Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Carl Sheridan"'
Autor:
Chelsey Doyle, Breedge Callaghan, Anton W. Roodnat, Lee Armstrong, Karen Lester, David A. Simpson, Sarah D. Atkinson, Carl Sheridan, Declan J. McKenna, Colin E. Willoughby
Publikováno v:
Cells, Vol 13, Iss 12, p 1060 (2024)
Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with a complex, multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically modifiable risk factor for POAG. All current pharmacological agents targ
Externí odkaz:
https://doaj.org/article/1c09fcdb673a4b6e99c2ab2666f7101c
Autor:
Breedge Callaghan, Karen Lester, Brian Lane, Xiaochen Fan, Katarzyna Goljanek-Whysall, David A. Simpson, Carl Sheridan, Colin E. Willoughby
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Glaucoma is a complex neurodegenerative disease resulting in progressive optic neuropathy and is a leading cause of irreversible blindness worldwide. Primary open angle glaucoma (POAG) is the predominant form affecting 65.5 million people gl
Externí odkaz:
https://doaj.org/article/e362a150588a41c7a96fbb1f99eb0c20
Autor:
Kandasamy Kathirvel, Lester Karen, Ravinarayanan Haribalaganesh, Ramasamy Krishnadas, Veerappan Muthukkaruppan, Brian Lane, David A. Simpson, Kasia Goljanek-Whysall, Carl Sheridan, Devarajan Bharanidharan, Colin E. Willoughby, Srinivasan Senthilkumari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In the quest of identifying newer molecular targets for the management of glucocorticoid-induced ocular hypertension (GC-OHT) and glaucoma (GCG), several microarray studies have attempted to investigate the genome-wide transcriptome profilin
Externí odkaz:
https://doaj.org/article/45cf67c53c1f4538bc2c8bc176477bbb
Autor:
Anton W. Roodnat, Breedge Callaghan, Chelsey Doyle, Megan Henry, Katarzyna Goljanek-Whysall, David A. Simpson, Carl Sheridan, Sarah D. Atkinson, Colin E. Willoughby
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1693 (2022)
Pseudoexfoliation glaucoma (XFG) is an aggressive form of secondary open angle glaucoma, characterised by the production of exfoliation material and is estimated to affect 30 million people worldwide. Activation of the TGF-β pathway by TGF-β1 has b
Externí odkaz:
https://doaj.org/article/2f7290ed93f54f71b3e146662ec69552
Autor:
Kandasamy Kathirvel, Karen Lester, Ravinarayanan Haribalaganesh, Ramasamy Krishnadas, Veerappan Muthukkaruppan, Brian Lane, David A. Simpson, Kasia Goljanek-Whysall, Carl Sheridan, Devarajan Bharanidharan, Colin E. Willoughby, Srinivasan Senthilkumari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7707ca87df6d4148ad75b4e8d7333852
Publikováno v:
Journal of Ophthalmology, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/d69800ad5ce74f26827e00cad497a2be
Autor:
Claudio Campa, Ciro Costagliola, Carlo Incorvaia, Carl Sheridan, Francesco Semeraro, Katia De Nadai, Adolfo Sebastiani, Francesco Parmeggiani
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Choroidal neovascularization (CNV) is a common and severe complication in heterogeneous diseases affecting the posterior segment of the eye, the most frequent being represented by age-related macular degeneration. Although the term may suggest just a
Externí odkaz:
https://doaj.org/article/4b0e966a32cf4714a897ad14340ef831
Autor:
Breedge Callaghan, Karen Lester, Brian Lane, Xiaochen Fan, Katarzyna Goljanek-Whysall, David A. Simpson, Carl Sheridan, Colin E. Willoughby
Publikováno v:
Callaghan, B, Lester, K, Lane, B, Fan, X, Goljanek-Whysall, K, Simpson, D A, Sheridan, C & Willoughby, C E 2022, ' Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-β2 ', Scientific Reports, vol. 12, 9564 . https://doi.org/10.1038/s41598-022-13573-8
Glaucoma is a complex neurodegenerative disease resulting in progressive optic neuropathy and is a leading cause of irreversible blindness worldwide. Primary open angle glaucoma (POAG) is the predominant form affecting 65.5 million people globally. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c691b7a5a5a1f499b291fbdc0dc9921
https://doi.org/10.21203/rs.3.rs-955522/v1
https://doi.org/10.21203/rs.3.rs-955522/v1
Autor:
Xiaochen Fan, Carl Sheridan, Olivia A. Kingston, Rachel A. Oldershaw, Emine Kubra Bilir, Colin E. Willoughby, Victoria Kearns
Publikováno v:
Biomolecules, Vol 11, Iss 1371, p 1371 (2021)
BIOMOLECULES
Biomolecules
BIOMOLECULES
Biomolecules
Glaucoma is one of the leading causes of vision loss worldwide, characterised with irreversible optic nerve damage and progressive vision loss. Primary open-angle glaucoma (POAG) is a subset of glaucoma, characterised by normal anterior chamber angle
Publikováno v:
Bioengineering
Bioengineering, Vol 8, Iss 135, p 135 (2021)
Bioengineering, Vol 8, Iss 135, p 135 (2021)
The anterior segment of the eye is a complex set of structures that collectively act to maintain the integrity of the globe and direct light towards the posteriorly located retina. The eye is exposed to numerous physical and environmental insults suc