Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carl-Olof Sjöberg"'
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery
Background: Many substances used in inhalation research are water soluble and can be administered as nebulized solutions. Typical examples are therapeutic, small-molecular agents, or macromolecules. Another category is a number of water-soluble agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2199fd5f24594a766ff92be1dbd1ca
http://europepmc.org/articles/PMC7133437
http://europepmc.org/articles/PMC7133437
Autor:
You Xu, Laure Harinck, Abhijeet G. Lokras, Per Gerde, Ewa Selg, Carl-Olof Sjöberg, Henrik Franzyk, Aneesh Thakur, Camilla Foged
Publikováno v:
Xu, Y, Harinck, L, Lokras, A G, Gerde, P, Selg, E, Sjöberg, C-O, Franzyk, H, Thakur, A & Foged, C 2022, ' Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles ', International Journal of Pharmaceutics, vol. 621, 121758 . https://doi.org/10.1016/j.ijpharm.2022.121758
Thermostable dry powder inhaler (DPI) formulations with high aerosol performance are attractive inhalable solid dosage forms for local treatment of inflammatory lung diseases. We recently demonstrated that lipidoid-polymer hybrid nanoparticles (LPNs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c7136011c1b8d5b0ff6471a68f05d8
https://pubmed.ncbi.nlm.nih.gov/35483619
https://pubmed.ncbi.nlm.nih.gov/35483619
Autor:
Oleksiy Itsenko, Carl-Olof Sjöberg, Peter Sandblom, Christer Halldin, Johan Ulin, Lars-Anders Larsson, Kenneth Dahl, Magnus Schou, Obaidur Rahman
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 58:220-225
[(11)C]Carbon monoxide ((11)CO) is a versatile building block for the synthesis of Positron Emission Tomography (PET) radioligands. However, the difficulty of trapping (11)CO in a small solvent volume has limited its utility. We here report an evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d407bcc45c8dd98a5fe8adb29988b5
https://doi.org/10.1002/jlcr.3280
https://doi.org/10.1002/jlcr.3280
Publikováno v:
RSC Advances. 5:88886-88889
A novel gas–liquid segmented microfluidic platform has been developed. The Pd-mediated 11C-carbonylation reaction proceeds smoothly on this platform and good to excellent radiochemical conversions (RCC) were observed. Twelve compounds were successf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::532eb61689040c317e60b95da2aae22a
https://doi.org/10.1039/c5ra20646d
https://doi.org/10.1039/c5ra20646d
Autor:
Carl-Olof Sjöberg, Stefan Eirefelt, Maria Malmlöf, Lina Havsborn, Katarina Ekelund, Per Gerde, Pär Ewing
Publikováno v:
Assay and drug development technologies. 15(2)
The main purpose of this work was to develop an in vitro method for simulating the dissolution and absorption of inhaled dry powder drugs that also mimics systemic pharmacokinetic data. A second purpose was to evaluate this method. DissolvIt® was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28630ec1cdd07e278af61c85ba8e3106
https://pubmed.ncbi.nlm.nih.gov/28322599
https://pubmed.ncbi.nlm.nih.gov/28322599
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 26:181-189
The isolated perfused rat lung (IPL) is a suitable model for studying lung-specific pharmacokinetics (PK) of inhaled drugs. So far, little has been known, however, whether the PK measured in the ex vivo organ corresponds to the PK measured in similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653d651f04287400f7d9b501dba32ab5
https://doi.org/10.1089/jamp.2012.0971
https://doi.org/10.1089/jamp.2012.0971
Autor:
Kenneth, Dahl, Oleksiy, Itsenko, Obaidur, Rahman, Johan, Ulin, Carl-Olof, Sjöberg, Peter, Sandblom, Lars-Anders, Larsson, Magnus, Schou, Christer, Halldin
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 58(5)
[(11)C]Carbon monoxide ((11)CO) is a versatile building block for the synthesis of Positron Emission Tomography (PET) radioligands. However, the difficulty of trapping (11)CO in a small solvent volume has limited its utility. We here report an evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::156754a350bf54caa0480c7811ed75cc
https://pubmed.ncbi.nlm.nih.gov/25820685
https://pubmed.ncbi.nlm.nih.gov/25820685