Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Carl R, Flannery"'
Autor:
Jacqueline M. Chevalier, Garett B. Pearson, Nicole Nixon, Carl R. Flannery, Luis Campoy, Lisa A. Fortier
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 3, Iss 4, Pp 100139- (2023)
Introduction: Post-traumatic osteoarthritis (PTOA) develops following traumatic articular insult. One model system used to study the progression and treatment of PTOA is the destabilization of the medial meniscus (DMM) as first described by Glasson e
Externí odkaz:
https://doaj.org/article/16bf0f70856b45e98d5e498be7f84627
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 579 (2019)
Background: Cartilage regeneration requires a balance of anabolic and catabolic processes. Aim: To examine the susceptibility of fibromodulin (FMOD) and lumican (LUM) to degradation by MMP-13, ADAMTS-4 and ADAMTS-5, the three major degradative protei
Externí odkaz:
https://doaj.org/article/2b8d971a85124d7089c14b2257c4fd93
Autor:
Carl R. Flannery, Kelly E. Buddin, Laila Begum, Michael A. Nasert, Brooke Catalfamo, Eric J. Semler, Lisa A. Fortier
Publikováno v:
CARTILAGE. :194760352311597
Objective This study was conducted to compare therapeutically relevant properties of platelet-rich plasma (PRP), a commonly used autologous intra-articular treatment for osteoarthritis (OA), with those of a novel placental tissue particulate, PTP-001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eba29afbec019f88770e35e82380b75c
https://doi.org/10.1177/19476035231159748
https://doi.org/10.1177/19476035231159748
Autor:
M. Jacobs, Kathryn L. Kelley, Richard F. Loeser, Carl R. Flannery, Eric J. Semler, A. Dasgupta, Long Marc, Alessandra Pavesio, Scott A. Seaman, K.E. Buddin, Michael A. Nasert
Publikováno v:
Osteoarthritis and Cartilage. 28:S487-S489
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0110934227939a2758415ce52f823c22
https://doi.org/10.1016/j.joca.2020.02.763
https://doi.org/10.1016/j.joca.2020.02.763
Autor:
Julie R Graham, Angela Chamberland, Qingcong Lin, X Jian Li, David Dai, Weilan Zeng, Mark S Ryan, Moisés A Rivera-Bermúdez, Carl R Flannery, Zhiyong Yang
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74094 (2013)
HTRA1 is a member of the High Temperature Requirement (HTRA1) family of serine proteases, which play a role in several biological and pathological processes. In part, HTRA1 regulation occurs by inhibiting the TGF-β signaling pathway, however the mec
Externí odkaz:
https://doaj.org/article/ab0375a6f1aa4c439dea0daafd9d47b6
Autor:
Thierry Conrozier, Carl R. Flannery, Daniela Crandall, Helen Smith, Ross Leighton, Jane Fitzpatrick
Publikováno v:
Open Access Rheumatology : Research and Reviews
Background Pain and limitations in joint mobility associated with knee osteoarthritis (OA) are clinically challenging to manage, and advanced progression of disease can often lead to total knee arthroplasty. Intra-articular injection of hyaluronic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8cd14b22db0ba3f1be58ff7d997266
https://doi.org/10.2147/oarrr.s162127
https://doi.org/10.2147/oarrr.s162127
Cartilage regeneration requires a balance of anabolic and catabolic processes. This study examined the susceptibility of fibromodulin (FMOD) and lumican (LUM) to degradation by MMP-13, ADAMTS-4 and ADAMTS-5, the three major degradative proteinases in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaae79a650b4c75b8690902a326769c
https://doi.org/10.20944/preprints201812.0274.v1
https://doi.org/10.20944/preprints201812.0274.v1
Autor:
Peter Youssef, Ruby P. Estrella, Christine Y. Chuang, Carl R. Flannery, Megan S. Lord, Niclas G. Karlsson, John M. Whitelock
Publikováno v:
Connective Tissue Research. 53:132-141
Lubricin, also referred to as superficial zone protein, has been reported to be a proteoglycan. However, the structure of its glycosaminoglycan chain has not been well characterized, and this study was undertaken to investigate the structure of the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bcbfc7eeaaf9ff84b455122f04f09a
https://doi.org/10.3109/03008207.2011.614364
https://doi.org/10.3109/03008207.2011.614364
Publikováno v:
CARTILAGE. 1:298-305
Objective: To determine if lubricin was present in the surface layer of repair cartilage formed after autologous chondrocyte implantation (ACI). Design: Forty-three biopsies of repair tissue were taken from patients who had been treated with ACI 8 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38ab35dfcaccc501eb90c56554e4a97
https://doi.org/10.1177/1947603510370156
https://doi.org/10.1177/1947603510370156
Autor:
Yihe Wang, Julio Tejada, Ning Li, Sunil Nagpal, Carl R. Flannery, M.A. Rivera-Bermudez, Zhiyong Yang, Elisabeth A. Morris, Ken C. N. Chang, S.S. Glasson, Edward R. Lavallie, Lisa A. Collins-Racie, Mei Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 107:3734-3739
Osteoarthritis (OA), the most common arthritic condition in humans, is characterized by the progressive degeneration of articular cartilage accompanied by chronic joint pain. Inflammatory mediators, such as cytokines and prostaglandin E 2 (PGE 2 ) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d3e21ddd8aa3bc13ec7579bcb50018
https://doi.org/10.1073/pnas.0911377107
https://doi.org/10.1073/pnas.0911377107