4e363
https://pubmed.ncbi.nlm.nih.gov/529028
https://pubmed.ncbi.nlm.nih.gov/529028