Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Carl T. Brighton"'
Publikováno v:
Journal of Orthopaedic Research. 32:894-903
The objective of the described experiments was to determine the electrical parameters that lead to optimal expression of a number of bone-related genes in cultured human bone cells exposed to a capacitively coupled electric field. Human calvarial ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2831de5ac9bfd8581055c00eed07fe7
https://doi.org/10.1002/jor.22595
https://doi.org/10.1002/jor.22595
Publikováno v:
Open Journal of Biophysics. :158-164
We have previously shown that capacitively coupled electrical stimulation of either normal bovine articular chondrocytes or osteoarthritic human articular cartilage explants resulted in up-regulation of cartilage matrix gene expression and down-regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e794e2a8b4eafbb0adf5ae273cd62f1
https://doi.org/10.4236/ojbiphy.2013.32019
https://doi.org/10.4236/ojbiphy.2013.32019
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 90:833-848
Background: The destruction of cartilage in patients with osteoarthritis is a consequence of an imbalance between matrix synthesis and degradation. The purpose of the present study was to determine the effects of electrical stimulation on these proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa6481669f99237df158b0f3ae36a14
https://doi.org/10.2106/jbjs.f.01437
https://doi.org/10.2106/jbjs.f.01437
Publikováno v:
Biochemical and Biophysical Research Communications. 342:556-561
Electric stimulation has long been used as a tool to promote connective tissue healing, but the mechanism(s) by which this is accomplished are not yet known. We have previously determined, using mass cultures of fetal bovine articular chondrocytes, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6272618ac89a48da4ebd899ae835cc0b
https://doi.org/10.1016/j.bbrc.2006.01.171
https://doi.org/10.1016/j.bbrc.2006.01.171
Akademický článek
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Autor:
Dean G. Lorich, Mark E. Bolander, James Ryaby, Bruce J. Simon, Jason H. Nielson, Fred R.T. Nelson, John Seelig, Carl T. Brighton
Publikováno v:
Journal of the American Academy of Orthopaedic Surgeons. 11:344-354
During the past two decades, a number of physical modalities have been approved for the management of nonunions and delayed unions. Implantable direct current stimulation is effective in managing established nonunions of the extremities and as an adj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3775e6c02d9bd609bc77c5700ebe0c0c
https://doi.org/10.5435/00124635-200309000-00007
https://doi.org/10.5435/00124635-200309000-00007
Autor:
Carl T. Brighton
Publikováno v:
Clinical Orthopaedics and Related Research. 400:1-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f225763c976456d6ad47480da4d17836
https://doi.org/10.1097/00003086-200207000-00001
https://doi.org/10.1097/00003086-200207000-00001
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 83:1514-1523
Background: Electrical stimulation is used to treat nonunions and to augment spinal fusions. We studied the biochemical pathways that are activated in signal transduction when various types of electrical stimulation are applied to bone cells. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d5f70efd61c2fa27c98ee8f19f60a3
https://doi.org/10.2106/00004623-200110000-00009
https://doi.org/10.2106/00004623-200110000-00009
Publikováno v:
Biochemical and Biophysical Research Communications. 269:172-178
Multipotential mesenchymal stem cells capable of chondro-osseous induction contribute to the endochondral callus of healing fractured bone. Microvascular pericytes serving the role of multipotential mesenchymal stem cells are considered osteoprogenit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32fad5399b14944120321ce216aeaa8
https://doi.org/10.1006/bbrc.2000.2148
https://doi.org/10.1006/bbrc.2000.2148
Autor:
Craig L. Levitz, Hongming Zhuang, A. David Tahernia, Richard M. Seldes, Wei Wang, Carl T. Brighton, Huijun Fan
Publikováno v:
IUBMB Life. 43:339-346
Mechanical stimulation can prompt healing of bone fractures. However, it is largely unknown how osteogenesis is promoted by mechanical stimulation. In this study, we found that mechanical strain-induced proliferation of osteoblastic cells (MC3T3-E1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cef80d17468ac82c265c713142db1a
https://doi.org/10.1080/15216549700204121
https://doi.org/10.1080/15216549700204121