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pro vyhledávání: '"Carl Walkley"'
The RNA editing enzyme Adenosine deaminase acting on RNA 1 (ADAR1) is an essential regulator of innate immune activation by both cellular and viral dsRNA. Adenosine-to-Inosine (A-to-I) editing by ADAR1 modifies the sequence and structure of endogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca847739fa191f667fe0cb6ed1db29f
https://doi.org/10.1101/2022.08.31.506069
https://doi.org/10.1101/2022.08.31.506069
Autor:
Carl Walkley
Publikováno v:
Blood. 139(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b9b4157cdd0c4bdb0c72eec77973f5
https://pubmed.ncbi.nlm.nih.gov/34665864
https://pubmed.ncbi.nlm.nih.gov/34665864
Autor:
Ting Zhang, Chaoran Yin, Aleksandr Fedorov, Liangjun Qiao, Hongliang Bao, Nazar Beknazarov, Shiyu Wang, Avishekh Gautam, Riley M. Williams, Jeremy Chase Crawford, Suraj Peri, Vasily Studitsky, Amer A. Beg, Paul G. Thomas, Carl Walkley, Yan Xu, Maria Poptsova, Alan Herbert, Siddharth Balachandran
Publikováno v:
Nature. 606(7914)
Only a small proportion of patients with cancer show lasting responses to immune checkpoint blockade (ICB)-based monotherapies. The RNA-editing enzyme ADAR1 is an emerging determinant of resistance to ICB therapy and prevents ICB responsiveness by re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5d36f61ff419a63a7cf3e7e2eeb6de
https://pubmed.ncbi.nlm.nih.gov/35915243
https://pubmed.ncbi.nlm.nih.gov/35915243
Autor:
Tram Anh Nguyen, Jia Wei Joel Heng, Pornchai Kaewsapsak, Eng Piew Louis Kok, Dominik Stanojević, Hao Liu, Angelysia Cardilla, Albert Praditya, Zirong Yi, Mingwan Lin, Jong Ghut Ashley Aw, Yin Ying Ho, Kai Lay Esther Peh, Yuanming Wang, Qixing Zhong, Jacki Heraud-Farlow, Shifeng Xue, Bruno Reversade, Carl Walkley, Ying Swan Ho, Mile Šikić, Yue Wan, Meng How Tan
Inosine is a prevalent RNA modification in animals and is formed when an adenosine is deaminated by the ADAR family of enzymes. Traditionally, inosines are identified indirectly as variants from Illumina RNA-sequencing data because they are interpret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29c545b8dbdee05a023973b5f3947c7
https://acuresearchbank.acu.edu.au/item/8y90y/direct-identification-of-a-to-i-editing-sites-with-nanopore-native-rna-sequencing
https://acuresearchbank.acu.edu.au/item/8y90y/direct-identification-of-a-to-i-editing-sites-with-nanopore-native-rna-sequencing