Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Carl R. Rankin"'
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Akademický článek
Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation
Autor: Artin Soroosh, Kai Fang, Jill M. Hoffman, Ivy K. M. Law, Elizabeth Videlock, Zulfiqar A. Lokhandwala, Jonathan J. Zhao, Sepehr Hamidi, David M. Padua, Mark R. Frey, Charalabos Pothoulakis, Carl R. Rankin
Publikováno v: Cell Death and Disease, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently reported that microRNA-24-3p (miR-24-3p) is elevated in the colonic epithelium of ulce
Externí odkaz: https://doaj.org/article/5287751618ee4a859b6c22022f8d9350
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3
Akademický článek
Here to Heal: Mucosal CD74 Signaling in Colitis
Autor: Jill M. Hoffman, PhD, Carl R. Rankin, PhD, Charalabos Pothoulakis, MD
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 197-198 (2020)
Externí odkaz: https://doaj.org/article/9a7ada37c5374b60a882eb5dff5f0cb8
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5
The IBD-associated long noncoding RNA IFNG-AS1 regulates the balance between inflammatory and anti-inflammatory cytokine production after T-cell stimulation
Autor: Carl R. Rankin, Julie Elliott, Charalabos Pothoulakis, Jenny S. Sauk, David Padua, Omeed Alipour, Melissa Corson, Alakh Gulati, Elizabeth J. Videlock, Nimah Ather, Lorraine Rowe, Ling Shao, Ami Patel, Jihane N. Benhammou
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G34-G40
The inflammatory bowel diseases (IBD) are a complex set of chronic gastrointestinal inflammatory conditions arising from the interplay of genetic and environmental factors. This study focuses on noncoding RNA transcripts as potential mediators of IBD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::594a78231e9ebd92de0fa34ce462bf28
https://doi.org/10.1152/ajpgi.00232.2019
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6
Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation‐Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl‐Coenzyme A Desaturase As an Enhancer RNA
Autor: Joseph R. Pisegna, Arthur Ko, Minna U. Kaikkonen, Marcus Alvarez, Jihane N. Benhammou, Jussi Pihlajamäki, Kristina M. Garske, David Padua, Dorota Kaminska, Yash V. Bhagat, Päivi Pajukanta, Vesa Kärjä, Carl R. Rankin
Publikováno v: Hepatology Communications
Hepatology Communications, Vol 3, Iss 10, Pp 1356-1372 (2019)
The global obesity epidemic is driving the concomitant rise in nonalcoholic fatty liver disease (NAFLD). To identify new genes involved in central liver functions, we examined liver RNA‐sequence data from 259 patients who underwent morbidly obese b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704f57ee2a4eb4ea537fdb4e0f6027aa
https://doi.org/10.1002/hep4.1413
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9
The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p Are Downregulated in Irritable Bowel Syndrome and Are Associated With Barrier Function and MAPK Signaling
Autor: Ariela Khandadash, Lin Chang, Artin Soroosh, Charalabos Pothoulakis, Carl R. Rankin, Abhishek Verma, Elizabeth J. Videlock, Emeran A. Mayer, Swapna Mahurkar-Joshi, Dimitrios Iliopoulos
Publikováno v: Gastroenterology
Gastroenterology, vol 160, iss 7
Background & aimsAlterations in microRNA (miRNA) and in the intestinal barrier are putative risk factors for irritable bowel syndrome (IBS). We aimed to identify differentially expressed colonic mucosal miRNAs, their targets in IBS compared to health
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89a1479ad29a1ec5b574ec9e90cdd84
https://pubmed.ncbi.nlm.nih.gov/33617890
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