Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Carl Y. Saab"'
Autor:
Matheus Araujo, Samer Ghosn, Lu Wang, Nengah Hariadi, Samantha Wells, Carl Y. Saab, Reena Mehra
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Excessive daytime sleepiness (EDS) causes difficulty in concentrating and continuous fatigue during the day. In the clinical setting, the assessment and diagnosis of EDS rely mostly on subjective questionnaires and verbal reports, which comp
Externí odkaz:
https://doaj.org/article/7d9d7193aa364bbc9d4c0983f34ea336
Autor:
Helen Valsamis, Samah Abdul Baki, Jason Leung, Samer Ghosn, Brittany Lapin, Geetha Chari, Izad-Yar Rasheed, Jaehan Park, Vineet Punia, Ghinwa Masri, Dileep Nair, Ann Marie Kaniecki, Muhammad Edhi, Carl Y. Saab
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Coronavirus disease secondary to infection by SARS-CoV-2 (COVID19 or C19) causes respiratory illness, as well as severe neurological symptoms that have not been fully characterized. In a previous study, we developed a computational pipeline
Externí odkaz:
https://doaj.org/article/37b2a8b703184f579f8e8859213ffefb
Autor:
Matheus Araujo, Samer Ghosn, Lu Wang, Nengah Hariadi, Samantha Wells, Carl Y. Saab, Reena Mehra
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/cbfddd7e79cd423ea10b31cc302605ce
Autor:
Muhammad M. Edhi, Lonne Heijmans, Kevin N. Vanent, Kiernan Bloye, Amanda Baanante, Ki-Soo Jeong, Jason Leung, Changfang Zhu, Rosana Esteller, Carl Y. Saab
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Enhancing the efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and dependence on opioids. Present SCS therapies are characterized by the delivery of constant stimulation in the form of trains of ton
Externí odkaz:
https://doaj.org/article/13407e805180457ca6392ef3cb28ac16
Autor:
Joshua Levitt, Muhammad M. Edhi, Ryan V. Thorpe, Jason W. Leung, Mai Michishita, Suguru Koyama, Satoru Yoshikawa, Keith A. Scarfo, Alexios G. Carayannopoulos, Wendy Gu, Kyle H. Srivastava, Bryan A. Clark, Rosana Esteller, David A. Borton, Stephanie R. Jones, Carl Y. Saab
Publikováno v:
NeuroImage, Vol 223, Iss , Pp 117256- (2020)
Pain is a multidimensional experience mediated by distributed neural networks in the brain. To study this phenomenon, EEGs were collected from 20 subjects with chronic lumbar radiculopathy, 20 age and gender matched healthy subjects, and 17 subjects
Externí odkaz:
https://doaj.org/article/acd5de106f45437d977345838340ec06
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Paresthesia, a common feature of epidural spinal cord stimulation (SCS) for pain management, presents a challenge to the double-blind study design. Although sub-paresthesia SCS has been shown to be effective in alleviating pain, empirical cr
Externí odkaz:
https://doaj.org/article/a9111833c1f940ad87b61fc53d6ca57d
Autor:
Brian W. LeBlanc, Brent Cross, Kelsey A. Smith, Catherine Roach, Jimmy Xia, Yu-Chieh Chao, Joshua Levitt, Suguru Koyama, Christopher I. Moore, Carl Y. Saab
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract We tested the relation between pain behavior, theta (4–8 Hz) oscillations in somatosensory cortex and burst firing in thalamic neurons in vivo. Optically-induced thalamic bursts attenuated cortical theta and mechanical allodynia. It is pro
Externí odkaz:
https://doaj.org/article/1294ec178cf74cba946d2b0729643c9a
Publikováno v:
bioRxiv
Gamma band activity localized to the primary somatosensory cortex (S1) in humans and animals is implicated in the higher order neural processing of painful and tactile stimuli. However, it is unclear if gamma band activity differs between these disti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3dc230cc3c5b4fb8cc9d2a179afe3a
https://europepmc.org/articles/PMC10081264/
https://europepmc.org/articles/PMC10081264/
Spinal cord injury (SCI) is a significant neurologic illness that can result in devastating disability due to numerous complications of the disease. One of the most common and debilitating complications of SCI is chronic pain. Researchers have made c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff219f7801bea46fab6098d4992210ba
https://doi.org/10.1016/b978-0-12-818662-6.00005-4
https://doi.org/10.1016/b978-0-12-818662-6.00005-4
Autor:
Tor D. Wager, Mary Ann Pelleymounter, Jing Wang, Michael E. Burczynski, Joachim Scholz, Carl Y. Saab, Robert R. Edwards, Nima Aghaeepour, Brice Gaudilliere, Karen D. Davis, Georgene W. Hergenroeder, Christopher Crean, Yunyun Jiang, Märta Segerdahl, Michael J. Iadarola, Andrew H. Ahn, David Borsook, Ashley Brenton, Sean Mackey, Jiang-Ti Kong, Christine N. Sang, Christin Veasley, Martin S. Angst, Irene Tracey, Ajay D. Wasan, Smriti Iyengar
Publikováno v:
Nature Reviews. Neurology
Pain medication plays an important role in the treatment of acute and chronic pain conditions, but some drugs, opioids in particular, have been overprescribed or prescribed without adequate safeguards, leading to an alarming rise in medication-relate