Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Carl S. Tucker"'
Autor:
Jonathan M. Taylor, Carl J. Nelson, Finnius A. Bruton, Aryan Kaveh, Charlotte Buckley, Carl S. Tucker, Adriano G. Rossi, John J. Mullins, Martin A. Denvir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Imaging heart development is challenging due to constant tissue movement and changing physical landmarks. Here the authors present an algorithm capable of maintaining phase-locked imaging throughout a 24 hour timespan, enabling long term timelapse im
Externí odkaz:
https://doaj.org/article/178169f074c049959cd3251b5dd86533
Autor:
Aryan Kaveh, Finnius A. Bruton, Charlotte Buckley, Magdalena E. M. Oremek, Carl S. Tucker, John J. Mullins, Jonathan M. Taylor, Adriano G. Rossi, Martin A. Denvir
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neutrophils and macrophages are crucial effectors and modulators of repair and regeneration following myocardial infarction, but they cannot be easily observed in vivo in mammalian models. Hence many studies have utilized larval zebrafish injury mode
Externí odkaz:
https://doaj.org/article/cc36592bdbb1414998961f121fe7fa7b
Autor:
Jonathan M. Taylor, Carl J. Nelson, Finnius A. Bruton, Aryan Kaveh, Charlotte Buckley, Carl S. Tucker, Adriano G. Rossi, John J. Mullins, Martin A. Denvir
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a8c67e27264340df8c306d453fbabc8b
Autor:
Carl S. Tucker, Carl J. Nelson, John J. Mullins, Aryan Kaveh, Finnius A. Bruton, Adriano G. Rossi, Charlotte Buckley, Martin A. Denvir, Jonathan M. Taylor
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Taylor, J M, Nelson, C J, Bruton, F A, Kaveh, A, Buckley, C, Tucker, C S, Rossi, A G, Mullins, J J & Denvir, M A 2019, ' Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart ', Nature Communications, vol. 10, 5173 . https://doi.org/10.1038/s41467-019-13112-6
Nature Communications
Taylor, J M, Nelson, C J, Bruton, F A, Kaveh, A, Buckley, C, Tucker, C S, Rossi, A G, Mullins, J J & Denvir, M A 2019, ' Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart ', Nature Communications, vol. 10, 5173 . https://doi.org/10.1038/s41467-019-13112-6
Nature Communications
Three-dimensional fluorescence time-lapse imaging of the beating heart is extremely challenging, due to the heart’s constant motion and a need to avoid pharmacological or phototoxic damage. Although real-time triggered imaging can computationally
Publikováno v:
Frontiers in Medicine
Tucker, C, Collins, R, Denvir, M A & McDougald, W A 2021, ' PET/CT TECHNOLOGY IN ADULT ZEBRAFISH: A PILOT STUDY TOWARD LIVE LONGITUDIANAL IMAGING ', Frontiers in Medicine . https://doi.org/10.3389/fmed.2021.725548
Frontiers in Medicine, Vol 8 (2021)
Tucker, C, Collins, R, Denvir, M A & McDougald, W A 2021, ' PET/CT TECHNOLOGY IN ADULT ZEBRAFISH: A PILOT STUDY TOWARD LIVE LONGITUDIANAL IMAGING ', Frontiers in Medicine . https://doi.org/10.3389/fmed.2021.725548
Frontiers in Medicine, Vol 8 (2021)
Decades of research have confirmed the beneficial and advantageous use of zebrafish (Danio rerio) as a model of human disease in biomedical studies. Not only are 71% of human genes shared with the zebrafish many of these genes are linked to human dis
Autor:
Finnius A. Bruton, Aryan Kaveh, Katherine M. Ross-Stewart, Gianfranco Matrone, Magdalena E.M. Oremek, Emmanouil G. Solomonidis, Carl S. Tucker, John J. Mullins, Christopher D. Lucas, Mairi Brittan, Jonathan M. Taylor, Adriano G. Rossi, Martin A. Denvir
Publikováno v:
Bruton, F, Kaveh, A, Ross Stewart, K, Matrone, G, Oremek, M, Solomonidis, E, Tucker, C, Mullins, J, Lucas, C D, Brittan, M, Taylor, J M, Rossi, A G & Denvir, M A 2022, ' Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration ', Developmental Cell, vol. 57, no. 12, pp. 1512-1528 . https://doi.org/10.1016/j.devcel.2022.05.014
Cardiac injury leads to the loss of cardiomyocytes, which are rapidly replaced by the proliferation of the surviving cells in zebrafish, but not in mammals. In both the regenerative zebrafish and non-regenerative mammals, cardiac injury induces a sus
Autor:
Himjyot Jaiswal, Philip J. Starkey Lewis, Carl S. Tucker, James W. Dear, Joanna Simpson, Jeremy Hughes, Oliver Flint, Sofia Ferreira-Gonzalez, Baltasar Lucendo-Villarin, Natalie Z.M. Homer, Esther Mellado-Gomez, Stuart J. Forbes, Enrique M. Toledo, Allan E. Karlsen, Nicola L. Beer, Jose Meseguer-Ripolles, David C. Hay, Yu Wang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102552-(2021)
iScience
Meseguer Ripolles, J, Lucendo Villarin, B, Tucker, C, Ferreira-Gonzalez, S, Homer, N Z M, Wang, Y, Starkey Lewis, P, Toledo Maldonado, E, Mellado-Gomez, E, Simpson, J, Flint, O, Jaiswal, H, Beer, N L, Karlsen, A E, Forbes, S J, Dear, J W, Hughes, J & Hay, D C 2021, ' Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure ', iScience . https://doi.org/10.1016/j.isci.2021.102552
iScience
Meseguer Ripolles, J, Lucendo Villarin, B, Tucker, C, Ferreira-Gonzalez, S, Homer, N Z M, Wang, Y, Starkey Lewis, P, Toledo Maldonado, E, Mellado-Gomez, E, Simpson, J, Flint, O, Jaiswal, H, Beer, N L, Karlsen, A E, Forbes, S J, Dear, J W, Hughes, J & Hay, D C 2021, ' Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure ', iScience . https://doi.org/10.1016/j.isci.2021.102552
Summary Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In t
Autor:
Adriano G. Rossi, Aryan Kaveh, Finnius A. Bruton, Carl S. Tucker, Martin A. Denvir, Magdalena E. M. Oremek, John J. Mullins, Jonathan M. Taylor
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
Kaveh, A, Bruton, F, Oremek, M, Tucker, C S, Taylor, J M, Mullins, J J, Rossi, A G & Denvir, M A 2021, ' Selective CDK9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish ', Development . https://doi.org/10.1242/dev.199636
article-version (VoR) Version of Record
Kaveh, A, Bruton, F, Oremek, M, Tucker, C S, Taylor, J M, Mullins, J J, Rossi, A G & Denvir, M A 2021, ' Selective CDK9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish ', Development . https://doi.org/10.1242/dev.199636
Sustained neutrophilic inflammation is detrimental for cardiac repair and associated with adverse outcomes following myocardial infarction (MI). An attractive therapeutic strategy to treat MI is to reduce or remove infiltrating neutrophils to promote
Autor:
Carl S. Tucker, Emmanouil G Solomonidis, Jonathan M. Taylor, Gianfranco Matrone, Martin A. Denvir, Magdalena E. M. Oremek, Katherine M. Ross-Stewart, Adriano G. Rossi, Aryan Kaveh, Finnius A. Bruton, Mairi Brittan, John J. Mullins
Publikováno v:
SSRN Electronic Journal.
Cardiac injury leads to the loss of cardiomyocytes which are rapidly replaced by proliferation of surviving cells in zebrafish, but not in mammals. In both the regenerative zebrafish and non-regenerative mammals, cardiac injury induces a sustained ma
Autor:
Amy M Dorward, Marcel Schubert, Gareth B. Miles, Malte C. Gather, Paul L. Appleton, Isla Rose Mary Barnard, Lewis Woolfson, Becky Casement, Gavin B. Robertson, Samantha J. Pitt, Andrew Morton, Carl S. Tucker
Publikováno v:
Nature Photonics
Funding: This research was financially supported by the European Research Council under the European Union’s Horizon 2020 Framework Programme (FP/2014-2020)/ERC grant agreement no. 640012 (ABLASE), by EPSRC (grant no. EP/P030017/1) and by the RS Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a3339696e09031646edd0dbd642251
https://hdl.handle.net/10023/21149
https://hdl.handle.net/10023/21149