Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carl Tucker"'
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Decades of research have confirmed the beneficial and advantageous use of zebrafish (Danio rerio) as a model of human disease in biomedical studies. Not only are 71% of human genes shared with the zebrafish many of these genes are linked to human dis
Externí odkaz:
https://doaj.org/article/c2c9f77d2bcc443d95505ffe270421b9
Autor:
Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Carl Tucker, Sofia Ferreira-Gonzalez, Natalie Homer, Yu Wang, Philip J. Starkey Lewis, Enrique M Toledo, Esther Mellado-Gomez, Joanna Simpson, Oliver Flint, Himjyot Jaiswal, Nicola L. Beer, Allan E. Karlsen, Stuart J. Forbes, James W. Dear, Jeremy Hughes, David C. Hay
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102552- (2021)
Summary: Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In
Externí odkaz:
https://doaj.org/article/0fd0f2e5fb724e438758d7df1a29d1bc
Autor:
Suzanne Gillies, Rachel Verdon, Vicki Stone, David M. Brown, Theodore Henry, Lang Tran, Carl Tucker, Adriano G. Rossi, Charles R. Tyler, Helinor J. Johnston
Publikováno v:
Gillies, S, Verdon, R, Stone, V, Brown, D M, Henry, T, Tran, L, Tucker, C S, Rossi, A G, Tyler, C R & Johnston, H J 2022, ' Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials ', Nanotoxicology, vol. 16, no. 3, pp. 333-354 . https://doi.org/10.1080/17435390.2022.2088312
Hazard studies for nanomaterials (NMs) commonly assess whether they activate an inflammatory response. Such assessments often rely on rodents, but alternative models are needed to support the implementation of the 3Rs principles. Zebrafish (Danio rer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2495dedad06cb88f2f654be0bbb0a1f6
Autor:
Helinor J Johnston, Suzanne L J Gillies, Rachel Verdon, Vicki Stone, Theodore Henry, Lang Tran, Carl Tucker, Adriano G Rossi, Charles R Tyler
Publikováno v:
F1000Research. 12:51
Despite the increasing exploitation of nanomaterials (NMs) in an array of consumer products, there are uncertainties regarding their potential adverse impact on human health. Investigation of whether NMs activate a pro-inflammatory response is routin
Autor:
Monika Gostic, Angela Martinelli, Carl Tucker, Zhengyi Yang, Federico Gasparoli, Jade-Yi Ewart, Kishan Dholakia, Keith Sillar, Javier Tello, Silvia Paracchini
Dyslexia is a common neurodevelopmental disorder that affects reading abilities and is predicted to be caused by a significant genetic component. Very few genetic susceptibility factors have been identified so far and amongst those,KIAA0319is a key c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b99d6ac2c7d11c1e8921939564389b
https://doi.org/10.1101/267617
https://doi.org/10.1101/267617
Autor:
John J. Mullins, Calum A. MacRae, Matthew A. Bailey, Carl Tucker, Sebastien A. Rider, Jorge Del-Pozo, Kirsten N. Rose
Publikováno v:
The Journal of Physiology. 590:1803-1809
Zebrafish, a well-established vertebrate model, offer unique advantages for assessing renal function and physiology. Assays determining renal glomerular function based on cardiovascular erythrocyte flow and reduction of injected FITC-inulin were deve
Publikováno v:
HPCC/CSS/ICESS
Social networks have become an integral part of our society, and for good reason, which make it easier for people to keep in touch with their friends and family, while also generating new and interesting social data. However, the incredible volume of
Publikováno v:
Fisheries science. 68:1157-1160
Autor:
Martin A. Denvir, Christopher J. Kenyon, Kathryn S. Wilson, Carl Tucker, Gianfranco Matrone, John J. Mullins, Patrick W. F. Hadoke
Publikováno v:
Endocrine Abstracts.
Publikováno v:
2012 12th International Symposium on Pervasive Systems, Algorithms and Networks.
Stop signs are a part of everyday traffic for drivers around the world. However, due to their smaller size, lack of lighting and the fact that they can become visually obscured from the road, stop signs have a tendency to be much less effective than