Zobrazeno 1 - 10 of 161 pro vyhledávání: '"Carl-Henrik Nordström"'
1
Akademický článek
Effects of norepinephrine infusion on cerebral energy metabolism during experimental haemorrhagic shock
Autor: Rasmus Peter Jakobsen, Elisabeth Charlotte Hansen, Troels Halfeld Nielsen, Carl-Henrik Nordström, Palle Toft
Publikováno v: Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Background The use of norepinephrine in the case of life-threatening haemorrhagic shock is well established but widely discussed. The present study was designed to compare the effects of early norepinephrine treatment vs. no treatment on cer
Externí odkaz: https://doaj.org/article/49681f49aeb84dfbbb8a57af2d87de68
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2
Akademický článek
Bedside interpretation of cerebral energy metabolism utilizing microdialysis in neurosurgical and general intensive care
Autor: Carl-Henrik Nordström, Axel Forsse, Rasmus Peter Jakobsen, Simon Mölström, Troels Halfeldt Nielsen, Palle Toft, Urban Ungerstedt
Publikováno v: Frontiers in Neurology, Vol 13 (2022)
The microdialysis technique was initially developed for monitoring neurotransmitters in animals. In 1995 the technique was adopted to clinical use and bedside enzymatic analysis of glucose, pyruvate, lactate, glutamate and glycerol. Under clinical co
Externí odkaz: https://doaj.org/article/42d9509fa61448aaa25c24cb8c5a8c37
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3
Akademický článek
Moderately prolonged permissive hypotension results in reversible metabolic perturbation evaluated by intracerebral microdialysis - an experimental animal study
Autor: Rasmus Peter Jakobsen, Troels Halfeld Nielsen, Simon Mølstrøm, Carl-Henrik Nordström, Asger Granfeldt, Palle Toft
Publikováno v: Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Damage control resuscitation (DCR) and damage control surgery (DCS) is the main strategy in patients with uncontrollable hemorrhagic shock. One aspect of DCR is permissive hypotension. However, the duration of hypotension that can
Externí odkaz: https://doaj.org/article/6ffae2aa6d7240aea284a0aa4f3c309a
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4
Akademický článek
Ethyl Pyruvate Increases Post-Ischemic Levels of Mitochondrial Energy Metabolites: A 13C-Labeled Cerebral Microdialysis Study
Autor: Kevin H. Nygaard, Jesper F. Havelund, Troels H. Nielsen, Carl-Henrik Nordström, Nils. J. Færgeman, Frantz R. Poulsen, Jan Bert Gramsbergen, Axel Forsse
Publikováno v: Metabolites, Vol 10, Iss 7, p 287 (2020)
Mitochondrial dysfunction after transient cerebral ischemia can be monitored by cerebral microdialysis (CMD) using changes in the lactate and pyruvate concentrations and ratio. Other metabolites associated with mitochondrial (dys)function are, e.g.,
Externí odkaz: https://doaj.org/article/b95c25fe168148e28870d57fd8d847f1
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5
Akademický článek
Aspects on the Physiological and Biochemical Foundations of Neurocritical Care
Autor: Carl-Henrik Nordström, Lars-Owe Koskinen, Magnus Olivecrona
Publikováno v: Frontiers in Neurology, Vol 8 (2017)
Neurocritical care (NCC) is a branch of intensive care medicine characterized by specific physiological and biochemical monitoring techniques necessary for identifying cerebral adverse events and for evaluating specific therapies. Information is prim
Externí odkaz: https://doaj.org/article/4646097d62e84f97b1af10e78b89f7a8
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6
Akademický článek
In Vivo Microdialysis of Endogenous and 13C-labeled TCA Metabolites in Rat Brain: Reversible and Persistent Effects of Mitochondrial Inhibition and Transient Cerebral Ischemia
Autor: Jesper F. Havelund, Kevin H. Nygaard, Troels H. Nielsen, Carl-Henrik Nordström, Frantz R. Poulsen, Nils. J. Færgeman, Axel Forsse, Jan Bert Gramsbergen
Publikováno v: Metabolites, Vol 9, Iss 10, p 204 (2019)
Cerebral micro-dialysis allows continuous sampling of extracellular metabolites, including glucose, lactate and pyruvate. Transient ischemic events cause a rapid drop in glucose and a rise in lactate levels. Following such events, the lactate/pyruvat
Externí odkaz: https://doaj.org/article/56d8a78649124aa99f1b645961a14725
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8
Rapid selective brain cooling with PolarCap® - a commercial delusion?
Autor: Carl-Henrik, Nordström
Publikováno v: Journal of neurotrauma.
The recently published study on external head cooling after concussion in ice hockey players demonstrate a remarkable effect.The scientific basis of the results is, however, ambiguous and the cooling effect of the medical device used has not been pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0c72942158640588909301e6de8fba1
https://pubmed.ncbi.nlm.nih.gov/36448587
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9
Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients
Autor: Kirsten Møller, Michael Karlsson, Walter Fischer, Todd J. Kilbaugh, Matilda Hugerth, Ramona Åstrand, Eskil Elmér, Magnus Hansson, Marcus F. Keep, Jesper Kelsen, Zhihui Yang, Kevin K.W. Wang, Carl-Henrik Nordström, Marianne Juhler
Publikováno v: Kelsen, J, Karlsson, M, Hansson, M J, Yang, Z, Fischer, W, Hugerth, M, Nordström, C H, Åstrand, R, Keep, M F, Kilbaugh, T, Wang, K K W, Møller, K, Juhler, M & Elmér, E 2019, ' Copenhagen Head Injury Ciclosporin Study : A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients ', Journal of Neurotrauma, vol. 36, no. 23, pp. 3253-3263 . https://doi.org/10.1089/neu.2018.6369
Journal of Neurotrauma
Kelsen, J, Karlsson, M, Hansson, M J, Yang, Z, Fischer, W, Hugerth, M, Nordström, C-H, Åstrand, R, Keep, M F, Kilbaugh, T, Wang, K K W, Møller, K, Juhler, M & Elmér, E 2019, ' Copenhagen Head Injury Ciclosporin Study : A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients ', Journal of Neurotrauma, vol. 36, no. 23, pp. 3253-3263 . https://doi.org/10.1089/neu.2018.6369
Traumatic brain injury (TBI) contributes to almost one third of all trauma-related deaths, and those that survive often suffer from long-term physical and cognitive deficits. Ciclosporin (cyclosporine, cyclosporin A) has shown promising neuroprotecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd3907cba455eef78df56ab808153c0
https://doi.org/10.1089/neu.2018.6369
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10
Cerebral microdialysis after cardiac arrest – Misinterpretations based on a misconception
Autor: Simon Mølstrøm, Troels Halfeld Nielsen, Carl-Henrik Nordström, Rasmus Peter Jakobsen
Publikováno v: Nordström, C H, Jakobsen, R, Mølstrøm, S & Nielsen, T H 2021, ' Cerebral microdialysis after cardiac arrest – Misinterpretations based on a misconception ', Resuscitation, vol. 169, pp. 227-228 . https://doi.org/10.1016/j.resuscitation.2021.10.045
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f24f34a81a0a604ce667edd0da30db
https://doi.org/10.1016/j.resuscitation.2021.10.045
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